Aim . To study the presence and severity of insomnia in patients with comorbid coronary heart disease (CHD) depressive disorder (DD). Materials methods The included 132 CHD (class II–III exertional angina after myocardial infarction experienced more than 6 months ago): 58 DD 74 without depression. Beck Depression Inventory (BDI) was used to diagnose DD. diagnosis all cases confirmed by a therapist. Sleep disturbances were assessed using Sheehan Patient-Rated Anxiety Scale (ShAS). data...

To assess the influence of comorbid affective disorders (AD) on clinical and dynamic indicators alcohol dependence syndrome (ADS), level aggression in patients, to examine gender differences. Two groups were analyzed: Group F10 (n = 149) included patients with ADS without AD, group + F3 61) AD. Clinical-psychopathological, clinical-follow-up, psychometric, statistical methods used. Comorbidity AD reduces differences duration lucid periods, depressogenic effects alcohol, levels physical...

Background: Depression and cognitive impairment are recognized complications of COVID-19. This study aimed to assess performance in clinically diagnosed post-COVID depression (PCD, n = 25) patients using neuropsychological testing. Methods: The involved 71 with matched control groups: recovered COVID-19 individuals without (n 18) prior history 19). A group was identified based on psychiatric diagnosis, a comparison (noPCD, 46) included participants neurological complications, excluding...

The aim was to study the clinical-psychopathological, clinical-follow-up, clinical-dynamic features of mood disorders (MD) and alcohol use disorder (AUD) with their comorbidity combinations. Materials methods . included 88 people AUD MD: 33 women (37.5%) 55 (62.5%) men. first group 31 patients (35,0%) without comorbid affective symptoms, second 29 (33.0%) MD dependence, third 28 (32.0%) MD. There were no statistically significant differences between groups by age sex composition, level...

Background: numerous studies indicate a high level of comorbidity bipolar disorder with other psychiatric disorders. Alcohol dependence is one the most common comorbid pathologies, along anxiety disorders and personality Objective: determination frequency BAR alcohol in patients specialized hospital identiашcation clinical dynamic features this comorbidity. Patients methods: unit, 188 diagnosed according to ICD-10 (136 women 52 men) were examined. The age female was 41.6 ± 14.4 years, male —...

Background: Depression is one of the most severe sequelae COVID-19, with major depressive disorder often characterized by disruption in white matter (WM) connectivity stemming from changes brain myelination. This study aimed to quantitatively assess myelination clinically diagnosed post-COVID depression (PCD) using recently proposed MRI method, macromolecular proton fraction (MPF) mapping. Methods: The involved 63 recovered COVID-19 patients (52 mild, 11 moderate, and 2 severe) at 13.5 ±...

Depression is one of the most severe sequelae COVID-19, with major depressive disorder often characterized by disruption in white matter (WM) connectivity , stemming from changes brain myelination. This study aimed to quantitatively assess myelination clinically diagnosed post-COVID depression using recently proposed MRI method, macromolecular proton fraction (MPF) mapping. The involved 63 recovered COVID-19 patients (52 mild, 11 moderate, 2 severe) at 13.5±10.0 months post-recovery, matched...

Objective: to identify the structure and clinical features of affective disorders (AD) efficiency antidepressants in in-patients with chronic coronary artery disease (ChCAD), living Tomsk Region. Materials м ethods. At a heart center, 1,131 patients ChCAD were examined: 290 persons (25.6%) AD revealed, among them 72.1% men ( n = 209) 27.9% women 81). Mean age was (63.5 ± 9.4) years (57.9 7.2) р 0.004). structure, main syndromes, severity depression anxiety according data self-questionnaires...

The aim of the study was to reveal clinical and dynamic characteristics affective disorders (AD) in comorbidity with alcohol addiction (AA). Materials methods. 65 patients [22 women (34%) 43 men (66%)] were examined. main group included 34 aged 44.5 [36.0; 51.5] comorbid comparison 31 45 years [32; 52] without narcological pathology. Compared groups matched by sex, age nosological structure (p > 0.05). following methods used study: psychopathological, follow-up, psychometric, statistical,...

Objective: to study cognitive functions and level of proteins acute brain damage in a group patients receiving Cerebrolysin, comparison the pre- postoperative period coronary artery bypass graft surgery. Materials methods. The open-label randomized comparative controlled parallel included 60 men. average age therapy with Cerebrolysin was 61.5 (57÷66) years, – 61 (56÷65) years ( р > 0.05) group. Results. Groups differed statistically significantly according left ventricular ejection...

The aim was to study the impact of late diagnostics bipolar disorder (BD) on main clinical and dynamic indicators, suicidal behavior, subjective evaluation social adaptation level, employment status patients. Patients methods: 121 in-patients (38 males, 31.4% 83 females, 68.6%) with a veried diagnosis (according ICD-10 criteria) were examined. A comparative indicators that could reect causes consequences delayed performed. rst group ( n = 46) included patients BD during initial visit...

Objective : to study clinical-biological features of affective disorders including their comorbidity with coronary artery disease and personality efficacy psychopharmacotherapy in these patients. Material Methods . In the first group at a heart station 290 patients chronic (209 men 81 women) were fully examined. The second included 120 (40 80 psychiatric hospital disorder comorbid disorders. third 29 depressive control (n=21). Results Data on significant clinical-dynamic, biological...

Objective : to study the incidence rate of personality and anxiety disorders their interrelationship in seniors medical university. Materials methods . The screening for detection using Generalized Anxiety Disorder-7 (GAD-7) Standardized Assessment Personality – Abbreviated Scale (SAPAS) scales included 104 senior-year students In studied sample, males (n = 46; 44.2%) females 58; 55.8%) (p < 0.05) were equally represented, average age men was 23 (23; 25) years, women 23) years....

Failure to diagnose bipolar disorder (BD) in time leads an increase suicide risk, worse prognosis of the disease, and socioeconomic burden. Aim : assess incidence comorbidity other mental behavioral disorders, as well sequence formation this multimorbidity. Patients methods Affective States Department Mental Health Research Institute TNRMC, 121 patients with a diagnosis were selected for study group according ICD-10 diagnostic criteria. The predominance women was revealed (n = 83; 68.6%; p...

Introduction Mood disorders in the elderly are a relevant clinical problem associated with high prevalence and frequent co-morbidity chronic somatic diseases. Objective Study of traits depression elder persons disorders. Methods The investigation was entered by 582 (women = 391 (67,1%), men 191 (32,9%)), mean age women has constituted 67,5 ± 5,8 years, - 62,1 3,8 years. Criteria inclusion Age 55 years higher, 60 level according to Beck Inventory more than 22 scores. Results Affective were...

Depression and cognitive impairment are recognized complications of COVID-19. This study aimed to assess performance in clinically diagnosed post-COVID depression (PCD) patients using neuropsychological testing. The involved 71 patients, with matched control groups: recovered COVID-19 individuals without (n=18) prior history (n=19). A group (PCD, n=25) was identified based on psychiatric diagnosis, a comparison (noPCD, n=46) included participants neurological complications, excluding...

BACKGROUND: The development of new drugs to improve the effectiveness treatment and rehabilitation programs for patients suffering from addiction diseases, which are non-addictive have a stimulating effect on detoxification processes in body, can increase therapy reduce cost treatment. A deficiency GABAergic inhibition brain structures plays leading role occurrence paroxysmalness. innovative anticonvulsant Galodif® (1-[(3-chlorophenyl)(phenyl)methyl]urea), GABAA receptor modulator, has low...

Introduction. Currently, the study of comorbidity, which is characteristic clinical picture modern patients, relevant. This also applies to psychiatric disorders in cardiovascular diseases, are common, affect social functioning and determine biological characteristics patients prognosis. Bipolar disorder coronary heart disease one example such a comorbidity. Recent evidence suggests that up 40% with bipolar die from disease. Aim: To frequency their dynamic features chronic artery assessment...

The contribution of comorbid with coronary artery disease (CAD) mood disorders (MD) into total mortality is contradictory. Objective To study frequency and time until death due to general causes in groups patients MD, without them as well interrelationship these indicators MD therapy antidepressants. Methods Inpatients chronic CAD ( n = 333) under conservative were investigated (31% females 103), 69% males 230), mean age 61.8 ± 9.8 years). Team cardiologists psychiatrists followed up for 7...

Introduction . Currently, clinical trials (CT) remain the only technology, which provides proof of efficacy and safety new drugs their subsequent release to market. Medical researcher informed consent (IC) are main (and often only) source information for patient about upcoming trials, thus have a direct impact on perception patient’s decision participation. However, degree influence these factors participants still remains unclear. Materials methods. A multicenter cross-sectional study was...

Aim. To determine gender differences in self-reported social functioning of patients with comorbidity affective disorders (ADs) and chronic coronary artery disease. Materials methods . Self-reported 248 cardiological (194 men (78.2%) 54 women (21.8%)) disease (CAD) ADs was studied using the Social Adaptation Self-evaluation Scale (SASS). The mean age CAD (57.2 ± 6.5) years, (59.3 7.1), p = 0.04. Qualitative quantitative indicators were investigated Mann – Whitney, Wilcoxon T-test; χ2...

Study of influence depression on assessment cardiovascular risk in IHD patients with components metabolic syndrome (MS). Among 376 (59,1±10,3 years) 72,9% had AH, 40,2% DM type 2 or disturbance tolerance to glucose (DTG), 45,9% obesity, 42,2% dyslipidemia (DLP). Methods investigation were as follows: clinicalpsychopathological, experimental-psychological, HADS, MADRS. Depressive disorders have been diagnosed 109 (29%) cardiologic institution. 79,8% affective disorders, 20,2% mixed...