- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Spine and Intervertebral Disc Pathology
- Neuroscience and Neuropharmacology Research
- Anesthesia and Pain Management
- Musculoskeletal pain and rehabilitation
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Spinal Hematomas and Complications
- Neurofibromatosis and Schwannoma Cases
- Cystic Fibrosis Research Advances
- Vagus Nerve Stimulation Research
- Neonatal and fetal brain pathology
- Meningioma and schwannoma management
- Appendicitis Diagnosis and Management
- Breast Lesions and Carcinomas
- Cancer and Skin Lesions
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Pancreatitis Pathology and Treatment
- Breast Cancer Treatment Studies
- Intracranial Aneurysms: Treatment and Complications
- Cancer Genomics and Diagnostics
St. Bonifatius Hospital
2016-2021
Kiel University
2013-2014
Siloah St. Trudpert Klinikum
2013
Johannes Wesling Klinikum Minden
2012
Evangelisches Krankenhaus Bielefeld
2008-2011
Krankenhaus Mara
2011
Bethel University
2008-2010
Cairo University
2008-2009
Object The aim of this study was to evaluate the long-term efficacy temporal lobe epilepsy (TLE) surgery and potential risk factors for seizure recurrence after surgery. Methods This retrospective included 434 consecutive adult patients who underwent TLE at Bethel Epilepsy Centre between 1991 2002. Results Hippocampal sclerosis found in 62% patients, gliosis 17.3%, tumors 20%, focal cortical dysplasia (FCD) 6.9%. Based on a Kaplan-Meier analysis, probability Engel Class I outcome overall...
The goal of this study was to evaluate the long-term outcome patients who underwent extratemporal epilepsy surgery and assess preoperative prognostic factors associated with seizure outcome.This retrospective included 154 consecutive adult at Bethel Epilepsy Centre, Bielefeld, Germany between 1991 2001. Seizure categorized based on modified Engel classification. Survival statistics were calculated using Kaplan-Meier curves, life tables, Cox regression models risk outcomes.Sixty-one (39.6%)...
Our aim was to determine the surgical outcome in adult patients with intractable extratemporal epilepsy and follow it over time.We retrospectively studied operative 218 consecutive lesions who underwent resective treatment for partial Bethel Epilepsy Center, Bielefeld, Germany, between 1991 2005. Patients were divided into three groups according 5-year period which procedure took place.Group I (1991-1995) consisted of 64 patients. The postoperative Engel Class 50% at 6 months, 44.4% 2 years,...
The aim of this study was to evaluate the short- and long-term seizure outcome find predictors after epilepsy surgery in lesional posterior cortical epilepsies (PCEs).The operative 80 consecutive adult patients with PCEs who underwent resective for intractable partial between 1991 2006 retrospectively studied.The probability remaining Engel Class I 66.3% (95% CI 60 72) at 6 months, 52.5% 47 57) 2 years, 52.9% (CI 45 59) 5 years 47.1% 42 52) 10 years. Factors predicting poor were presence a...
Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of 25-year-old male who presented generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters an intra- extra-axial lesion. Intraoperatively, lesion was cortical solid mass that had connections dura or ventricle. The histological diagnosis ependymoma WHO grade III distinctive desmoplasia. A literature...
Bithalamic infarction resulting from occlusion of the artery Percheron after cervical spine surgery is a rare pathological entity. Diagnosis and early detection are challenging. Prompt management may help to improve outcome. We present case 39-year-old male patient, smoker, diagnosed with multiple disc herniations, who underwent Anterior Cervical Discectomy Fusion (ACDF) for C3-C4, C4-C5, C5-C6. During 2-hour 50-minute surgery, patient was lying supine his neck hyperextended. The...
Primary osteosarcoma of the breast is an extremely rare lesion. The pathogenesis primary osteosarcomas controversial. We present case a 63-year-old white German woman who presented with mass in her right after routine screening. core needle biopsy showed ductal hyperplasia metaplastic ossification tissue. Complete excision lesion standard safety margins was performed. final diagnosis ossification. Three years later, our patient again painless lump about 15 × 8 7 cm, extending to lower part...
Posterior epidural migration of the lumbar disc fragment is a very rare pathological entity. The pathomechanisms remain unclear. authors present case 78-year-old Germans male with refractory low back pain. Contrast-MRI showed an mass at level L1–2 rim contrast enhancement. preoperative diagnosis based on clinical and history patient was most probably sequestrated migrated posteriorly; differential included all other causes posteriorly located mass. A left interlaminar approach performed....
Study Design: This is a retrospective, self-controlled cohort study, at single center. Objective: The aim of this study was to evaluate the long-term outcome sexual function after surgical treatment single-level lumbar disk herniation (LDH). Summary Background Data: impact on activity still unknown and not well researched. Materials Methods: In total, 114 patients who underwent surgery for LDH between 2009 2015 were included in (mean age, 46.9 y). Two separate questionnaires evaluating...
Intradural lumbar disc herniation (ILDH) is a very rare pathological entity. The pathomechanisms and the natural course remain unclear. authors present case of 58-year-old Germans male with repetitive microdiscectomies (MD) intraoperative missed diagnosis ILDH. patient underwent standard MD due to (LDH) at level L4/5. Incidental durotomy (ID) was sealed ventromedial patch. Postoperative uneventful. 14 months later presented L4 radiculopathy, having his second L3/4. At this point radiological...
Traumatic spondylolisthesis is the second most common C2 fractures, no Class I or II evidence exists regarding management of traumatic axis. A 74-year-old German male presented to our emergency room with complaints severe neck pain and difficulty in movements following a domestic accident 3 days ago. CT-cervical spine showed pedicle fracture right side without displacement angulation lamina contralateral side. We considered as potentially stable. Conservative treatment was recommended. The...
• We present a rare case of spinal GBM with leptomeningeal gliomatosis at the time diagnosis involving Brainstem presenting clinically typical subarachnoid hemorrhage in 39-year-old female. At admission, cerebral angiography, CT scan and MRI brain showed no abnormality except for not requiring therapy Isolate small developmental venous anomaly (DVA li.-frontal). Due to worsen headache, new 3-Tesla total neural axis has been performed, which demonstrated an unclear lesion intraspinal...
The maternal death rate remains unacceptably high worldwide, predominantly in areas of poor access to quality health services. According the WHO, 2017, 810 women died from preventable causes related pregnancy and childbirth. Causes are plenty, including previous morbidity unexpected causes. Among latter infectious disease-related deaths. Herein, we describe a case 29-year-old woman at 37 weeks' gestation who presented with right upper quadrant pain, which was initially considered be...
Fracture–dislocations of the cervical spine are potentially serious injuries. The goal management is adequate reduction and stabilization, usually, surgery required. Combined anterior–posterior stabilization recommended if either approach suboptimal. Spinal navigation has become safer, more accurate, popular among surgeons. Most published studies used spinal in fracture cases prone position, with head fixed to MAYFIELD® frame. sitting position less Navigation a challenge regarding operating...