A5050836620- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Inflammatory Biomarkers in Disease Prognosis
- Respiratory Support and Mechanisms
- Acute Kidney Injury Research
- Neurosurgical Procedures and Complications
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Disaster Response and Management
- Hemodynamic Monitoring and Therapy
- Nosocomial Infections in ICU
- Tracheal and airway disorders
- Intracranial Aneurysms: Treatment and Complications
- Pneumonia and Respiratory Infections
- Kidney Stones and Urolithiasis Treatments
- Trauma Management and Diagnosis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pediatric Urology and Nephrology Studies
- COVID-19 and healthcare impacts
- Cytokine Signaling Pathways and Interactions
- Poisoning and overdose treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Acute Ischemic Stroke Management
Konkuk University Medical Center
2013-2024
Konkuk University
2013-2024
Inha University
2006
Pusan National University
2000
Non-small-cell lung cancer (NSCLC) is the most common subtype and accounts for more than 80% of all cases. Epidermal growth factor receptor (EGFR) phosphorylation by binding factors such as EGF activates downstream prooncogenic signaling pathways including KRAS-ERK, JAK-STAT, PI3K-AKT. These promote tumor progression NSCLC inducing uncontrolled cell cycle, proliferation, migration, programmed death-ligand 1 (PD-L1) expression. New cytotoxic drugs have facilitated considerable progress in...
Large language models (LLMs) have been deployed in diverse fields, and the potential for their application medicine has explored through numerous studies. This study aimed to evaluate compare performance of ChatGPT-3.5, ChatGPT-4, Bing Chat, Bard Emergency Medicine Board Examination question bank Korean language. Of 2353 questions bank, 150 were randomly selected, 27 containing figures excluded. Questions that required abilities such as analysis, creative thinking, evaluation, synthesis...
Cancer is one of the highly virulent diseases known to humankind with a high mortality rate. Breast cancer most common in women worldwide. Sorghum principal cereal food many parts world, and critical folk medicine Asia Africa. In present study, we analyzed effects HSE metastatic breast cancer.
Breast cancer is the most aggressive form of all cancers, with high incidence and mortality rates. The purpose present study was to investigate molecular mechanism by which methylsulfonylmethane (MSM) inhibits breast growth in mice xenografts. MSM an organic sulfur-containing natural compound without any toxicity. In this study, we demonstrated that substantially decreased viability human cells a dose-dependent manner. also suppressed phosphorylation STAT3, STAT5b, expression IGF-1R, HIF-1α,...
Purpose:In Korea, registration of paraquat-containing herbicides was canceled in November 2011, and sales thereof were completely banned 2012.We evaluated the effect paraquat ban on epidemiology mortality herbicide-induced poisoning.Materials Methods: This retrospective study analyzed patients treated for herbicide poisoning at 17 emergency departments South Korea between January 2010 December 2014.The overall rates compared pre-and post-ban.Factors associated with using logistic analysis.To...
Objectives: Hyperglycemia and hypokalemia are common problems in patients with aneurysmal subarachnoid hemorrhage (aSAH). The aim of this study was to determine whether the plasma glucose potassium ratio (GPR) predicts mortality due aSAH. Methods: We prospectively recruited aSAH healthy controls between March 2007 May 2017. Clinical outcomes included poor outcome (modified Rankin scale score 3-6) after 3 months. Multivariable analysis used association GPR 3-month patients. Results: A total...
This study evaluated whether measurements of plasma neutrophil gelatinase-associated lipocalin (NGAL) can predict acute kidney injury (AKI) in adult burn patients, and assessed the use this biomarker risk stratification. We performed a prospective observational consecutive patients with major burns admitted to center within 12 hours injury. Samples for NGAL assay were obtained three times (at admission, day 3, 7). The main outcome measures occurrence AKI based on Risk-Injury-Failure...
Background In upper gastrointestinal bleeding (UGIB) patients, early risk stratification allows appropriate therapy that may be helpful for reducing morbidity and mortality. Objectives to evaluate the efficacy of red-cell distribution width (RDW) prediction high-risk in UGIB patients. Methods We conducted a clinical retrospective observational study based on data patients from 2012 2013. The primary outcome was UGIB, defined as those who required urgent intervention and/or 30-days RDW...
This study investigated the effect of increasing numbers training sessions in cardiopulmonary resuscitation (CPR) on trainees' attitude and CPR quality.Cardiopulmonary for hospital employees was held every year from 2006 to 2010. Participants were recruited among trainees The attitudes toward surveyed by questionnaire, quality their measured using 5-cycle 30:2 a manikin. categorized according number consecutive as T1 (only 2010), T2 (2009 T3 (from 2008 2010) T4-5 or 2007 2010). trainee...
Objective To evaluate whether endotracheal intubation in patients with cervical spine immobilisation by a semirigid neck collar is easier using the Disposcope endoscope (DE), new video laryngoscope, than Macintosh laryngoscope (ML). Methods Sixty-eight medical interns who participated training programme for DE and ML were recruited to randomised crossover trial 1 week after completing programme. In trial, they used both perform on manikin wearing collar. The time required view vocal cords...
Objective To compare the efficacy of direct laryngoscopy (DL), Pentax Airway Scope (PAWS) and GlideScope video laryngoscope (GVL) systems for endotracheal intubation (ETI) in various cervical immobilisation scenarios: manual in-line stabilisation (MILS), Philadelphia neck collar (PNC) (moderate limit mouth opening) Stifneck (SNC) (severe opening). Design Randomised cross-over simulation study. Setting Participants 35 physicians who had >30 successful ETI experiences at a tertiary hospital...
The poisoning information database (PIDB) provides clinical toxicological on commonly encountered toxic substances in Korea. aim of this study was to estimate the coverage rate PIDB by comparing with distribution that real patients presented 20 emergency departments. Development started 2007, and number increased annually from 50 470 2014. We retrospectively reviewed medical records exposure who visited departments Korea January December 2013. Identified were classified as prescription drug,...
Acute kidney injury (AKI) is a common complication in patients with sepsis. We evaluated the potential prognostic value of plasma presepsin to predict AKI sepsis emergency department. A total 193 diagnosed based on Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) were included this observational study. was defined according Kidney Disease Improving Global Outcomes clinical practice guideline. Plasma levels measured admission compared between who did those not...