A5024703688- Cardiac Imaging and Diagnostics
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Takotsubo Cardiomyopathy and Associated Phenomena
- Lung Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
- Heart Rate Variability and Autonomic Control
- Cardiac Structural Anomalies and Repair
- Pericarditis and Cardiac Tamponade
- Adipose Tissue and Metabolism
- Cardiac electrophysiology and arrhythmias
- Radiation Therapy and Dosimetry
- Lymphadenopathy Diagnosis and Analysis
- Glioma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Epilepsy research and treatment
- Cancer Immunotherapy and Biomarkers
- Cutaneous Melanoma Detection and Management
- Vascular Malformations Diagnosis and Treatment
- Ultrasound and Hyperthermia Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Thermoregulation and physiological responses
University Hospital of Zurich
2018-2024
University of Zurich
2015-2024
ETH Zurich
2022-2023
University of Pennsylvania
2020-2022
Swiss National Science Foundation
2020
OPO-Stiftung
2020
Novartis Foundation
2020
The natural history, management, and outcome of takotsubo (stress) cardiomyopathy are incompletely understood.The International Takotsubo Registry, a consortium 26 centers in Europe the United States, was established to investigate clinical features, prognostic predictors, cardiomyopathy. Patients were compared with age- sex-matched patients who had an acute coronary syndrome.Of 1750 cardiomyopathy, 89.8% women (mean age, 66.8 years). Emotional triggers not as common physical (27.7% vs....
<h3>Importance</h3> Machine learning algorithms enable the automatic classification of cardiovascular diseases based on raw cardiac ultrasound imaging data. However, utility machine in distinguishing between takotsubo syndrome (TTS) and acute myocardial infarction (AMI) has not been studied. <h3>Objectives</h3> To assess systems for discrimination TTS AMI. <h3>Design, Settings, Participants</h3> This cohort study included clinical data transthoracic echocardiogram results patients with AMI...
Background Sexual dimorphism in cardiac sympathetic outflow has recently gained attention the context of Takotsubo cardiomyopathy. Previous studies suggest that there are sex- and age-dependent differences peripheral autonomic control, however, data on cardiac-specific activation aged women men lacking. Methods results Regional quantitative analysis fluorine-18 (18F)- Dihydroxyphenylalanine (DOPA) uptake was retrospectively performed 133 patients (69 females, mean age 52.4±17.7 years)...
The purpose of this study was to assess whether the performances an automated software for lung nodule detection with computed tomography (CT) are affected by radiation dose and use iterative reconstruction algorithm.A chest phantom (Multipurpose Chest Phantom N1; Kyoto Kagaku Co. Ltd, Kyoto, Japan) 15 pulmonary nodules scanned a total five CT protocol settings up 20-fold reduction. All examinations were reconstructed algorithms ADMIRE 3 5 then analyzed presence fully computer aided system...
Inadequate coronary adenosine response is a potential cause for false negative ischemia testing. Recently, the splenic switch-off (SSO) sign has been identified as promising tool to ascertain efficacy of during vasodilator stress cardiovascular magnetic resonance imaging (CMR). We assessed value SSO predict response, defined an increase in myocardial blood flow (MBF) quantitative perfusion 13 N-ammonia positron emission tomography (PET). prospectively enrolled 64 patients who underwent...
Abstract To evaluate whether a machine learning classifier can image quality of maximum intensity projection (MIP) images from F18-FDG-PET scans. A total 400 MIP with simulated decreasing acquisition time (120 s, 90 60 30 s and 15 per bed-position) using block sequential regularized expectation maximization (BSREM) beta-value 450 600 were created. was fed 283 rated “sufficient quality” 117 “insufficient quality”. The classification performance the assessed by calculating sensitivity,...
To assess the evolution of administered radiotracer activity for F-18-fluorodeoxyglucose (18F-FDG) PET/CT or PET/MR in pediatric patients (0-16 years) between years 2000 and 2021.
High PSMA expression might be correlated with structural characteristics such as growth patterns on histopathology, not recognized by the human eye MRI images. Deep image analysis able to detect differences and therefore predict if a lesion would positive. Therefore, we aimed train neural network based PET/MRI scans increased prostatic uptake axial T2-weighted sequence alone.
Abstract Objectives To introduce an automated computational algorithm that estimates the global noise level across whole imaging volume of PET datasets. Methods [ 18 F]FDG images 38 patients were reconstructed with simulated decreasing acquisition times (15–120 s) resulting in increasing levels, and block sequential regularized expectation maximization beta values 450 600 (Q.Clear 600). One reader performed manual volume-of-interest (VOI) based measurements liver lung parenchyma two readers...
The objective of this study was to assess the feasibility and accuracy a fully automated artificial intelligence (AI) powered coronary artery calcium scoring (CACS) method on ungated CT in oncologic patients undergoing 18F-FDG PET/CT.A total 100 examined between 2007 2015 were retrospectively included. All underwent PET/CT cardiac SPECT myocardial perfusion imaging (MPI) by 99mTc-tetrofosmin within 6 months. CACS manually performed non-contrast ECG-gated scans obtained from SPECT-MPI (i.e.,...
To evaluate the evolution of CT radiation dose in pediatric patients undergoing hybrid 2-[18F]fluoro-2-deoxy-D-glucose (2-[18F]FDG) PET/CT between 2007 and 2021.Data from all aged 0-18 years who underwent 2-[18F]FDG body January May 2021 were reviewed. Demographic imaging parameters collected. A board-certified radiologist reviewed scans measured image noise brain, liver, adductor muscles.294 167 children (72 females (43%); median age: 14 (IQR 10-15) years; BMI: 17.5 15-20.4) kg/m2)...
Abstract Our aim was to identify and quantify high coronary artery calcium (CAC) with deep learning (DL)-powered CAC scoring (CACS) in oncological patients known very (≥ 1000) undergoing 18F-FDG-PET/CT for re-/staging. 100 were enrolled: 50 Agatston scores ≥ 1000 (high CACS group), < (negative control group). All underwent cardiac SPECT myocardial perfusion imaging (MPI) by 99mTc-tetrofosmin within 6 months. manually performed on dedicated non-contrast ECG-gated CT scans obtained from...
This study aimed to evaluate the diagnostic accuracy of Node Reporting and Data System (Node-RADS) in discriminating between normal, reactive, metastatic axillary LNs patients with melanoma who underwent SARS-CoV-2 vaccination. Patients proven a 2-[
Abstract Purpose : To assess the feasibility and accuracy of a fully automated artificial intelligence (AI) powered coronary artery calcium scoring (CACS) method on ungated CT in oncologic patients undergoing 18F-FDG PET/CT. Materials Methods A total 100 examined between 2007 2015 were retrospectively included. All underwent PET/CT cardiac SPECT myocardial perfusion imaging (MPI) by 99mTc-tetrofosmin within 6 months. CACS was manually performed non-contrast ECG-gated scans obtained from...