A5022194723- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS Research and Interventions
- SARS-CoV-2 detection and testing
- Complement system in diseases
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- COVID-19 Clinical Research Studies
- HIV, Drug Use, Sexual Risk
- Horticultural and Viticultural Research
- COVID-19 Impact on Reproduction
- Sex work and related issues
- Biosensors and Analytical Detection
- Fermentation and Sensory Analysis
- Monoclonal and Polyclonal Antibodies Research
- Immune Cell Function and Interaction
Centro Universitário Fundação Santo André
2024
Secretaria da Saúde
2022-2023
Universidade Estadual Paulista (Unesp)
2021
One year into the coronavirus disease 2019 (COVID-19) pandemic, diagnostic strategies, although central for contact tracing and other preventive measures, are still limited. To meet global demand, lower cost faster antigen tests severe acute respiratory syndrome 2 (SARS-CoV-2) detection a convenient alternative to gold standard reverse transcription-polymerase chain reaction (RT-PCR) assay. We tested laboratory-based RT-PCR RNA two rapid (RAD) tests, based on immunochromatography test...
Humoral response to SARS-CoV-2 has been studied, predominantly the classical IgG and its subclasses. Although IgE antibodies are typically specific allergens or parasites, a few reports describe their production in other viruses. Here, we investigated receptor binding domain (RBD) of Brazilian cohort following natural infection vaccination. Samples from 59 volunteers were assessed after (COVID-19), primary immunization with vectored (ChAdOx1) inactivated (CoronaVac) vaccines, booster mRNA...
Practical laboratory proxies that correlate to vaccine efficacy may facilitate trials, identify nonresponders, and inform about boosting strategies. Among clinical markers, assays evaluate antibodies inhibit receptor-binding domain (RBD) ligation angiotensin-converting enzyme-2 receptor (receptor-binding inhibition [RBI]) provide a surrogate for viral neutralization assays. We evaluated RBI before after median of 34 days (interquartile range [IQR]: 33-40) the second dose severe acute...
The world has been dealing with Aids for forty years, covid-19 accentuated societal inequalities and promoted a rupture in care prevention, including people living HIV. We compiled official HIV indicators, analyzed the impact of Brazil, at São Paulo State (SP), compared it to municipality Santo André (in state Paulo), which adopted linkage/retention strategies mitigate covid-19. From 2019 2020, suppression/adhesion rates remained stable. number new treatments decreased both Brazil (-19.75%)...
<title>Abstract</title> The humoral response of SARS-CoV-2 has been studied, primarily focusing on the classical IgG and subclasses. Although IgE antibodies are typically specific to allergens or parasites, a few reports describe its production in other viruses. Here, we investigated IgE-specific Receptor Binding Domain (RBD) Brazilian cohort following natural infection vaccination. Samples from 59 volunteers were assessed after (COVID-19), primary immunization with vectored (ChAdOx1)...
Two-Drug Regimens (2DR) have proven effective in clinical trials but real-world data, especially resource-limited settings, is limited.To evaluate viral suppression of lamivudine-based 2DR, with dolutegravir or ritonavir-boosted protease inhibitor (lopinavir/r, atazanavir/r darunavir/r), among all cases regardless selection criteria.A retrospective study, conducted an HIV clinic the metropolitan area São Paulo, Brazil. Per-protocol failure was defined as viremia above 200 copies/mL at...
Background: Antiretroviral therapy (ART) is free in Brazil and indicated for all people living with HIV since December 2013 regardless of CD4 T cell count. The benefits rapid ART include less risk AIDS non-AIDS conditions to the individual as well lower transmissibility (Undetectable = Untransmittable). However, introduction may take months after diagnosis an immediate treatment it not a priority many places. Method: We evaluated time loss follow-up (LTFU) 589 patients diagnosed up 6 months,...
QUANTIFICAÇÃO DO METABOLISMO RESPIROFERMENTATIVO DE LEVEDURAS CERVEJA, VINHO E PÃO POR MÉTODO ESTEQUIOMÉTRICO RICARDO FIGUEIRA1, LUCAS FELIPE DOS OUROS1, ISABELA PENTERICHE OLIVEIRA1, THALIA LEE LOPES ANDRADE1, WALDEMAR GASTONI VENTURINI FILHO1 1Departamento de Produção Vegetal/Área Horticultura, Faculdade Ciências Agronômicas, UNESP. Av. Universitária, 3780 - Altos do Paraíso, CEP 18610-034, Botucatu, SP, Brasil. ricardo.figueira@unesp.br; lucasouros@hotmail.com; isapenteriche@hotmail.com;...
We documented the outcome of an over 10-year (2011-2021) effort to diagnose acute and early HIV infections (AEHI) in Infectious Diseases Outpatient Clinic with limited resources. Of a total 132, 119 HIV-RNA tests were performed from 2017 2020, 12 cases identified, using simple algorithm: risk exposure 6 weeks or less before visit and/or symptoms compatible retroviral syndrome 7-30 days after undetermined 3rd generation rapid diagnostic test serology. AEHI diagnoses varied 2.4% among...
The COVID-19 pandemic in Brazil has been marked by high infection and death rates. immune response generated current vaccination might be influenced previous natural infection, baseline estimates may help the evaluation of vaccine-induced serological response. We evaluated SARS-CoV-2 testing (RT-PCR), performed rapid diagnostic tests (RDT) throughput electrochemiluminescence immunoassay (ECLIA) before among people living with HIV (PLWH), users antiretroviral prophylaxis (PrEP/PEP),...