Timothy V. Larson

ORCID: 0000-0003-2208-982X
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About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Air Quality Monitoring and Forecasting
  • Vehicle emissions and performance
  • Atmospheric chemistry and aerosols
  • Climate Change and Health Impacts
  • Noise Effects and Management
  • Energy and Environment Impacts
  • Atmospheric aerosols and clouds
  • Urban Transport and Accessibility
  • Odor and Emission Control Technologies
  • Atmospheric Ozone and Climate
  • Wind and Air Flow Studies
  • Atmospheric and Environmental Gas Dynamics
  • Health, Environment, Cognitive Aging
  • Advanced Chemical Sensor Technologies
  • Toxic Organic Pollutants Impact
  • Aeolian processes and effects
  • Urban Stormwater Management Solutions
  • Fire effects on ecosystems
  • Smart Materials for Construction
  • Energy, Environment, and Transportation Policies
  • Inhalation and Respiratory Drug Delivery
  • Neonatal Respiratory Health Research
  • COVID-19 impact on air quality
  • Sulfur Compounds in Biology

University of Washington
2016-2025

Office of Environmental Management
2020

Seattle University
1990-2018

Washington College
2013-2017

National Institute of Environmental Health Sciences
2017

Theodore Roosevelt High School
2014

University of California, Los Angeles
2006-2012

Tufts University
2006-2012

University of Southern California
2009

Desert Research Institute
2008

Recent studies have associated short-term exposure to respirable particulate matter (PM10) with peak flow decrements, increased symptoms of respiratory irritation, use asthma medications, and hospitalization for asthma. Increased mortality from chronic disease has also been reported. To help confirm whether PM10 is a risk factor the exacerbation asthma, we compiled daily records emergency room visits eight hospitals in Seattle area. In Poisson regressions controlling weather, season, time...

10.1164/ajrccm/147.4.826 article EN American Review of Respiratory Disease 1993-04-01

We measured fractional exhaled nitric oxide (FE(NO)), spirometry, blood pressure, oxygen saturation of the (SaO2), and pulse rate in 16 older subjects with asthma or chronic obstructive pulmonary disease (COPD) Seattle, Washington. Data were collected daily for 12 days. simultaneously PM10 PM2.5 (particulate matter < = 10 microm 2.5 microm, respectively) filter samples at a central outdoor site, as well outside inside subjects' homes. Personal also collected. All filters analyzed mass light...

10.1289/ehp.8153 article EN public-domain Environmental Health Perspectives 2005-08-25

The multivariate receptor models Positive Matrix Factorization (PMF) and Unmix were used along with the EPA's Chemical Mass Balance model to deduce sources of PM2.5 at a centrally located urban site in Seattle, WA. A total 289 filter samples obtained an IMPROVE sampler from 1996 through 1999 analyzed for 31 particulate elements including temperature-resolved fractions organic elemental carbon. All three predicted that major vegetative burning (including wood stoves), mobile sources,...

10.1021/es030370y article EN Environmental Science & Technology 2003-10-17

We assessed the relation between beta-carotene consumption at various times in life and breast cancer risk by conducting a case-control study nested within population-based cohort of women screened for Sweden. conducted telephone interview with 273 incident cases 371 controls about their diet ages throughout lifetime. Controls were frequency matched to on age, month year mammography, county residence. used unconditional logistic regression measure association intake while adjusting total...

10.1097/00001648-199901000-00006 article EN Epidemiology 1999-01-01

Most particulate matter (PM) health effects studies use outdoor (ambient) PM as a surrogate for personal exposure. However, people spend most of their time indoors exposed to combination indoor-generated particles and ambient that have infiltrated. Thus, it is important investigate the differential indoor- ambient-generated particles. We combined our recently adapted recursive model predictive estimating infiltration efficiency separate exposure (E) PM2.5 (PM with aerodynamic diameter ≤2.5...

10.1289/ehp.7511 article EN public-domain Environmental Health Perspectives 2005-01-10

The contribution of outdoor particulate matter (PM) to residential indoor concentrations is currently not well understood. Most importantly, separating PM into indoor- and outdoor-generated components will greatly enhance our knowledge the total personal exposures. This paper examines continuous light scattering data at 44 residences in Seattle, WA. A newly adapted recursive model was used outdoor-originated entering environments. After censoring time-series remove influence sources,...

10.1021/es021007e article EN Environmental Science & Technology 2003-07-11

Fine particle concentration (i.e., particles <2.5 microm in aerodynamic diameter; PM2.5), but not coarse concentration, was associated with increased mortality six U.S. cities. Others criticized this result, arguing that it could result from differences measurement error between the two size ranges. are primarily combustion of fossil fuel, whereras 2.5 and 10 diameter) all crustal material, i.e., dust. One way to determine if a risk for is identify episodes high concentrations coarse, fine,...

10.1289/ehp.99107339 article EN public-domain Environmental Health Perspectives 1999-05-01

We measured the spatial pattern of particle number (PN) concentrations downwind from Los Angeles International Airport (LAX) with an instrumented vehicle that enabled us to cover larger areas than allowed by traditional stationary measurements. LAX emissions adversely impacted air quality much farther reported in previous airport studies. at least a 2-fold increase PN over unimpacted baseline during most hours day area about 60 km(2) extended 16 km (10 miles) and 4- 5-fold 8-10 (5-6...

10.1021/es5001566 article EN publisher-specific-oa Environmental Science & Technology 2014-05-29

Snow samples obtained at 36 sites in Alaska, Canada, Greenland, Russia, and the Arctic Ocean early 2007 were analyzed for light-absorbing aerosol concentration together with a suite of associated chemical species. The light absorption data, interpreted as black carbon concentrations, other data input into EPA PMF 1.1 receptor model to explore sources snow. analysis found four factors or sources: two distinct biomass burning sources, pollution source, marine source. first three these...

10.1021/es803623f article EN Environmental Science & Technology 2009-04-29

Background: Epidemiologic studies of fine particulate matter [aerodynamic diameter ≤ 2.5 μm (PM2.5)] typically use outdoor concentrations as exposure surrogates. Failure to account for variation in residential infiltration efficiencies (Finf) will affect epidemiologic study results.Objective: We aimed develop models predict Finf > 6,000 homes the Multi-Ethnic Study Atherosclerosis and Air Pollution (MESA Air), a prospective cohort PM2.5 exposure, subclinical cardiovascular disease, clinical...

10.1289/ehp.1104447 article EN public-domain Environmental Health Perspectives 2012-02-22

The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air) was initiated in 2004 to investigate the relation between individual-level estimates long-term air pollution exposure progression subclinical atherosclerosis incidence cardiovascular disease (CVD). MESA builds on a multicenter, community-based US study CVD, supplementing that with additional participants, outcome measurements, state-of-the-art assessments fine particulate matter, oxides nitrogen, black carbon. More than...

10.1093/aje/kws169 article EN American Journal of Epidemiology 2012-10-04

Low-cost air monitoring sensors are an appealing tool for assessing pollutants in environmental studies. Portable low-cost hold promise to expand temporal and spatial coverage of quality information. However, researchers have reported challenges these sensors' operational quality. We evaluated the performance characteristics two widely used sensors, Plantower PMS A003 Shinyei PPD42NS, measuring fine particulate matter compared reference methods, developed regional calibration models Los...

10.1016/j.envint.2019.105329 article EN cc-by Environment International 2019-11-26

Exposure to traffic-related air pollution is associated with risk of cardiovascular disease and mortality. We examined whether exposure diesel exhaust increased blood pressure (BP) in human subjects. analyzed data from 45 nonsmoking subjects, 18 49 years age double-blinded, crossover studies, randomized order. Each subject was exposed exhaust, maintained at 200 μg/m 3 fine particulate matter, filtered for 120 minutes on days separated by ≥2 weeks. measured BP pre-exposure, 30-minute...

10.1161/hypertensionaha.111.186593 article EN Hypertension 2012-03-20
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