Souvik Das

ORCID: 0000-0003-2206-1990
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Hydrogels: synthesis, properties, applications
  • Prostate Cancer Treatment and Research
  • Epigenetics and DNA Methylation
  • Synthesis and Biological Evaluation
  • Synthesis and biological activity
  • Histone Deacetylase Inhibitors Research
  • Bone health and treatments
  • Genomics, phytochemicals, and oxidative stress
  • Advanced biosensing and bioanalysis techniques
  • PI3K/AKT/mTOR signaling in cancer
  • Genetic and Environmental Crop Studies
  • Parathyroid Disorders and Treatments
  • Transgenic Plants and Applications
  • Global Health and Epidemiology
  • Supramolecular Self-Assembly in Materials
  • Antioxidant Activity and Oxidative Stress
  • Multiple Myeloma Research and Treatments
  • Synthesis and Reactivity of Heterocycles
  • Plant Disease Resistance and Genetics
  • Dental Health and Care Utilization
  • Multicomponent Synthesis of Heterocycles
  • Polymer Nanocomposite Synthesis and Irradiation
  • Bone Metabolism and Diseases
  • Advanced Materials and Mechanics
  • Organometallic Compounds Synthesis and Characterization

Institute of Cancer Research
2024

Chittaranjan National Cancer Institute
2020-2023

All India Institute of Hygiene and Public Health
2021

Université de Picardie Jules Verne
2019-2020

Mécanismes physiopathologiques et conséquences des calcifications cardiovasculaires
2020

Amity University
2015-2017

Czech Academy of Sciences, Institute of Biotechnology
2015

Amity University
2015

Noida International University
2015

Gauhati University
1979

The transition metal complexes of Co(II), Ni(II), Cu(II) and Zn(II) with bidentate Schiff base ligands (HL 1−5 ) were obtained from condensation 1, 2, 3, 4‐tetrahydro‐naphthalen‐1‐ylamine methanolic solution 3‐hydroxy‐salicylaldehyde, 4‐hydroxy‐salicylaldehyde, 5‐bromo‐salicylaldehyde, 3,5‐dibromo‐salicylaldehyde, 2‐hydroxy‐1‐napthaldehyde. synthesized compounds structurally elucidated by spectral physical methods. characterization emphasized nature (NO) which gets chelated via nitrogen atom...

10.1002/aoc.6760 article EN Applied Organometallic Chemistry 2022-05-30

Introduction Natural carotenoids are well known for their anti-oxidant property and also shown to have antimicrobial anticancer efficacy. Production of from microbial resources mainly yeast has attracted commercial interest. Breast cancer the highest incidence among women, therapy resistance lack effective therapeutic strategies major treatment bottlenecks, particularly triple-negative subtypes. Yeast recently being evaluated affordable, non-toxic, natural product-based therapies. In present...

10.3389/fmicb.2022.1088477 article EN cc-by Frontiers in Microbiology 2023-01-18

Facile synthesis of physically cross-linked, pH responsive hydrogels as potential carriers for controlled drug delivery.

10.1039/c5ra07424j article EN RSC Advances 2015-01-01

The widespread use of potent androgen receptor signaling inhibitors (ARSIs) has led to an increasing emergence AR-independent castration-resistant prostate cancer (CRPC), typically driven by loss AR expression, lineage plasticity, and transformation cancers (PCs) that exhibit phenotypes neuroendocrine or basal-like cells. anti-apoptotic protein BCL2 is upregulated in may be a therapeutic target for this aggressive PC disease subset. There unmet clinical need, therefore, clinically...

10.1172/jci179998 article EN cc-by Journal of Clinical Investigation 2024-09-16

A novel approach used to synthesize antimetabolite-conjugated and intense blue fluorescence-emitting smart polymeric nanoparticles is reported for the efficient delivery of anticancer drugs self-monitoring their effect in drug-resistant metastatic breast cancer cells.

10.1039/d0ma00646g article EN cc-by-nc Materials Advances 2020-01-01

This is the first report of exploiting "quasi-spherical" shape water molecules for recapitulating a true human extracellular matrix (ECM). Herein, behaved as quasi-spherical porogen, engineering polysaccharide-rich and chemically defined 3D-microarchitecture, with semi-interpenetrating networks (S-IPNs). Furthermore, their viscoelastic behavior along heterogeneous, fibroporous morphology, facilitated instructive, self-remodeling bioartificial scaffolds, thence effectively permitting...

10.1021/acsami.0c01012 article EN ACS Applied Materials & Interfaces 2020-04-07

Oral health is a key indicator of overall and wellbeing. Despite adequate medical advancements in global oral health, problems still persist many communities India especially the hard to reach areas vulnerable population.This study aimed assess hygiene status among adults Santhal tribe rural area West Bengal find out factors associated with their status.A community-based, cross-sectional was conducted Paschim Bardhhaman district, Bengal. Data collected from 103 participants by simple random...

10.4103/jfmpc.jfmpc_2335_20 article EN Journal of Family Medicine and Primary Care 2021-08-27

Abstract Tetrazolo[1,5‐ a ]quinoline‐4‐carbaldehyde, 3‐oxo‐3‐phenylpropanenitrile, and β‐enamine were reacted in one‐pot to obtain highly functionalized quinolinyl‐1,4‐dihydropyridines. In addition spectroscopic characterization, the structure of one compound is confirmed by single‐crystal X‐ray diffraction. Among all compounds evaluated for cytotoxic effect against MCF7, three quinolinyl‐1,4‐dihydropyridines (SKS13, 19, 20) found be most active with half inhibition concentrations value...

10.1002/slct.202002612 article EN ChemistrySelect 2020-09-08

The structure of naturally occurring anhydrovitamin A2 was elucidated as 3-hydroxyanhydroretinol from study its u.v.–visible, i.r., n.m.r. and mass spectra. has been confirmed by a chemical synthesis. Saccobranchus fossils, freshwater fish, can convert 3-hydroxyretinol into 3-hydroxyanhydroretinol, which in turn is converted into-3-dehydroretinol. Chemical conversion 3-dehydroretinol also carried out.

10.1042/bj1770791 article EN Biochemical Journal 1979-03-01

In the short-season winter environment of India and Bangladesh, lentil growth seed yield are significantly hindered by foliar blight caused Stemphylium botryosum. As international germplasm pool lacks a resistance source, study aims to develop mutant population identify high-yielding against pathogen. A gamma-irradiated was developed based on its GR50 dose 248.8 Gy. The screening almost 130,000 M2 plants identified tolerant mutant, MM216. multi-location trials revealed that MM216 showed an...

10.1080/09553002.2024.2409667 article EN International Journal of Radiation Biology 2024-10-09

Abstract A series of novel pyrrole fused benzoxazinones/quinoxalinones has been evaluated for antiproliferative activity against breast cancer cell line, MCF7 and treatment‐resistant triple‐negative line MDA‐MB‐231. Among which pyrroloquinoxalinones exhibited higher cytotoxicity. Furthermore, they showed insignificant cellular cytotoxicity in normal human HEK293T when treated with their respective IC 50 concentrations. In silico molecular docking, study suggests that the inhibitory mechanism...

10.1002/slct.202103015 article EN ChemistrySelect 2021-10-25

Abstract Breast cancer is the most common form of affecting women worldwide with bones being prevalent site metastasis. The calcium sensing receptor (CaSR), whose primary physiological role homeostasis, has emerged as a new target in “vicious cycle” that amplifies metastatic cascade. Our team had already shown overexpression CaSR dramatically increased osteolytic potential MDA-MB-231 cells vivo. objective here was to study involvement metastasis breast bone using human femur tissue explants...

10.1158/1538-7445.am2019-2859 article EN Cancer Research 2019-07-01

Background:Post-natal depression, aserious mental health problem experienced by mothers 4 to 6 weeks after delivery. Patients suffering from post- natal depression are at higher risk of developing major depressive illness in future life. Objectives: To assess the prevalence post-natal and its associates among women a rural community Hooghly district, West Bengal. Methodology: A cross-sectional study was conducted 83 (period 6th 10th week delivery) Bengal, selected simple random sampling...

10.53553/jch.v09i01.007 article EN cc-by-nc-nd Journal of Comprehensive Health 2021-06-30
Coming Soon ...