Agnieszka Surwiłło
A5003724272- Nutrition, Genetics, and Disease
- Nutritional Studies and Diet
- Consumer Attitudes and Food Labeling
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- BRCA gene mutations in cancer
- Biochemical Analysis and Sensing Techniques
- Vitamin D Research Studies
- Genetic Associations and Epidemiology
- Folate and B Vitamins Research
- Fatty Acid Research and Health
- Nutrition and Health Studies
- Physical Activity and Health
- Temporomandibular Joint Disorders
- Lipid metabolism and biosynthesis
- Agriculture Sustainability and Environmental Impact
- Textile materials and evaluations
- Cholesterol and Lipid Metabolism
- Mobile Health and mHealth Applications
- Cancer Risks and Factors
- Adrenal Hormones and Disorders
- Nutrition and Health in Aging
- Behavioral Health and Interventions
Instytut Zywnosci Zywienia
2014-2019
Cambridge University Press
2017
New York University Press
2017
Food & Nutrition
2017
Warsaw University of Life Sciences
2013
Background: Optimal nutritional choices are linked with better health, but many current interventions to improve diet have limited effect. We tested the hypothesis that providing personalized nutrition (PN) advice based on information individual and lifestyle, phenotype and/or genotype would promote larger, more appropriate, sustained changes in dietary behaviour. Methods: Adults from seven European countries were recruited an internet-delivered intervention (Food4Me) randomized to: (i)...
Objective To examine whether the effect of FTO loci on obesity‐related traits could be modified by physical activity (PA) levels in European adults. Methods Of 1,607 Food4Me participants randomized, 1,280 were genotyped for (rs9939609) and had available PA data. was measured objectively using accelerometers (TracmorD, Philips), whereas anthropometric measures [BMI waist circumference (WC)] self‐reported via Internet. Results genotype associated with a higher body weight [ β : 1.09 kg per...
Background: There is evidence that physical activity (PA) can attenuate the influence of fat mass- and obesity-associated (FTO) genotype on risk to develop obesity. However, whether providing personalized information FTO leads changes in PA unknown.
Abstract An efficient and robust method to measure vitamin D (25-hydroxy 3 (25(OH)D ) 25-hydroxy 2 in dried blood spots (DBS) has been developed applied the pan-European multi-centre, internet-based, personalised nutrition intervention study Food4Me. The includes calibration with containing endogenous 25(OH)D , spotted as DBS corrected for haematocrit content. methodology was validated following international standards. performance characteristics did not reach those of current gold standard...
Background: The high prevalence of physical inactivity worldwide calls for innovative and more effective ways to promote activity (PA). There are limited objective data on the effectiveness Web-based personalized feedback increasing PA in adults. Objective: It is hypothesized that providing advice based measured objectively alongside diet, phenotype, or genotype information would lead larger sustained changes PA, compared with nonpersonalized advice. Methods: A total 1607 adults seven...
Background: Despite numerous healthy eating campaigns, the prevalence of diets high in saturated fatty acids, sugar, and salt low fiber, fruit, vegetables remains high. With more people than ever accessing Internet, Web-based dietary assessment instruments have potential to promote healthier behaviors via personalized advice. Objective: The objectives this study were develop a feedback system for delivery consistent advice multicenter examine impact automating system. Methods: development...
The use of biomarkers in the objective assessment dietary intake is a high priority nutrition research. aim this study was to examine pentadecanoic acid (C15:0) and heptadecanoic (C17:0) as dairy foods intake.The data used present were obtained part Food4me Study. Estimates C15:0 C17:0 from dried blood spots intakes Food Frequency Questionnaire participants (n = 1180) across seven countries. Regression analyses explore associations with levels receiver operating characteristic evaluate fatty...
Abstract Traditionally, personalised nutrition was delivered at an individual level. However, the concept of delivering tailored dietary advice a group level through identification metabotypes or groups metabolically similar individuals has emerged. Although this approach to looks promising, further work is needed examine across wider population group. Therefore, objectives study are to: (1) identify in European and (2) develop targeted solutions for these metabotypes. Using data from...
Abstract The interplay between the fat mass- and obesity-associated ( FTO ) gene variants diet has been implicated in development of obesity. aim present analysis was to investigate associations genotype, dietary intakes anthropometrics among European adults. Participants Food4Me randomised controlled trial were genotyped for genotype (rs9939609) their intakes, quality scores (Healthy Eating Index PREDIMED-based Mediterranean score) estimated from FFQ. Relationships (weight, waist...
Abstract Individual response to dietary interventions can be highly variable. The phenotypic characteristics of those who will respond positively personalised advice are largely unknown. objective this study was compare the profiles differential responders intervention, with a focus on total circulating cholesterol. Subjects from Food4Me multi-centre were classified as or non-responders basis change in cholesterol level baseline month 6, lower and upper quartiles defined responder...
Scope Previous work highlighted the potential of odd‐chain length saturated fatty acids as markers dairy intake. The aim this study was to assess reproducibility these biomarkers and their sensitivity changes in Methods results Fatty acid profiles dietary intakes from food frequency questionnaires (FFQs) were measured three times over six months Food4Me Study. Reproducibility explored through intra‐class correlation coefficients (ICCs) within‐subject variation (WCV). Sensitivity diet...
It is hypothesised that individuals with knowledge of their genetic risk are more likely to make health-promoting dietary and lifestyle changes. The present study aims test this hypothesis using data from the Food4Me study. This was a 6-month Internet-based randomised controlled trial conducted across seven centres in Europe where received either general healthy eating advice or varying levels personalised nutrition advice. Participants who genotype-based were informed whether they had...
A high intake of n-3 PUFA provides health benefits via changes in the n-6/n-3 ratio blood. In addition to such dietary PUFAs, variants fatty acid desaturase 1 (FADS1) gene are also associated with altered profiles.We used mathematical modeling predict levels whole blood, based on multiple hypothesis testing and bootstrapped LASSO selected food items, anthropometric lifestyle factors, rs174546 genotypes FADS1 from 1607 participants (Food4Me Study). The models were developed using data first...
To characterise clusters of individuals based on adherence to dietary recommendations and determine whether changes in Healthy Eating Index (HEI) scores response a personalised nutrition (PN) intervention varied between clusters.Food4Me study participants were clustered according their baseline intakes met European recommendations. Changes HEI month 6 compared stratified by received generalised or PN advice.Pan-European, Internet-based, 6-month randomised controlled trial.Adults aged 18-79...
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Abstract Objective To characterise participants who dropped out of the Food4Me Proof-of-Principle study. Design The study was an Internet-based, 6-month, four-arm, randomised controlled trial. control group received generalised dietary and lifestyle recommendations, whereas to three different levels personalised nutrition (PN) advice based on dietary, phenotypic and/or genotypic data, respectively (with either more or less frequent feedback). Setting Seven recruitment sites: UK, Ireland,...