A5101656547- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Immune cells in cancer
- Circadian rhythm and melatonin
- Flavonoids in Medical Research
- Coordination Chemistry and Organometallics
- Algal biology and biofuel production
- Gastric Cancer Management and Outcomes
- Organometallic Complex Synthesis and Catalysis
- Traditional Chinese Medicine Analysis
- Colorectal and Anal Carcinomas
- Viral Infections and Vectors
- Synthesis and characterization of novel inorganic/organometallic compounds
- Immune Cell Function and Interaction
- Cancer, Stress, Anesthesia, and Immune Response
- Pediatric health and respiratory diseases
- Ubiquitin and proteasome pathways
- Microbial Metabolic Engineering and Bioproduction
- interferon and immune responses
- Lipid metabolism and biosynthesis
- Cancer Research and Treatments
- Plant-based Medicinal Research
- Renal and Vascular Pathologies
- Autophagy in Disease and Therapy
- Neuroinflammation and Neurodegeneration Mechanisms
Xuzhou Medical College
2021-2023
Soochow University
2023
Soochow University
2023
Second Affiliated Hospital of Soochow University
2023
Jiangnan University
2021
Northwest University
2019-2020
Ministry of Education of the People's Republic of China
2019-2020
China XD Group (China)
2019
Hunan Children's Hospital
2016
Two Mg-Mg-bonded compounds were synthesized by using the ligands N,N'-bis(dipp)-phenanthrene-9,10-diimine (L2) and N,N'-bis(dipp)-o-phenylenediamine (H2L3; dipp = 2,6-diisopropylphenyl). These new Mg(i) species characterized X-ray diffraction, NMR, UV-Vis fluorescence spectroscopy, DFT computations. Their reactions with unsaturated organic molecules examined.
Metal–metal-bonded compounds containing low-valent metal centers have attracted much attention because of their novel structure and reactivity, while the proper choice ligands with suitable electronic steric properties is key to synthesis such species. Herein, we demonstrate that ortho-phenylene-diamine (dipp-H2pda, H2L) ligand upon deprotonation dianion (dipp-pda2–) can effectively stabilize a series E–E bonds, including group 12–15 elements Zn, Ga, Ge, P. In particular, Ge(I) compound in...
Stomach cancer is the fourth most common type of worldwide. TCN1 mainly encodes vitamin B12 transporter, transcobalamin. a marker gastrointestinal tumor progression, but impact on survival unclear.Gastrointestinal records were reviewed and analyzed, clinicopathological data summarized, immunohistochemical detection was performed again, protein expression in tissue, non-tumor lymph nodes semi-quantitatively analyzed. Patients followed up for 5 years to determine 5-year rates.The strong immune...
Introduction: The exosomes from adipose-derived mesenchymal stem cells (AMSCs) had therapeutic effects. However, whether the derived hypoxia-treated AMSCs could improve renal functions in unilateral ureteral obstruction (UUO) mice remains unclear. Methods: were characterized using a transmission electron microscope and Western blot. Its size distribution was determined Zetasizer Nano ZS analysis system. differentiation ability assessed by alkaline phosphatase oil red staining. Consequently,...
Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress, which subsequently triggers unfolded protein response (UPR) and autophagy, been shown facilitate survival tumor cells. The disruption circadian clock considered a characteristic feature cancer. how disrupted intertwines with metabolism drug resistance not clearly...
Objective To explore the influences of family-centered health education on compliance segregation in children with respiratory infectious disease. Methods The patients observation group received and included 247 disease who were hospitalized Hu′nan Children′s Hospital from August to December 2014 their parents. The control normal 285 January July parents compared between two groups. Results The cognition awareness, category requirement segregation, as well parents′ effective...
Although cGAS–STING signaling has been extensively studied to boost lymphocytes infiltration and tumor eradication. Since cGAS are rarely inactivated in cancer. It is not known why loss-of-function mutations do arise tumors. Here we discovered a cancer promoting role of DLBCL through IL6-STAT3 NF-κB signaling. Firstly, showed that was highly expressed both ABC GCB subtypes DLBCL. suppression DLBC cell lines induced cycle arrest, decreased proliferation rate apoptosis. knockdown lead growth...
Abstract Cancer cells compete with tumor associated macrophages for iron, especially drug resistant cells. But how immunosuppressive in microenvironment is unclear. Here, we identified the triggering receptor expressed on myeloid 2 (TREM-2) as a signaling hub that orchestrates lipid and iron metabolism, immune evasion. TREM-2 was only cisplatin gastric cancer cell lines, but not normal epithelial Suppressing TREM2 reversed resistance vitro slowed down growth vivo. Mechanically, facilitated...