A5102766536- Advanced Radiotherapy Techniques
- Gastric Cancer Management and Outcomes
- Cancer Immunotherapy and Biomarkers
- Cancer, Hypoxia, and Metabolism
- Radiation Therapy and Dosimetry
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Head and Neck Cancer Studies
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Cancer Research and Treatments
- Medical Imaging Techniques and Applications
- Pancreatic and Hepatic Oncology Research
- Cancer, Lipids, and Metabolism
- Soft tissue tumor case studies
- Cancer-related molecular mechanisms research
- Endometrial and Cervical Cancer Treatments
- Lung Cancer Diagnosis and Treatment
- Anatomy and Medical Technology
- Tracheal and airway disorders
- Esophageal Cancer Research and Treatment
- Metastasis and carcinoma case studies
- Diet, Metabolism, and Disease
- Brain Metastases and Treatment
First Affiliated Hospital of Zhengzhou University
2020-2025
Baylor Scott & White Health
2024
Baylor Scott & White Medical Center - Temple
2024
Chinese PLA General Hospital
2023
Affiliated Hospital of Hangzhou Normal University
2009-2022
Hangzhou Normal University
2022
Nanjing Medical University
2019-2022
National Medical Products Administration
2022
Chinese People's Liberation Army
2021
Soochow University
2011-2020
The aim of the present study was to investigate Toll-like receptor-4 (TLR4) signalling at different stages non-alcoholic fatty liver disease (NAFLD) induced by a high-fat, high-fructose (HFHFr) diet in mice. Both TLR4 wild-type (WT) and mutant (TLR4(mut) ) mice were fed either standard chow (SC) or HFHFr for periods time from 4 16 weeks. Pathological characteristics function assessed. Simple steatosis, steatohepatitis hepatic fibrosis occurred sequentially Week 4, 8 WT with HFHFr. Expression...
Endoscopic clamp biopsy is generally performed to confirm the pathological diagnosis of esophageal stenosis. However, it might be challenging in patients with severe Hence, we aimed investigate feasibility and safety interventional radiology-guided under fluoroscopy for diagnosing The clinical data 81 aged 39-89 (mean age 67.4 ± 10.5) years stenosis whose tissues were obtained by forceps at our treatment center retrospectively analyzed; 35.8% (29/81) had space-occupying 64.2% (52/81)...
Abstract Purpose The aim of the study was to compare dose differences between two kinds materials (silica gel and hydrogel) used prepare boluses based on three‐dimensional (3D) printing technologies commercial bolus in head phantoms simulating nose, ear, parotid gland radiotherapy. Methods We 3D technology make silica hydrogel boluses. To evaluate clinical feasibility, intensity modulated radiation therapy (IMRT) plans were created for that bolus‐free or had a bolus, bolus. Dosimetry...
Obstruction is a common complication of advanced colorectal cancer. This study was aimed at investigating the safety, efficacy, and feasibility transcatheter arterial perfusion chemotherapy combined with lipiodol chemoembolization for treating cancer complicated by obstruction.
Colorectal cancer (CRC) patients often exhibit peritoneal metastasis, which negatively impacts their prognosis. CD31 and D2-40 have recently been suggested to be predictors of breast prognosis, but role in colorectal metastasis (CRPM) remains unknown.The expression profiles were analyzed CRC with or without CRPM cell lines increasing metastatic potential. Overexpression short hairpin RNA knockdown assays performed cells, the effects these alterations on epithelial-mesenchymal transition...
Rationale: Molecular targeted therapy provides new ideas and hope for the treatment of hepatocellular cancer. Epidermal growth factor receptor (EGFR) is closely related to tumor cell proliferation, apoptosis, invasion, metastasis. Patient concerns: Several reports indicate that EGFR expressed frequently in carcinoma (HCC), thus targeting research has become a hot topic explore HCC patient. Diagnoses: Anti-EGFR might serve as potential therapeutic agent, especially patients with who are...
To investigate the correlation of serum osteoprotegerin (OPG) with progression nonalcoholic fatty liver disease (NAFLD) and noninvasive prediction diagnosis steatohepatitis (NASH).A total 136 patients NAFLD were enrolled, their tissue samples for biopsy obtained at 1 week after collected; 83 healthy subjects without symptoms proved by ultrasound examination enrolled as controls. The physiological indicators including height, body weight, waist circumference measured, mass index was...
Prognostic stratification in hepatocellular carcinoma (HCC) patients is still challenging. Long non-coding RNAs (lncRNAs) have been proven to play a crucial role tumorigenesis and progression of cancers. The aim this study develop useful prognostic index based on lncRNA signature identify at high risk disease progression. We obtained expression profiles from three publicly available datasets Gene Expression Omnibus (GEO) Cancer Genome Atlas (TCGA). By the scoring method, we built an...
Objectives Pancreatic cancer is the fourth leading cause of cancer-related death. Cryosurgery has emerged as a promising new technique for treatment. Although 80% pancreatic cancers are located in head, no research been conducted on safety and efficacy cryosurgery these tumors. Methods Two groups Tibetan miniature pigs (n = 4 per group) underwent to head with either deep freezing protocol (100% argon output) or shallow (10% output), compared sham-operated pigs. Results Serum inflammatory...
Aim: Advanced esophageal cancer has limited therapeutic options and a poor outcome. The efficacy of immunotherapy, as the first-line treatment advanced cancer, is uncertain. Results: A stage IV patient received with combination pembrolizumab chemotherapy. Partial response (PR) was achieved after three cycles, evaluated stable six cycles immunochemotherapy two maintenance monotherapy. Immune-related adverse events (irAEs) were not obvious. followed up till November 2019 when he died...
Stomach cancer is the fourth most common type of worldwide. TCN1 mainly encodes vitamin B12 transporter, transcobalamin. a marker gastrointestinal tumor progression, but impact on survival unclear.Gastrointestinal records were reviewed and analyzed, clinicopathological data summarized, immunohistochemical detection was performed again, protein expression in tissue, non-tumor lymph nodes semi-quantitatively analyzed. Patients followed up for 5 years to determine 5-year rates.The strong immune...
This paper proposes a novel load profiling method with the combination of firefly algorithm (FA-LP) for detecting abnormalities electricity customer. First, approach to model profile is proposed using data from similar customer in same region. Second, pattern extracted algorithm. Third, are processed differently and two matching measures adopted according different focuses on pattern. Finally, applied real case power supply company.
<title>Abstract</title> Purpose Gastric fundus and cardia cancer are increasingly common, diagnosed at a late stage, often with severe obstruction, have poor prognosis. Transcatheter arterial lipiodol chemoembolization (TACE) is rarely used for gastric cancer. This single-center retrospective study aimed to analyze the efficacy safety of transcatheter infusion chemotherapy (TAI) combined TACE in advanced obstruction compare it bland embolization (BE). Materials Methods The clinical TAI-TACE...
The aim of the present study was to compare radiotherapeutic plans based on internal target volume determined by between multiphase computed tomography and addition a generic margin in lung tumors evaluate reliability ITV during conventional fractionated radiotherapy.The 10 patients with were applied. difference two planning volumes (PTV) irradiated dose normal tissue compared. Weekly new targets delineated repeated scans, weekly coverage clinical under different treatment evaluated.For all...