A5050047175- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Transplantation: Methods and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Organ Transplantation Techniques and Outcomes
- Cardiac Imaging and Diagnostics
- Renal Transplantation Outcomes and Treatments
- Xenotransplantation and immune response
- Tissue Engineering and Regenerative Medicine
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac Ischemia and Reperfusion
- Venous Thromboembolism Diagnosis and Management
- Viral Infections and Immunology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Veterinary Equine Medical Research
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
Universität Hamburg
2014-2023
University Medical Center Hamburg-Eppendorf
2014-2023
Martini-Klinik
2017-2019
North Carolina State University
2013-2018
Deutsches Herzzentrum der Charité
2007-2015
Medical University of Vienna
2014-2015
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2011-2015
El.En. Group (Italy)
2011
University Cancer Center Hamburg
2010
Ludwig-Maximilians-Universität München
1998-2008
Abstract Objectives: We report our experience with transcatheter valve‐in‐valve implantations in patients degenerated bioprostheses aortic and mitral position. Background: Xenograft degeneration is a potential problem after biological valve replacement. Reoperation remains the gold standard very good short‐ long‐term results. In selected not suitable for surgery however, interventional techniques implantation repair may be valuable alternative treatment options regard to results of native...
Transcatheter aortic valve-in-valve implantation (ViV) is a new treatment for failing bioprostheses (BP) in patients with high surgical risk. However, comparative data, using standard repeat valve replacement (redo-SAVR), are scarce. We compared outcomes after ViV those conventional redo-SAVR two European centres established interventional programmes. In-hospital databases were retrospectively screened ≥60 years, treated BP. Cases of infective endocarditis or combined procedures excluded....
Animal organs could satisfy the demand for solid organ transplants, which currently exceeds limited human donor supply. Hyperacute rejection, initial immune barrier to successful xenotransplantation, has been overcome with pig donors transgenic complement regulatory proteins. Delayed xenograft thought be mediated by anti-pig antibodies predominantly Gal antigens, is regarded as major xenotransplantation. A median graft survival of 90 days in life-supporting position considered a reasonable...
Background. Calcineurin-inhibitor-(CNI)-induced renal failure is one major cause of morbidity in cardiac transplantation (HTx). In this prospective, randomized, multicenter trial, the impact immunosuppressive conversion toward CNI-free (mycophenolate mofetil [MMF] and sirolimus) or a CNI-reduced regimen on function, efficacy, safety was evaluated. Methods. Since 2004, 63 HTx-patients (0.5–18.4 years after HTx) with CNI-based immunosuppression reduced creatinine clearance less than 60 mL/min...
Objectives We report the results of a large single‐center study evaluating predictors and outcomes after transcatheter aortic valve implantation (TAVI) with different devices access routes according to Valve Academic Research Consortium (VARC). Background The widespread adoption TAVI warrants systematic analysis outcomes. Only few comprehensive data exist comparing approaches as selected by heart team. Methods was performed in 326 consecutive patients (mean age 80.6 ± 7.1 years, 55.5%...
Transcatheter aortic valve implantation (TAVI) has emerged rapidly. Despite unanimous recommendations and potentially fatal intraoperative complications, the heart-team approach is not comprehensively adopted by all centres. We sought to characterize severe intraprocedural complications during TAVI requiring immediate surgical or interventional bailout manoeuvres evaluate outcomes. was performed in 458 consecutive patients using a balloon-expandable self-expanding through transfemoral...
Purpose: The purpose of this study was to demonstrate polarization-sensitive optical coherence tomography (PS-OCT) for imaging pigmented structures in the posterior eye segments albino and rats correlate depolarization contrast retinal pigment epithelium (RPE) choroid vivo PS-OCT melanin pigmentation detected postmortem histologic serial sections. Methods: In three-dimensional performed adult rat eyes at 70-kHz A-line rate. Degree polarization uniformity (DOPU) fundus maps radial DOPU...
Objectives We sought to evaluate the relationship of blood transfusion after transcatheter aortic valve implantation (TAVI) and mid‐term outcome improve patient selection periprocedural treatment. Background Increasing evidence suggests a negative influence on outcomes patients with cardiovascular diseases. While adverse impact bleeding events survival has been documented TAVI, data postoperative transfusions are scarce. Methods TAVI was performed in 700 consecutive patients; 14.7% suffered...