A5103262357- Parkinson's Disease Mechanisms and Treatments
- Biochemical Analysis and Sensing Techniques
- Sleep and Wakefulness Research
- Neurological disorders and treatments
- Restless Legs Syndrome Research
- Olfactory and Sensory Function Studies
- Plant Physiology and Cultivation Studies
- Allelopathy and phytotoxic interactions
- Berry genetics and cultivation research
- Ginkgo biloba and Cashew Applications
- Medical Research and Treatments
- Genetic Neurodegenerative Diseases
- Dysphagia Assessment and Management
- Prostate Cancer Diagnosis and Treatment
- Functional Brain Connectivity Studies
- Phytochemical and Pharmacological Studies
- Whipple's Disease and Interleukins
- Natural Antidiabetic Agents Studies
- Flowering Plant Growth and Cultivation
- Nanocomposite Films for Food Packaging
- Health Systems, Economic Evaluations, Quality of Life
- Sharing Economy and Platforms
- Nuclear Receptors and Signaling
- Chromatography in Natural Products
- Fungal Plant Pathogen Control
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Third Hospital of Hebei Medical University
2022
Hebei Medical University
2022
Nagoya University of Commerce and Business
2021
Beijing Hospital
2017-2019
Tangshan People's Hospital
2018
Shenyang Pharmaceutical University
2016
Nanjing Institute of Vegetable Science
2012
Evidence regarding brain structural atrophy associated with Freezing of Gait (FOG) in Parkinson's disease (PD) is inconsistent. We analyzed cortical thickness and subcortical nuclei volumes using FreeSurfer two large PD cohorts. In cohort 1 (N = 316), multivariate analyses identified reduced pallidum ventral diencephalon (VDC) as significantly FOG presence. Validation the Progression Markers Initiative (PPMI) (cohort 2, N 94) demonstrated that decreased VDC volume at four-year follow-up...
Background Olfactory testing is a useful tool in the differential diagnosis of Parkinson's Disease (PD). Although fast and easy to use, high intercultural variability odor detection limits world-wide use most common test sets. Objective The aim this study was one commonly used olfactory tests (Sniffin' Sticks 12-identification test) an adapted version for Chinese population healthy subjects PD patients. Methods For purpose, cohorts 39 41 German patients as well 70 100 have been examined both...
We investigated retinal structure changes in patients with Parkinson’s disease (PD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and controls, explored the value of this method differential diagnosis. Spectral domain optical coherence tomography (SD-OCT) was used to measure peripapillary nerve fiber layer (pRNFL) thickness, macular thickness volume. PSP showed higher temporal pRNFL than PD MSA patients. Peripapillary RNFL could be for discriminating from PD. thinning...
Objectives . The aim of this study was to compare the Sniffin’ Sticks 12‐identification test (SIT‐12), China‐modified version SIT‐12 (Ch‐SIT‐12) and brief smell identification for Chinese (B‐SITC) in population Parkinson’s disease (PD) multiple system atrophy (MSA). Methods 36 patients with PD 7 MSA were enrolled study. Three olfactory testing methods (SIT‐12, Ch‐SIT‐12, B‐SITC) used function all participants. Furthermore, demographic clinical data collected. Results There no significant...
Learning outcomes Students will be able to analyse competitive situations of the focal firm in platform market, factors that make become dominant sharing economy through technology and firm’s motives growth strategies mergers acquisitions overseas expansion, as well give recommendations on move forward achieve maintain its position market. Case overview/synopsis On 4 th April, 2018, Meituan-Dianping (Meituan), a Chinese group-buying website for consumer products retail services acquired...
Objective To explore the influencing factors of fear progression among postoperative elderly patients with prostatic cancer. Methods From December 2016 to 2017, we selected 404 cancer surgical treatment Urinary Surgery in Tangshan People's Hospital as subjects by purposive sampling. All were investigated Fear Progression Questionnaire-Short Form (FoPQ-SF) , Readiness for Discharge (RHD) Chinese Version M. D. Anderson Symptom Inventory and Family Adaptability Cohesion Scale Ⅱ (FACES Ⅱ)...
Objective To investigate the prevalence of depression in Parkinson′s disease (PD) patients, analyze clinical features PD and evaluate its impact on quality life. Methods One hundred ninety-five patients 63 normol controls were recruited this study. The detailed information was documented. Unified Disease Rating Scale Hoehn-Yahr stage used to severity motor function impairment patients. Hamilton Depression (HAMD) Anxiety employed assess anxiety 39-item Questionnaire applied life....
Objective To investigate the incidence and severity of clinical rapid eye movement sleep behavior disorder (RBD) in Parkinson′s disease (PD), association with motor subtypes. Methods We recruited 187 patients PD(Hoehn-Yahr stageⅠ-Ⅲ) from outpatient department Beijing Hospital. The general information was collected Unified Disease Rating Scale (UPDRS) scores were caculated. divided into two subgroups as tremor dominant (TD) non-tremor (NTD). One hundred matched healthy controls (HC)...
Introduction: Sleep disorders are common in Parkinson’s disease (PD) and significantly impact quality of life. Herein, we surveyed the incidence severity sleep Chinese PD patients observed their relationship with dopaminergic drugs. Methods: We collected demographic information 232 patients. The were scale (PDSS) version. Data on drug intake converted to levodopa equivalent doses (LED). Results: average total score PDSS was 119.3 ± 19.7. There a significant difference scores between groups...
When people surf online, they share audio-visual materials and may have similar emotional reactions. We carry out this study to explore the neural mechanism of inter-brain synchronization (IBS) . Compared interaction between two persons, multilateral is more practical in IBS research. propose an inspection method based on brain connectivity analysis manifold measurement. It expected that can deal with problem heterogeneous data brought by paradigm. Specifically, algorithm was constructed...
Objective To analyze the clinical characteristics and related factors associated with impulse compulsive behaviors (ICBs) in Parkinson′s disease (PD). Methods Two hundred thirty-one PD outpatients were recruited from Beijing Hospital Chinese Medicine of Pinggu District November 2012 to 2015. Questionnaire for Impulse Compulsive Disorders Disease (QUIP) was used assess all subjects if they have ICBs or not. The general materials, medication utilized recorded, scales evaluate patients....
Objective To survey the prevalence and distribution of sleep disorders in patients with Parkinson disease (PD) to analyze influencing factors. Methods The were surveyed Disease Sleep Scale (PDSS) among 206 PD patients. The association age, course disease, cognitive function, motor depression, equivalent dose levodopa (LED) was analyzed. Results The overall PDSS score (116.9±21.4). three most frequent items quality(181/206, 87.9%), difficulty maintaining sleep(160/206, 77.7%)and...
Objective To analyze the impact of depressive symptoms on quality life in patients with Parkinson's disease(PD)based middle- and long-term follow-up study, to explore predictors for reduced PD patients. Methods Clinical data 80 were searched from electronic database our research center.Patients who had complete general information following unified disease rating scale(UPDRS), Hoehn Yahr scale(HY), mini-mental state examination(MMSE), Hamilton depression scale(HAMD), scale...
Serum Lp(a) is routinely detected by mass concentration in clinical laboratory, but the results of which cannot be standardized. On other hand, particle detection has gained increasing popularity and facilitated standardization testing practice. This study aimed to compare between patients with stroke healthy controls.The participants admitted Third Hospital Hebei Medical University January 2021 October were assigned hemorrhagic stroke, cerebral infarction control group. using Shenzhen...