A5083515644- Mesenchymal stem cell research
- Osteoarthritis Treatment and Mechanisms
- Wound Healing and Treatments
- Birth, Development, and Health
- Circadian rhythm and melatonin
- Cardiovascular and Diving-Related Complications
- Air Quality and Health Impacts
- RNA Interference and Gene Delivery
- Inflammatory Bowel Disease
- Fluoride Effects and Removal
- Curcumin's Biomedical Applications
- Nigella sativa pharmacological applications
- Oral and gingival health research
- Poisoning and overdose treatments
- Ginger and Zingiberaceae research
- Tendon Structure and Treatment
- Electrospun Nanofibers in Biomedical Applications
- Pharmacological Effects and Toxicity Studies
- Medical and Biological Ozone Research
- Nanoparticle-Based Drug Delivery
- Antioxidant Activity and Oxidative Stress
Cairo University
2015-2025
Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality life. Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use in treatment RA. Similarly, interleukin (IL)-4 has been shown as potential RA treatment. However, their combination not explored before. Therefore, this study aimed to investigate effect therapy MSCs and IL-4 RA, using murine collagen-induced (CIA) model. Arthritis was induced Balb/c mice by two intradermal injections...
Liver cancer is a prevalent form of carcinoma worldwide. A novel chitosan-coated optimized formulation capped with irradiated silver nanoparticles (INops) was fabricated to boost the anti-malignant impact rosuvastatin calcium (RC). Using 23-factorial design, eight formulations were produced using solvent evaporation process. The characterized in vitro identify optimal (Nop). FTIR spectra showed that fingerprint region not superimposed drug; DSC thermal analysis depicted negligible peak...
Wound healing involves the integration of complex biological processes. Several studies examined numerous approaches to enhance wound and minimize its related morbidity. Both chitosan mesenchymal stem cells (MSCs) were used in treating skin wounds. The aim current work was compare MSCs versus healing, evaluate most efficient route administration MSCs, either intradermal or systemic injection, elicit mechanisms inducing epidermal dermal cell regeneration using histological,...
The present study was conducted to investigate the role of vitamin C versus platelet-rich plasma (PRP) against sodium fluoride (NaF)-induced cardiotoxicity and cell death in rats' myocardium. Previous studies suggest that NaF decreased cellular viability intracellular antioxidant power.The revealed administration caused histological alterations cardiac muscle increased accumulation reactive oxygen species, expression inducible nitric oxide synthases proliferating nuclear antigen as well...
Although the risks of smoking are well known, effects exposure to nicotine on endocrine functions remain unclear. We investigated deleterious adrenal gland and mechanisms these changes in rats. The role melatonin ameliorating pathological also was investigated. used 24 rats divided into four groups six: group 1, control; 2, treated; 3, 4, treated. histology; immunohistochemistry inducible nitric oxide synthase (iNOS), vascular endothelial growth factor (VEGF) tyrosine hydroxylase (TH);...
Through scientific literature, there is evidence that light affects thyroid function in human, mice and rabbits. Constant sleep deprivation also used as a form of human torture, it has impact on cognitive performances. The present work was conducted to study the effect constant for short long periods gland prepubertal male albino rats.A total 30 rats were used. separated into three groups: group I (control); II those put under steady encompassing (24 h/day, intensity 600 lux) 4 weeks; III...
Background: Idiopathic Inflammatory bowel diseases remain chronic progressive major health problem with no effective line of treatment.The aim this work is to study the protective effects both N. acetylcysteine (NAC) and ginger in acetic acid induced colitis model. Material methods:Fifty adult male Sprague Dawley albino rats were divided into five groups: control group (GI), II (GII); performed by giving 4% intrarectally, III (GIII); NAC treated from colitis, IV (GIV); Ginger V (GV);...