A5060829128- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Glycosylation and Glycoproteins Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Pancreatic and Hepatic Oncology Research
- RNA Interference and Gene Delivery
- Genetic factors in colorectal cancer
- Carbohydrate Chemistry and Synthesis
- Single-cell and spatial transcriptomics
Peter MacCallum Cancer Centre
2015-2022
The University of Melbourne
2017
BC Cancer Agency
2016
University of British Columbia
2010
An accurate blood‐based RAS mutation assay to determine eligibility of metastatic colorectal cancer ( mCRC ) patients for anti‐ EGFR therapy would benefit clinical practice by better informing decisions administer treatment independent tissue availability. The objective this study was the level concordance between plasma and status in with gauge whether testing is a viable alternative standard‐of‐care tumor testing. performed on samples from newly diagnosed patients, or recurrent using...
We report the synthesis and characterization of multivalent mannose conjugates based on high molecular weight hyperbranched polyglycerols (HPG). A range glycoconjugates were synthesized from HPGs (up to 493 kDa) varying units (22−303 per HPG). Hemagglutination assays using fresh human red blood cells concanavalin (Con A) showed that HPG−mannose exhibited a large enhancement in relative potency (as as 40000) along with significant increment activity sugar 255). The size HPG scaffold number...