A5100360892- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- MRI in cancer diagnosis
- Thyroid Cancer Diagnosis and Treatment
- AI in cancer detection
- Head and Neck Anomalies
- Radiomics and Machine Learning in Medical Imaging
- Cancer and Skin Lesions
- High-Temperature Coating Behaviors
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Global Cancer Incidence and Screening
- Thyroid and Parathyroid Surgery
- Digital Radiography and Breast Imaging
- Pancreatic and Hepatic Oncology Research
- Breast Implant and Reconstruction
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Ultrasound Imaging and Elastography
- HER2/EGFR in Cancer Research
- Education and Learning Interventions
- Cancer Diagnosis and Treatment
- Photoacoustic and Ultrasonic Imaging
- Educational Systems and Policies
Yonsei University
2016-2025
Korea Food Research Institute
2012-2025
Seoul National University Hospital
2016-2025
Ajou University
2000-2025
Sungkyunkwan University
2015-2025
Hallym University Sacred Heart Hospital
2006-2025
Seoul Metropolitan Government
2021-2025
Boramae Medical Center
2021-2025
Duke University
2025
Seoul National University Bundang Hospital
2025
Preoperative Staging of Papillary Thyroid Carcinoma: Comparison Ultrasound Imaging and CTJi Soo Choi1, Jinna Kim1, Jin Young Kwak1, Min Jung Hang Seok Chang2 Eun-Kyung Kim1Audio Available | Share
Purpose To retrospectively evaluate the diagnostic performance of power Doppler ultrasonography (US) in depicting vascularity and to determine whether combination suspicious gray-scale US features is more useful predicting thyroid malignancy than are alone. Materials Methods This was an institutional review board-approved retrospective study, with waiver informed consent. A total 1083 nodules 1024 patients (median age, 51 years; range, 16–83 years), consisting 886 women 50 years) 138 men 53...
<h3>Importance</h3> Ovarian cancer has the highest mortality rate among gynecologic malignant tumors. Data are lacking on survival benefit of hyperthermic intraperitoneal chemotherapy (HIPEC) in women with ovarian who underwent primary or interval cytoreductive surgery. <h3>Objective</h3> To assess clinical HIPEC after maximal surgery stage III IV advanced cancer. <h3>Design, Setting, and Participants</h3> In this single-blind randomized trial performed at 2 institutions South Korea from...
Autosomal-recessive juvenile parkinsonism (AR-JP) is caused by loss-of-function mutations of the parkin gene. Parkin, a RING-type E3 ubiquitin ligase, responsible for ubiquitination and degradation substrate proteins that are important in survival dopamine neurons Parkinson's disease (PD). Accordingly, abnormal accumulation neurotoxic substrates attributable to loss function may be cause neurodegeneration parkin-related parkinsonism. We evaluated known identified date null mice determine...
Thyroid ultrasound (US) is used as the first diagnostic tool to assess management of disease. In spite its importance, US a very subjective method and highly dependent on skill performer. There have been few reports evaluating thyroid performance even fewer observer variability in assessment. Therefore, we evaluated inter- intraobserver variations assessment nodules diagnosis among four radiologists estimated accuracy.A total 204 144 patients were reviewed. 89 benign 115 malignant cases....
The objective of our study was to investigate interobserver agreement for the diagnosis malignant thyroid nodules using conventional B-mode ultrasound and real-time freehand elastography.Between December 2007 February 2008, 45 patients (age range, 19-73 years; mean age +/- SD, 45.0 12.2 years) with 52 were examined elastography. All scheduled undergo surgery because a nodule had been proven on aspiration cytology. Three radiologists independently performed elastography analyzed images. Using...
Fine-needle aspiration (FNA) biopsy of thyroid nodules is minimally invasive and safe usually performed on an outpatient basis. However, the optimal application FNA requires not only technical skill but also awareness limitations procedure, indications for its use, factors that affect adequacy specimen, postprocedural management strategy. Ultrasonographic (US) features are considered include single multiple nodules. The results operator dependent. In addition, may be affected by lesion...
Several studies report that detection of thyroglobulin (Tg) in fine-needle aspiration (FNA) biopsy washout fluid from lymph nodes identifies recurrences/metastases differentiated papillary thyroid cancer (DPTC) the neck with higher sensitivity and specificity than cytology (FNAC). However, diagnostic FNA-Tg cutoff values have not yet been established.To determine an appropriate threshold value for Tg levels FNA patients node metastases or recurrences DPTC.We performed ultrasound (US)-guided...
The purpose of this article is to evaluate the interobserver variability elastography on real-time ultrasound and how it influences agreement final assessment ultrasound.From April May 2009, 65 breast lesions 53 patients (mean age, 42.6 years; range, 18-72 years) who underwent ultrasound-guided core biopsy were included in study. Ultrasound images lesion subjected obtained prospectively analyzed by three radiologists with individual image scanning prior biopsy. Each radiologist recorded...
Clinical Application of the BI-RADS Final Assessment to Breast Sonography in Conjunction with MammographyEun-Kyung Kim1, Kyung Hee Ko1, Ki Keun Oh1, Jin Young Kwak1, Jai You1, Min Jung Kim1 and Byoung-Woo Park2Audio Available | Share
To investigate the value of ultrasonographic (US) features in thyroid nodules with initially benign cytologic results.The institutional review board approved this retrospective study and required neither patient approval nor informed consent for images records. From October 2003 to February 2006, 6118 focal 6025 consecutive patients underwent US-guided fine-needle aspiration biopsy (FNAB). This included 1343 1 cm or larger 1302 that were diagnosed as at initial evaluation pathologic...
Abstract Background This study evaluated the efficacy and safety of S-1 combined with docetaxel (SD) following doxorubicin plus cyclophosphamide (AC) as neoadjuvant therapy in patients HER2-negative, stage II-III breast cancer. Methods Patients received AC every 3 weeks for four cycles followed by (30 mg/m 2 orally b.i.d. on days 1–14) (75 i.v. day 1) cycles. The primary endpoint was pathological complete response (pCR) rate axillary lymph nodes. Results included 49 a median age 43 years....
Recent studies have revealed that microRNAs (miRs) play important roles in the regulation of angiogenesis. In this study, we characterized miR-382 upregulation by hypoxia and functional relevance tumor miRs induced MKN1 human gastric cancer cells were investigated using miRNA microarrays. We selected found expression was regulated HIF-1α. Conditioned media (CM) from transfected with a inhibitor (antagomiR-382) under hypoxic conditions significantly decreased vascular endothelial cell (EC)...
Objective: Harm-minimization policies suggest that alcohol use is a part of normal adolescent development and parents should supervise their children's to encourage responsible drinking. Zero-tolerance all underage be discouraged. This article compared hypotheses derived from harm-minimization zero-tolerance regarding the influence family context supervised drinking on related harms among adolescents in Washington State, USA, Victoria, Australia, two states have respectively adopted...
In 2017, the American Joint Committee on Cancer announced 8th edition of its cancer staging system.For breast cancer, most significant change in system is incorporation biomarkers into anatomic to create prognostic stages.Different stages are assigned tumors with same according tumor grade, hormone receptor (estrogen receptor; progesterone receptor) status, and HER2 status.A Clinical Prognostic Stage all patients regardless type therapy used; contrast, a Pathologic Prognosis whom surgery...
In women with a personal history of breast cancer, postoperative surveillance MRI was associated lower odds advanced second cancer before and after propensity score matching.
ABSTRACT Background The removal of preformed antibodies with cleaving enzymes like IdeS (imlifidase) has demonstrated therapeutic potential in organ transplantation for sensitized recipients. However, xenoreactive (XAbs) against porcine glycans are predominantly IgM and considered detrimental pig‐to‐human xenotransplantation. Methods Recombinant IceM, an endopeptidase IgM, was generated Escherichia coli ( E. ). Four maximally MHC‐mismatched rhesus macaques underwent two serial skin...