A5100751649- Asthma and respiratory diseases
- IL-33, ST2, and ILC Pathways
- Eosinophilic Esophagitis
- Pediatric health and respiratory diseases
- RNA modifications and cancer
- Immune Response and Inflammation
- Inflammasome and immune disorders
- Galectins and Cancer Biology
- Vestibular and auditory disorders
- Circular RNAs in diseases
- Cytokine Signaling Pathways and Interactions
- Immune Cell Function and Interaction
- Hearing, Cochlea, Tinnitus, Genetics
- Air Quality and Health Impacts
- Allergic Rhinitis and Sensitization
- Ferroptosis and cancer prognosis
Nanchang University
2011-2025
Second Affiliated Hospital of Nanchang University
2011-2025
The CCR3 gene plays a critical role in allergic airway inflammation, such as rhinitis (AR), and there is an inflammatory signal link between the nasal cavity bone marrow. However, effects of marrow cells on AR are not clear. present study investigated roles underlying mechanisms mice. Conditional knockout (CKO) mice was generated using Cre-LoxP recombination system, offspring genotypes were identified polymerase chain reaction (PCR). An ovalbumin-induced model established CKO wild-type to...
The present study aimed to explore the microRNA-let-7e (miR-let-7e) expression in allergic rhinitis (AR), and investigate underlying molecular mechanisms. miR-let-7e nasal mucosa of mice patients with AR were detected. levels three inflammatory factors, including histamine, immunoglobulin E tumor necrosis factor-α (TNF-α), blood interleukin (IL)-13-stimulated epithelial cells (NECs) also measured. Furthermore, target gene was predicted validated using a luciferase reporter assay. Janus...
Background: In recent years, the incidence of sudden deafness has gradually increased, with a very limited understanding its etiology and pathogenesis. Glucocorticoids are first choice treatment, but some hormone-resistant patients not sensitive to glucocorticoid therapy. The pathogenesis is yet known. this study, we aim construct HEI-OC1 cell line stably overexpressing Glucocorticoid Receptor Beta (GRβ), identify exact role in cases glucocorticoidresistant deafness. Methods: We used...
Innate lymphoid cells（ILCs） have been found to be involved in innate immune responses recent years, and one of the subtypes group 2 cells is essential for development allergic airway inflammation. They are regulated by a variety protein molecules express corresponding cytokines play different roles. This article will briefly describe immunological properties current ILC2 its role rhinitis.