Hana Chmelařová

ORCID: 0000-0003-2224-0091
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Plant biochemistry and biosynthesis
  • Mass Spectrometry Techniques and Applications
  • Identification and Quantification in Food
  • Antioxidant Activity and Oxidative Stress
  • Metabolomics and Mass Spectrometry Studies
  • Spectroscopy and Chemometric Analyses
  • Analytical Chemistry and Chromatography
  • Nephrotoxicity and Medicinal Plants
  • Isotope Analysis in Ecology
  • Hormonal and reproductive studies
  • Phytochemistry and Biological Activities
  • Fungal Plant Pathogen Control
  • Garlic and Onion Studies

University of Hradec Králové
2024

Charles University
2024

University of Chemistry and Technology, Prague
2015-2022

In this study, an in-depth analysis of the unique set rosehip samples from 71 Rosa genotypes was conducted with aim to identify most suitable ones for applications in food and pharmaceutical industries based on content biologically active compounds. first part our experiments, antioxidant activity determined by 2,2-diphenyl-1-picrylhydrazyl assay highest values were selected follow-up analysis. second major classes compounds rosehips such as carotenoids, tocopherols, flavonoids, triterpenoic...

10.1016/j.jfda.2016.12.019 article EN cc-by-nc-nd Journal of Food and Drug Analysis 2017-02-17

Carrot serves as a source of health-beneficial phytochemicals for human diet whose content is affected by agroecological conditions. The effect conventional, integrated and organic farming on ascorbic acid (AA) α,β-carotene levels new carrot cultivars Cortina F1 Afalon was investigated their metabolomic profiles were measured direct analysis in real time ion coupled with high-resolution mass spectrometer (DART-HRMS). exhibited high AA total carotenes under all conditions tested that...

10.3390/cells10040784 article EN cc-by Cells 2021-04-01

Levothyroxine is a drug with narrow therapeutic index. Changing the formulation composition or switching between pharmaceutical brands can alter bioavailability, which result in major health problems. However, increased adverse reactions have not been fully explained scientifically yet and thorough investigation of formulations needed. In this study, we used non-targeted analytical approach to examine various levothyroxine formulas detail reveal possible chemical changes....

10.1016/j.jpha.2024.100970 article EN cc-by Journal of Pharmaceutical Analysis 2024-03-28

Carrot is the most important root vegetable plant produced worldwide, consumed as a food source rich in bioactive compounds. The purpose was to investigate effect of different farming conditions on content those compounds roots Afalon and Cortina carrot cv. use metabolomic fingerprinting for authentication carrots. Carotenoids ascorbic acid (AA) were detected quantified using LC method. characterization classification samples according production system, variety density performed...

10.3390/agronomy12081770 article EN cc-by Agronomy 2022-07-28
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