A5102755811- Social Sciences and Governance
- Cultural Insights and Digital Impacts
- French Urban and Social Studies
- Plant and animal studies
- Ecology and Vegetation Dynamics Studies
- Species Distribution and Climate Change
- Evolution and Genetic Dynamics
- Animal Ecology and Behavior Studies
- Rangeland and Wildlife Management
- Ecosystem dynamics and resilience
- Insect and Pesticide Research
- Animal Behavior and Reproduction
- Insect and Arachnid Ecology and Behavior
- Peptidase Inhibition and Analysis
- Additive Manufacturing and 3D Printing Technologies
- Health, Medicine and Society
- Cephalopods and Marine Biology
- Environmental Conservation and Management
- Education, sociology, and vocational training
- Protein Tyrosine Phosphatases
- Healthcare Systems and Practices
- Genetic and Kidney Cyst Diseases
- Wildlife Ecology and Conservation
- Galectins and Cancer Biology
- 3D Printing in Biomedical Research
University Health Network
2020-2024
Princess Margaret Cancer Centre
2020-2024
UCLouvain
2016-2022
Abstract Accumulating evidence shows that landscape fragmentation drives the observed worldwide decline in populations of pollinators, particularly species Lepidoptera and Hymenoptera. However, Little is known about effects on hoverfly (Diptera, Syrphidae) communities. Hoverflies provide varied ecosystem services: larvae contribute to waste decomposition (saprophagous species) pest control (aphidophagous species), adults pollinate a wide range flowers. To determine how diversity quantity...
Significance In contrast to the classically expected coupling between ecological specialization and low dispersal propensity, theory predicts that with habitat choice (i.e., individuals choose habitats maximizing their performance) should evolve in specialists, while generalists disperse more randomly. Here, we show ciliate microcosms thermal specialists indeed prefer optimal habitats, whereas surprisingly, also perform but a preference for suboptimal habitats. To tackle question of why...
Abstract RAS-MAPK signaling mediates processes critical to normal development including cell proliferation, survival, and differentiation. Germline mutation of genes lead the Noonan-spectrum syndromes. Here, we present a patient affected by 6p-interstitial microdeletion with unknown underlying molecular etiology. Examination cases reveals shared clinical features consistent disorders short stature, facial dysmorphia cardiovascular abnormalities. We find RAS-responsive element binding...
Abstract Phenotypic plasticity is increasingly recognized as a key element of eco‐evolutionary dynamics, but it remains challenging to assess because its multidimensional nature. Indeed, organisms live in complex environments where numerous factors can impact the phenotypic expression traits (inter‐environment axis), possess multiple that influence each other's (inter‐trait axis) and differ their genetic background (inter‐genotype which not only traits' values also plasticity. We addressed...
Habitat fragmentation, the conversion of landscapes into patchy habitats separated by unsuitable environments, is expected to reduce dispersal among patches. However, its effects on should depend syndromes, i.e. how covaries with phenotypic traits, because these syndromes can drastically alter and subsequent ecological evolutionary dynamics. Our comprehension whether environmental factors such as habitat fragmentation generate and/or modify (i.e. conditional syndromes) therefore key for...
Abstract Organisms rarely experience a homogeneous environment. Rather, ecological and evolutionary dynamics unfold in spatially structured fragmented landscapes, with dispersal as the central process linking these across spatial scales. Because is multi-causal highly plastic life-history trait, finding general drivers that are of importance species challenging but relevant for forecasting. We here tested whether two fundamental forces main determinants local population dynamics, top-down...
Habitat fragmentation is expected to reduce dispersal movements among patches as a result of increased inter-patch distances. Furthermore, since habitat raise the costs moving in landscape, it should hamper ability or tendency organisms perform informed decisions. Here, we used microcosms ciliate Tetrahymena thermophila test experimentally whether fragmentation, manipulated through length corridors connecting differing temperature, affects choice. We showed that twofold increase distance can...
R2TP is a chaperone complex consisting of the AAA+ ATPases RUVBL1 and RUVBL2, as well RPAP3 PIH1D1 proteins. responsible for assembly macromolecular complexes mainly acting through different adaptors. Using proximity-labeling mass spectrometry, we identified deleted in primary ciliary dyskinesia (DPCD) an adaptor R2TP. Here, demonstrate that R2TP-DPCD influences ciliogenesis initiation unique mechanism by interaction with Akt kinase to regulate its phosphorylation levels rather than...
3D printing is described as the third industrial revolution: its impact global in industry and progresses every day society. It presents a huge potential for ecology evolution, sciences with long tradition of inventing creating objects research, education outreach. Its general principle an additive manufacturing technique relatively easy to understand: are created by adding material layers on top each other. Although this may seem very straightforward paper, it much harder real world....