A5000155540- Engineering Applied Research
- Diverse Approaches in Healthcare and Education Studies
- Colorectal Cancer Screening and Detection
- Hair Growth and Disorders
- Gastric Cancer Management and Outcomes
- Rocket and propulsion systems research
- Genetic factors in colorectal cancer
- Education, Safety, and Science Studies
- Electromagnetic Launch and Propulsion Technology
- Electric and Hybrid Vehicle Technologies
- Vehicle emissions and performance
- Cancer and Skin Lesions
- Nail Diseases and Treatments
- Photonic and Optical Devices
- Ecology and Conservation Studies
- Acoustic Wave Resonator Technologies
- Healthcare and Venom Research
- Immunotherapy and Immune Responses
- Educational Systems and Policies
- Herpesvirus Infections and Treatments
- Mechanical Engineering and Vibrations Research
- Health and Wellbeing Research
- Innovation in Digital Healthcare Systems
- Neurosurgical Procedures and Complications
- China's Socioeconomic Reforms and Governance
University of Michigan
2024
Human Computer Interaction (Switzerland)
2024
Columbia University
2021-2024
Seoul National University
2012-2022
Seoul National University Hospital
2012-2022
Gyeongsang National University
2010-2018
CHA University
2002-2018
Konkuk University
2018
Boramae Medical Center
2013-2015
Inje University Busan Paik Hospital
2013
Abundant recent data suggest that sessile serrated adenoma/polyp (SSA/P) is an early precursor lesion in the pathway of carcinogenesis. It believed SSA/Ps develop cancer by SSA/P-dysplasia-carcinoma sequence. Hyperplastic polyps (HPs) share some histologic and molecular characteristics with SSA/P, but it unclear whether are derived from HPs or they a different pathogenetic pathway. Previous studies have shown Korean patients show prevalence rates certain abnormalities compared similar...
Bonding characteristics of low-dielectric-constant (low-k) fluorine-incorporated silicon oxide (SiOF) and carbon-incorporated (SiOC) films prepared by plasma enhanced chemical vapor deposition were investigated Fourier transform infrared spectroscopy (FTIR). The frequency Si–O stretching vibration mode in SiOF film shifted to higher wave number (blueshift) with the increase fluorine incorporation, while that SiOC lower (redshift) as carbon content increased. In N2-annealed film, slightly...
Preparation regimens for morning colonoscopy are suboptimal. The aim of this study was to test the efficacy and tolerance a split-dose magnesium citrate-low-volume (2 liters) polyethylene glycol (PEG) regimen colonoscopy.A total 232 patients were randomly assigned receive 4 liters PEG (day before procedure; group 1, n=79), 2 procedure) followed by another 2, n=80), or citrate (250 ml, day 3, n=73). quality bowel cleansing, tolerability, adverse effects in 3 compared with those groups 1...
Dermal fibroblasts lose stem cell potency after birth, which prevents regenerative healing. However, the underlying intracellular mechanisms are largely unknown. We uncover postnatal maturation of papillary (PFs) driven by extensive Twist2-mediated remodeling chromatin accessibility. A loss ability PFs occurs with decreased H3K27ac levels. Single-cell transcriptomics, assay for transposase-accessible sequencing (ATAC-seq), and immunoprecipitation (ChIP-seq) reveal trajectory associated in...
Abstract Ultraviolet (UV) exposure to the human skin reduces triglycerides contents and lipid synthesis in subcutaneous (SC) fat. Because adiponectin leptin are most abundant adipokines from SC fat, we aim investigate how they interact with UV aging. The expressions of were significantly decreased fat sun-exposed forearm skin, comparison that sun-protected buttock same elderly individuals, indicating chronic decreases both adipokines. Acute irradiation also receptor 1/2 dermis as well...
Abstract The maintenance of genetic integrity is critical for stem cells to ensure homeostasis and regeneration. Little known about how adult respond irreversible DNA damage, resulting in loss regeneration humans. Here, we establish a permanent model using cycling human hair follicles treated with alkylating agents: busulfan followed by cyclophosphamide. We uncover the underlying mechanisms which follicle (HFSCs) lose their pool. In contrast immediate destructive changes rapidly...
Blue rubber bleb nevus syndrome (BRBNS) is a rare systemic vascular disorder characterized by multiple venous malformations involving many organs. BRBNS can occur in various organs, but the most frequently involved organs are skin and gastrointestinal (GI) tract. GI lesions of cause acute or chronic bleeding, treatment challenging. Herein, we report case that was successfully treated with combination intraoperative endoscopy radical resection.
Abstract Background Dermatological patients do visit the emergency department (ED) while most skin problems are controllable in outpatient clinic. However, there is paucity of data on conditions presenting ED. Objective The aim this study was to provide demographic and clinical dermatological ED a secondary hospital Korea. Methods A retrospective conducted based international classification diseases (ICD) rendered Seoul National University Boramae Hospital, Seoul, Korea, during an 8‐year...
Acral lentiginous melanoma (ALM) is the most common type of cutaneous in Asian populations. Traditionally, ALM was believed to have a poorer prognosis than other subtypes because its aggressive behavior. However, Asians, there been several unusual case reports that shown only subtle melanocytic proliferation despite clinically malignant manifestations. We performed retrospective study 13 patients with ALM. reviewed clinical histories, histopathologies, and immunohistochemical staining from...
Background:The efficacy of the long-pulsed diode laser (LPDL) in hair removal is determined with various physical parameters.Recently, LPDLs a larger spot size are commercially available; however, independent effect on has not been studied.Objective:This study aimed to compare LPDL depending size.Methods: A randomized, evaluators-blind, intrapatient comparison (left vs. right) trial was designed.Ten healthy Korean women received three treatment sessions both armpits 805-nm and followed for 3...
Abstract Senescent cells secrete a senescence‐associated secretory phenotype (SASP), which can induce senescence in neighboring cells. Human dermal papilla (DP) lose their original hair inductive properties when expanded vitro , and rapidly accumulate senescent culture. Protein RNA‐seq analysis revealed an accumulation of DP‐specific SASP factors including IL‐6, IL‐8, MCP‐1, TIMP‐2. We found that combined senolytic treatment dasatinib quercetin depleted cells, reversed SASP‐mediated...
Alopecia induced by aging or side effects of medications affects millions people worldwide and impairs the quality life; however, there is a limit to current medications. Here, we identify small transdermally deliverable 5-mer peptide (GLYYF; P5) that activates adiponectin receptor 1 (AdipoR1) promotes hair growth. P5 sufficiently reproduces biological effect protein via AMPK signaling pathway, increasing expression growth factors in dermal papilla cells human follicle. accelerates ex vivo...
It is uncertain if a patient's lamivudine response after HBeAg loss durable. In Korean chronic hepatitis B patients, the relapse rate high termination of therapy for patients with loss. We evaluated factors related to in therapy.A total 132 who initially had and did not have decompensated features, were analyzed this study. These lost then their was stopped. Post-treatment serum alanine aminotransferase (ALT), HBeAg, anti-HBe virus (HBV) DNA monitored until relapse.Seventy-five relapsed...
Pincer nails are characterized by the transverse curvature increasing from proximal to distal aspect along longitudinal axis. A novel treatment technique using a shape memory alloy device was recently introduced.To determine outcomes and safety of device.This retrospective analysis 21 cases pincer nail great toe in 14 patients. Subjective indices (pain, inconvenience, global assessment scores) objective parameters (transverse angle, width index) on days 0 (D0) 1 (D1) weeks 2 (W2) 12 (W12)...