A5050306150- Heart Rate Variability and Autonomic Control
- Bariatric Surgery and Outcomes
- Diabetes Management and Research
- Blood Pressure and Hypertension Studies
- Bone health and osteoporosis research
- Cardiovascular Disease and Adiposity
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Bone and Dental Protein Studies
- Diabetes and associated disorders
- Gestational Diabetes Research and Management
- Diet and metabolism studies
- Nutrition and Health in Aging
- Vitamin D Research Studies
- Cardiovascular and exercise physiology
- Lymphoma Diagnosis and Treatment
- Pain Mechanisms and Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Clusterin in disease pathology
- Botulinum Toxin and Related Neurological Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Biomarkers in Disease Mechanisms
- Parathyroid Disorders and Treatments
- Body Contouring and Surgery
- Neuroscience of respiration and sleep
Christiana Care Health System
2008-2024
Thomas Jefferson University
2001-2024
University of Delaware
2007-2013
Philadelphia University
2013
RELX Group (United States)
2013
Justus-Liebig-Universität Gießen
2006-2011
Klinik für Frauenheilkunde
2009
Saint Francis University
2001
Saint Francis Hospital
2001
Wilmington VA Medical Center
1998
Summary Patients with refractory or early relapsed anaplastic large cell lymphoma (ALCL) have a poor chance of survival. We report 20 children and adolescents high‐risk ALCL who underwent allogeneic haematopoietic stem transplantation (HSCT). retrospectively analysed patients between December 1991 April 2003 during (six patients) soon after first‐line Berlin–Frankfurt–Münster‐type chemotherapy (14 HSCT. Nine received HSCT the first relapse 11 multiple relapses. Eight their transplants from...
To evaluate risk factors for outcome in children and adolescents with relapse of anaplastic large-cell lymphoma (ALCL) after comparable first-line therapy.We analyzed a population-based cohort 74 relapsed ALCL Berlin-Frankfurt-Muenster-type therapy between April 1990 December 2003. The recommended salvage strategy was reinduction chemotherapy followed by autologous hematopoietic stem-cell transplantation (SCT).With median follow-up time 8.4 years (range, 4.5 to 16.4 years), the 5-year...
Abstract Objective: To determine the impact of surgically induced weight loss on cardiovascular autonomic function in subjects with severe obesity and examine whether effect was comparable for persons without diabetes. Research Methods Procedures: Twenty‐six severely obese individuals (BMI = 48 ± 7 kg/m 2 ) underwent bariatric surgery (laparoscopic Roux‐en‐Y gastric bypass, n 21; laparoscopic adjustable banding, 5). Cardiovascular (heart rate variation during deep breathing Valsalva...
To examine the relationship between Zn nutritive status and biochemical markers of bone turnover in type 1 diabetes.Serum osteocalcin, urine N-telopeptides, dietary intake data, obtained by 3-day food records, were assessed for 66 individuals with diabetes.Zn correlated osteocalcin group overall (r = 0.48; P < 0.001) but not N-telopeptides. Examined sex, both men 0.57; 0.001), correlation did reach statistical significance women 0.34; 0.09). A direct-entry linear regression model as...
Purpose: Surgical treatment for primary hyperparathyroidism (PHPT) improves bone metabolism. Osteocalcin (OC) and its undercarboxylated form (ucOC) are associated with energy Osteopontin (OPN), a multifunctional protein expressed in bone, is involved resorption, along β-carboxyl-terminal cross-linking telopeptide of type 1 collagen (β-CTX), osteoprotegerin (OPG). Our aim was to investigate these biomarkers metabolism patients PHPT. Methods: We examined 30 individuals PHPT, clinical research...
Lipoprotein lipase (LPL) is a major enzyme in lipid metabolism. Dyslipidemia, characterized by decreased high-density lipoprotein cholesterol (HDL-C), prevalent persons with type 2 diabetes mellitus (T2DM). The aim of this study was to determine whether pre-heparin LPL mass mediates the association between adiponectin and HDL-C individuals T2DM.Pre-heparin measured via an enzyme-linked immunosorbent assay, radioimmunoassay, determined enzymatically. Participants' (n = 50) demographics,...
The renin-angiotensin-aldosterone system (RAAS) and autonomic nervous regulate the cardiovascular system. Blockade of RAAS may slow progression end-organ damage. Direct renin inhibition offers a means for blocking RAAS. objective this study was to examine effect direct on function.In double-blind, placebo-controlled trial, 60 individuals with diabetes were randomly assigned 300 mg aliskiren or placebo once daily 6 weeks. primary end point change in tests function. Autonomic function assessed...
This study examined the dynamic, real-time associations between partner involvement in diabetes self-care and continuous glucose monitor (CGM) metrics adults with type 2 diabetes.
Aim: Cardiovascular autonomic neuropathy is a serious complication of diabetes mellitus. Previous studies have revealed conflicting results with regard to the role obesity and its effect on performance tests (e.g. RR‐variation during deep breathing) for determination presence cardiovascular dysfunction. The objective this study was determine if affects reproducibility function tests. Methods: This cross‐sectional included 159 diabetic individuals. Autonomic included: breathing Valsalva...