Shuto Hirota

ORCID: 0000-0003-2159-3995
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About
Contact & Profiles
Research Areas
  • Biochemical and Molecular Research
  • HIV/AIDS drug development and treatment
  • Advanced biosensing and bioanalysis techniques
  • Chronic Lymphocytic Leukemia Research
  • Pancreatic and Hepatic Oncology Research
  • Liver Disease Diagnosis and Treatment
  • DNA Repair Mechanisms
  • Biomedical Ethics and Regulation
  • DNA and Nucleic Acid Chemistry
  • Alcohol Consumption and Health Effects
  • Diet, Metabolism, and Disease
  • Neurogenetic and Muscular Disorders Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Radiation Therapy and Dosimetry
  • Pharmaceutical industry and healthcare
  • Boron Compounds in Chemistry

Tohoku University
2020-2023

Although proper physician-industry financial relationships are essential for improving patient care, they can also cause potential conflicts of interest. However, little is known about the pathologist-industry relationships. Using 2013-2021 Open Payments Database, this cross-sectional study investigated both research and non-research payments to all pathologists in USA. Payment data were analyzed descriptively. Of 21,664 pathologists, 49.5% have received totaling $356.7 million from...

10.1136/jcp-2023-208901 article EN Journal of Clinical Pathology 2023-04-21

Synthetic phosphate-derived functional groups are important for controlling the function of bioactive molecules in vivo. Herein we describe development a new type biocompatible phosphate analog, fluorophosphoramidate (FPA) group that has characteristic P-F and P-N bonds. We found FPA with primary amino was relatively unstable aqueous solution converted to monophosphate, while secondary stable. Furthermore, by improving molecular design FPA, developed reaction which is intracellular...

10.1002/cmdc.202200188 article EN ChemMedChem 2022-04-08
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