Jason T. Alexander

ORCID: 0000-0003-2159-0604
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About
Contact & Profiles
Research Areas
  • Diabetes Treatment and Management
  • Diabetes Management and Research
  • Venous Thromboembolism Diagnosis and Management
  • Pharmacology and Obesity Treatment
  • Healthcare Policy and Management
  • Primary Care and Health Outcomes
  • Pharmaceutical Practices and Patient Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Erythrocyte Function and Pathophysiology
  • Potassium and Related Disorders
  • Blood groups and transfusion
  • Health Systems, Economic Evaluations, Quality of Life
  • Esophageal and GI Pathology
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Diagnosis and Treatment of Venous Diseases
  • Gastrointestinal motility and disorders
  • High Altitude and Hypoxia
  • Hemoglobin structure and function
  • Blood transfusion and management
  • Balance, Gait, and Falls Prevention
  • Ocular Oncology and Treatments
  • Opioid Use Disorder Treatment
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Entomological Studies and Ecology
  • Bone and Joint Diseases

University of Chicago
2016-2025

Aberdeen Royal Infirmary
2024

University of Illinois Chicago
2024

Shaker Heights Public Library
2020

Veterans Health Administration
2013

Emory University
2013

Background: Guidelines recommend sodium–glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP1) receptor agonists as second-line therapy for patients with type 2 diabetes. Expanding their use first-line has been proposed but the clinical benefits may not outweigh costs. Objective: To evaluate lifetime cost-effectiveness of a strategy SGLT2 or GLP1 agonists. Design: Individual-level Monte Carlo–based Markov model. Data Sources: Randomized trials, Centers Disease Control...

10.7326/m21-2941 article EN Annals of Internal Medicine 2022-10-01

This JAMA Clinical Guidelines Synopsis summarizes the American College of Chest Physicians’ 2022 guideline on perioperative management patients taking oral anticoagulation or antiplatelet therapy who are undergoing an elective surgery procedure.

10.1001/jama.2024.5880 article EN JAMA 2024-06-20

This JAMA Clinical Guidelines Synopsis summarizes the American College of Gastroenterology’s 2023 guideline update on diagnosis and management celiac disease.

10.1001/jama.2024.5883 article EN JAMA 2024-06-26

This JAMA Clinical Guidelines Synopsis summarizes the 2023 ACC/AHA/ACCP/HRS guideline for diagnosis and management of atrial fibrillation.

10.1001/jama.2024.19565 article EN JAMA 2024-11-14

Background Clinical outcomes in transfused patients may be affected by the duration of blood storage, possibly due to red cell ( RBC )‐mediated disruption nitric oxide NO ) signaling, a key regulator vascular tone and flow. Study Design Methods AS ‐1 units stored up 42 days were sampled at selected storage times. Samples added aortic rings ex vivo, system where ‐mediated vasodilation could experimentally controlled. Results showed storage‐dependent changes plasma hemoglobin (Hb),...

10.1111/trf.12111 article EN Transfusion 2013-03-11

This article summarizes a 2022 clinical practice guideline on falls prevention and management in older adults from the World Falls Guidelines Initiative.

10.1001/jama.2023.26942 article EN JAMA 2024-03-27

Douglas Grbic, PhD; Dorothy A. Andriole, MD; Lindsay Roskovensky, BA; Mark Speicher, PhD, MHA; Keith Horvath, Lisa Howley, PhD

10.1001/jamanetworkopen.2024.54054 article EN cc-by-nc-nd JAMA Network Open 2025-01-09

This JAMA Clinical Guidelines Synopsis summarizes the 2022-2023 recommendations on evaluation and management of chronic venous disease lower extremities from Society for Vascular Surgery, American Venous Forum, Vein Lymphatic Society.

10.1001/jama.2025.1704 article EN JAMA 2025-04-02

This guideline synopsis summarizes the Endocrine Society guidelines for hypercalcemia of malignancy in adults.

10.1001/jamaoncol.2022.7941 article EN JAMA Oncology 2023-01-13

This JAMA Clinical Guidelines Synopsis summarizes the Centers for Disease Control and Prevention’s 2022 clinical practice guideline prescribing opioids pain.

10.1001/jama.2023.6539 article EN JAMA 2023-04-24

The practice of outpatient medicine is demanding, encompasses a wide scope practice, and leaves little time for internists to stay up date with the current literature. This article reviews 5 studies published in 2022 2023 that have potential change medicine. Topics covered include chronic kidney disease, secondary cardiovascular stones, obesity, lipid management.

10.3949/ccjm.91a.23056 article EN Cleveland Clinic Journal of Medicine 2024-01-01

This JAMA Clinical Guidelines Synopsis summarizes the American Academy of Dermatology’s 2023 guidelines for topical-therapy management adults with atopic dermatitis.

10.1001/jama.2023.17719 article EN JAMA 2023-10-27

We appreciate Ashley Lim's close read of our review. Regarding the use SGLT-2 inhibitors in patients without albuminuria, as we point out, EMPA-KIDNEY trial[1][1] was first large randomized trial to enroll with chronic kidney disease albuminuria.

10.3949/ccjm.91c.03002 article EN Cleveland Clinic Journal of Medicine 2024-03-01

This JAMA Clinical Guidelines Synopsis summarizes the 2023 American College of Gastroenterology guidelines on management patients with acute lower gastrointestinal bleeding.

10.1001/jama.2023.25841 article EN JAMA 2024-04-24

Abstract Background/Aims In light of drug safety warnings for Janus kinase inhibitors (JAKi), we aimed to evaluate the occurrence adverse events and identify reasons discontinuation JAKi in clinical practice. Methods Medical records all patients prescribed NHS Grampian from January 2021 2023 rheumatic diseases were retrospectively reviewed. Patient demographics, co-morbidities, treatment (including cardiovascular events) recorded. Results 160 JAKi. 131 (81.8%) had rheumatoid arthritis, 16...

10.1093/rheumatology/keae163.086 article EN other-oa Lara D. Veeken 2024-04-01

A 76-year-old woman presented to the hospital with chronic melena. She was normotensive and tachycardic. Findings of a physical examination were notable for marked pallor conjunctival rim. found have hemoglobin 3.4 g/dL.

10.7326/aimcc.2023.0381 article EN cc-by-nc-nd Annals of Internal Medicine Clinical Cases 2023-07-01

Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications Network Open Cardiology Dermatology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning /...

10.1001/jama.2021.9855 article EN JAMA 2021-08-24
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