- Shoulder Injury and Treatment
- Hip disorders and treatments
- Knee injuries and reconstruction techniques
- Sports injuries and prevention
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Shoulder and Clavicle Injuries
- Osteoarthritis Treatment and Mechanisms
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Diversity and Career in Medicine
- Cardiac Valve Diseases and Treatments
- Medical Education and Admissions
- Nerve Injury and Rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Foot and Ankle Surgery
- Bone and Joint Diseases
- Musculoskeletal Disorders and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Health Systems, Economic Evaluations, Quality of Life
- Musculoskeletal synovial abnormalities and treatments
- Dental Education, Practice, Research
- Athletic Training and Education
- Sport Psychology and Performance
- Bone fractures and treatments
University of California, San Francisco
2015-2025
Tulane University
2023
Oral Roberts University
2023
University of California San Francisco Medical Center
2021-2023
Rush University Medical Center
2019-2022
SUNY Downstate Health Sciences University
2022
Hospital for Special Surgery
2021
University of Pittsburgh
2021
Stanford University
2021
Osaka Health Science University
2021
Voltage-gated sodium channels (NaVs) are central elements of cellular excitation. Notwithstanding advances from recent bacterial NaV (BacNaV) structures, key questions about gating and ion selectivity remain. Here, we present a closed conformation NaVAe1p, pore-only BacNaV derived NaVAe1, the arsenite oxidizer Alkalilimnicola ehrlichei found in Mono Lake, California, that provides insight into both fundamental properties. The structure reveals pore domain which pore-lining S6 helix connects...
Background: Operative treatment of mechanical ankle instability is indicated for patients with multiple sprains and continued episodes instability. Open repair the lateral ligaments involves exposure attenuated advancement back to their anatomic insertions on fibula using bone tunnels or suture implants. Hypothesis: arthroscopic fixation are equal in strength failure Broström repair. Study Design: Controlled laboratory study. Methods: Seven matched pairs human cadaveric specimens were...
Many voltage-gated ion channel (VGIC) superfamily members contain six-transmembrane segments in which the first four form a voltage-sensing domain (VSD) and last two pore (PD). Studies of potassium channels from VGIC together with identification voltage-sensor only proteins have suggested that VSD PD can fold independently. Whether such transmembrane modularity is common to other has remained untested. Here we show, using protein dissection, Silicibacter pomeroyi sodium (Na(V)Sp1) forms...
To define the minimal clinically important difference (MCID), substantial clinical benefit (SCB) and patient-acceptable symptomatic state (PASS) for patient-reported outcome measures (PROMs) after medial patellofemoral ligament reconstruction (MPFLR) to investigate role of preoperative, demographic, intraoperative variables predicting achievement these thresholds.This retrospective cohort study used a prospectively maintained database patients undergoing primary MPFLR between August 2015...
<i>Purpose:</i> Collaborative goal-setting—with clinician and patient together deciding on concrete behavior-change goals—may be more effective in encouraging healthy behaviors than traditional clinician-directed advice. This study explores whether it is feasible for clinicians to engage patients with coronary heart disease (CHD) risk factors collaborative goal-setting action planning during the primary care visit. <i>Methods:</i> Primary were trained techniques asked conduct plan...
A series of six novel metallocenyl-7-ADCA (metallocenyl = ferrocenyl or ruthenocenyl; 7-ADCA 7-aminodesacetoxycephalosporanic acid) conjugates were synthesized and their antibacterial properties evaluated by biochemical microbiological assays. The ruthenocene derivatives showed a higher level inhibition DD-carboxypeptidase 64-575, Penicillin Binding Protein (PBP), than the ferrocene reference compound penicillin G. X-ray crystallographic analysis revealed covalent acyl-enzyme complex...
Background: Femoroacetabular impingement syndrome (FAIS) is frequently treated arthroscopically with osteoplasty and labral repair. Surgical preferences vary in terms of equipment, technique, postoperative protocol. Patient-reported outcome measures (PROMs) are valuable tools to assess outcomes across different institutions. Purpose: To compare PROMs after FAIS arthroscopy evaluate the impact on independent surgeons utilizing surgical techniques protocols. Study Design: Cohort study; Level...
Abstract Background: Femoroacetabular impingement syndrome (FAIS) is common in athletes, yet little understood about the effect of biomechanics and how they alter after hip arthroscopy. This study aimed to assess impact arthroscopy on biomechanical function patients with femoroacetabular during gait, stair ascent descent. Hypothesis: We hypothesized that symptomatic FAIS hips would exhibit decreased motion preoperatively compared contralateral hips, but these differences be corrected...
Abstract Purpose: The purpose of this study is to evaluate a large cross-sectional sample patients utilizing administrative database records, and analyze the effects income, insurance type, education level on outcomes after hip arthroscopy, including 2-year revision surgery, conversion total arthroplasty (THA) 90-day hospitalizations in United States. Methods: Current Procedural Terminology codes were used query PearlDiverTM Mariner from October 2015 January 2020 for undergoing arthroscopy...
Abstract Purpose: The purpose of this study is to determine whether response preoperative local anesthetic or corticosteroid intra-articular injections can predict 2-year postoperative outcomes in patients undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS). Methods: This was a retrospective analysis FAIS at single institution from 2014-2020. Patients who underwent injection were classified based on type (local anesthetic, corticosteroid) and they experienced pain...
Abstract Purpose: To analyze annual trends in hip arthroscopy (HA) and Bernese periacetabular osteotomy (PAO) for the treatment of dysplasia (HD), as well post-operative outcomes, including ipsilateral reoperations. Methods: Ninth Tenth Revision codes International Classification Diseases were used to query PearlDiver™ Mariner database from January 2010 through 2022 identify patients aged 10-59 years who had a presenting diagnosis HD subsequently underwent: 1) HA; 2) PAO; or 3) combined HA...