A5003636856- Advanced X-ray and CT Imaging
- Epilepsy research and treatment
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Inflammatory Bowel Disease
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Pediatric Urology and Nephrology Studies
- Ultrasound Imaging and Elastography
- MRI in cancer diagnosis
- Fetal and Pediatric Neurological Disorders
- Pharmacological Effects and Toxicity Studies
- Autoimmune and Inflammatory Disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Immunotherapy and Biomarkers
- Microscopic Colitis
- Glioma Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Artificial Intelligence in Healthcare and Education
- Lymphadenopathy Diagnosis and Analysis
- Liver Disease Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Cardiac tumors and thrombi
University Children's Hospital Zurich
2021-2025
University of Zurich
2021-2024
University Hospital of Zurich
2021-2024
Fondazione IRCCS Istituto Neurologico Carlo Besta
2018-2023
Hospital de Sant Pau
2021
Ospedale di Cattinara
2010-2020
University of Trieste
2010-2020
Ospedale San Paolo
2020
European Institute of Oncology
2018
Johns Hopkins University
2018
To assess the frequency, intensity, and clinical impact of [18F]FDG-avidity axillary lymph nodes after vaccination with COVID-19 vaccines BNT162b2 (Pfizer-BioNTech) mRNA-1273 (Moderna) in patients referred for oncological FDG PET/CT.One hundred forty PET/CT during February March 2021 first or second Pfizer-BioNTech Moderna were retrospectively included. FDG-avidity ipsilateral was measured compared. Assuming no knowledge prior vaccination, metastatic risk analyzed by two readers...
Sonoelastography is an ultrasound imaging technique able to assess mechanical properties of tissues. Strain elastography (SE) a qualitative sonoelastographic modality with wide range clinical applications, but its use in brain tumor surgery has been so far very limited.To describe the first large-scale implementation SE oncological neurosurgery for lesions discrimination and characterization.We analyzed retrospective data from 64 patients aiming at (i) evaluating stiffness lesion surrounding...
Abstract Poor sleep quality might contribute to the risk and progression of neurodegenerative disorders via deficient cerebral waste clearance functions during sleep. In this retrospective cross-sectional study, we explore link between enlarged perivascular spaces (PVS), a putative marker sleep-dependent glymphatic clearance, with motor symptoms in patients Parkinson’s disease (PD). T2-weighted magnetic resonance imaging (MRI) images 20 17 healthy control participants were estimated visually...
Purpose To assess whether contrast material-enhanced ultrasonography (US) can be used to differentiate responders from nonresponders among patients with clinically active Crohn disease after 6 weeks of pharmacologic treatment. Materials and Methods This prospective study was approved by our ethics committee, written informed consent obtained all patients. Fifty consecutive (26 men 24 women; mean age, 34.76 years ± 9) a proved diagnosis who were scheduled begin therapy biologics (infliximab...
Abstract Arterial spin labelling (ASL), an MRI sequence non-invasively imaging brain perfusion, has yielded promising results in the presurgical workup of children with focal cortical dysplasia (FCD)-related epilepsy. However, interpretation ASL-derived perfusion patterns remains unclear. Hence, we compared ASL qualitative and quantitative findings to their clinical, EEG, counterparts. We included structural epilepsy related MRI-detectable FCD who underwent single delay pseudo-continuous...
Abstract It has been suggested that the inferior longitudinal fasciculus (ILF) may play an important role in several aspects of language processing such as visual object recognition, memory, lexical retrieval, reading, and specifically, naming stimuli. In particular, ILF appears to convey information from occipital lobe anterior temporal (ATL). However, direct evidence proving essential semantics remains limited controversial. The first aim this study was prove patients with a brain glioma...
Abstract Objective This study was undertaken to determine whether integrating arterial spin labeling (ASL) perfusion imaging into presurgical planning improves postsurgical seizure outcomes in children with pharmacoresistant focal lesional epilepsy associated cortical dysplasia (FCD) or low‐grade epilepsy‐associated tumors (LEATs). Methods We retrospectively analyzed magnetic resonance (MRI) scans from 18 (median age = 4.8 years, interquartile range 1.9–11.5) who underwent resection for FCD‐...
High-frequency oscillations (HFO) in scalp EEG are a new and promising noninvasive epilepsy biomarker, providing added prognostic value, particularly pediatric lesional epilepsy. However, it is unclear if lesion characteristics, such as volume, depth, type, localization, impact HFO rates. We analyzed from 13 children adolescents with focal associated cortical dysplasia (FCD), low-grade tumors, or hippocampal sclerosis. applied validated automated detector to determine rates bipolar channels....
Although diffusion tensor imaging (DTI) may facilitate the identification of cytoarchitectural changes associated with focal cortical dysplasia (FCD), predominant aetiology paediatric structural epilepsy, its potential has thus far remained unexplored in this population. Here, we investigated whether DTI indices can differentiate FCD from contralateral brain parenchyma (CBP) and clinical features affect these indices.In single-centre, retrospective study, considered children adolescents...
Abstract Microbubbles (MB) are widely used as contrast agents to perform contrast-enhanced ultrasound (CEUS) imaging and acoustic amplifiers of mechanical bioeffects incited by therapeutic-level ultrasound. The distribution MBs in the brain is not yet fully understood, thereby limiting intra-operative CEUS guidance or MB-based FUS treatments. In this paper we describe a robust platform for quantification MB human brain, allowing quantitatively discriminate between tumoral normal tissues...
Abstract Epilepsy surgery can achieve seizure freedom in selected pediatric candidates, but reliable postsurgical predictors of are missing. High frequency oscillations (HFO) scalp EEG a new and promising biomarker treatment response. However, it is unclear if the skull defect resulting from craniotomy interferes with HFO detection recordings. We considered 14 children focal lesional epilepsy who underwent presurgical evaluation, surgery, follow-up ≥ 1 year. identified nearest electrodes to...
To assess the accuracy of fully automated deep learning (DL) based coronary artery calcium scoring (CACS) from non-contrast computed tomography (CT) as acquired for attenuation correction (AC) cardiac single-photon-emission myocardial perfusion imaging (SPECT-MPI). Patients were enrolled in this study part a larger prospective (NCT03637231). In study, 56 who underwent SPECT-MPI due to suspected disease (CAD) prospectively enrolled. All patients CT AC twice. CACS was manually assessed...
Malignant mesothelioma is doubtless the more known pleural tumour. However, according to morphology code of International Classification Diseases for Oncology (ICD-O), there are several histological types neoplasms, divided into mesothelial, mesenchymal and lymphoproliferative tumours, that may be misdiagnosed. In this paper we summarise illustrate incidence aspects clinical, pathological radiological features these neoplasms. • According ICD-O, 11 different neoplasm. Imaging, clinical...
Segmentation is a critical step in analyzing the developing human fetal brain.There have been vast improvements automatic segmentation methods past several years, and Fetal Brain Tissue Annotation (FeTA) Challenge 2021 helped to establish an excellent standard of brain segmentation.However, FeTA was single center study, generalizability algorithms across different imaging centers remains unsolved, limiting real-world clinical applicability.The multi-center 2022 focuses on advancing for...
Abstract To evaluate whether a machine learning classifier can image quality of maximum intensity projection (MIP) images from F18-FDG-PET scans. A total 400 MIP with simulated decreasing acquisition time (120 s, 90 60 30 s and 15 per bed-position) using block sequential regularized expectation maximization (BSREM) beta-value 450 600 were created. was fed 283 rated “sufficient quality” 117 “insufficient quality”. The classification performance the assessed by calculating sensitivity,...
To assess the evolution of administered radiotracer activity for F-18-fluorodeoxyglucose (18F-FDG) PET/CT or PET/MR in pediatric patients (0-16 years) between years 2000 and 2021.
To determine whether magnetic resonance enterography (MRE) performed without intravenous contrast injection is diagnostically noninferior to conventional contrast-enhanced MRE (CE-MRE) in patients with Crohn's disease (CD).This was an Institutional Review Board (IRB)-approved retrospective study. Ninety-six (52 male and 44 female; 47.18 years ± 13.6) a diagnosis of CD underwent at 1.5T including T2 -weighted single-shot turbo-spin-echo, spectral fat presaturation inversion recovery (SPAIR),...