Lars J. Lindstad

ORCID: 0000-0003-2146-7817
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Microbial Metabolites in Food Biotechnology
  • Probiotics and Fermented Foods
  • Polysaccharides and Plant Cell Walls
  • Gut microbiota and health
  • Enzyme Production and Characterization
  • Biofuel production and bioconversion
  • Food composition and properties

Norwegian University of Life Sciences
2019-2023

Commensal butyrate-producing bacteria belonging to the Firmicutes phylum are abundant in human gut and crucial for maintaining health. Currently, insight is lacking into how they target otherwise indigestible dietary fibers trophic interactions establish with other glycan degraders competitive environment.

10.1128/mbio.03628-20 article EN cc-by mBio 2021-06-11

β-mannans and xylans are important components of the plant cell wall they acetylated to be protected from degradation by glycoside hydrolases. widely present in human animal diets as fiber leguminous plants thickeners stabilizers processed foods. There many fully characterized acetylxylan esterases (AcXEs); however, enzymes deacetylating mannans less understood. Here we two carbohydrate esterases, Ri CE2 CE17, Firmicute Roseburia intestinalis , which together deacetylate complex...

10.1073/pnas.1915376117 article EN cc-by Proceedings of the National Academy of Sciences 2020-03-13

Non-carbohydrate modifications such as acetylations are widespread in food stuffs well they play important roles diverse biological processes. These meet the gut environment and removed from their carbohydrate substrates by resident microbiota. Among most abundant O-acetylations, contributing to polysaccharides physico-chemical properties viscosity gelling ability, reducing accessibility for glycosyl hydrolases, thus hindering polysaccharide degradation. Of particular note, O-acetylations...

10.1042/ebc20220161 article EN cc-by-nc-nd Essays in Biochemistry 2023-03-13

ABSTRACT β-Mannans are hemicelluloses that abundant in modern diets as components seed endosperms and common additives processed food. Currently, the collective understanding of β-mannan saccharification human colon is limited to a few keystone species, which presumably liberate low-molecular-weight mannooligosaccharide fragments become directly available surrounding microbial community. Here we show dominant butyrate-producer gut, Faecalibacterium prausnitzii , able acquire degrade various...

10.1101/2020.12.23.424282 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-12-26

Abstract β-Mannans and xylans are important components of the plant cell wall they acetylated to be protected from degradation by glycoside hydrolases. widely present in human animal diets as fiber leguminous plants thickeners stabilizers processed foods. There many fully characterized acetylxylan esterases (AcXEs), however, enzymes deacetylating mannans less understood. Here we two carbohydrate esterases, Ri CE2 CEX, Firmicute Roseburia intestinalis, which together deacetylate complex...

10.1101/788067 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-10-01
Coming Soon ...