A5101453564- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Neurological Disease Mechanisms and Treatments
- Traditional Chinese Medicine Studies
- Blood Pressure and Hypertension Studies
- Nerve injury and regeneration
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Heavy Metal Exposure and Toxicity
- Pregnancy and preeclampsia studies
- Liver Disease Diagnosis and Treatment
- Mercury impact and mitigation studies
- Endoplasmic Reticulum Stress and Disease
- Lipid metabolism and disorders
- Moyamoya disease diagnosis and treatment
- Neurological Complications and Syndromes
- Trauma and Emergency Care Studies
- Nuclear Receptors and Signaling
- Pituitary Gland Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Neurogenesis and neuroplasticity mechanisms
- Neurological Disorders and Treatments
- Bioinformatics and Genomic Networks
- Healthcare Systems and Public Health
- Urinary Tract Infections Management
Chenzhou First People's Hospital
2024
First Affiliated Hospital of Wannan Medical College
2015-2024
Soochow University
2020
First Affiliated Hospital of Soochow University
2020
Wannan Medical College
2015-2020
First Affiliated Hospital of Nanchang University
2019
Nanchang University
2019
Hsin Sheng College of Medical Care and Management
2004
Post-stroke depression (PSD) is the most prevalent psychiatric complication of acute ischemic stroke. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) are indicators inflammation associated with stroke depression. Therefore, purpose present study was to examine relationship between NLR/PLR PSD. Retrospective analysis carried out in 376 patients first-ever First Affiliated Yijishan Hospital Wannan Medical College March 2015 September 2017. Patients were divided into...
Background Polymorphisms of the brain-derived neurotrophic factor (BDNF) have been investigated as candidate genes for post-stroke depression (PSD), and its receptor, tyrosine kinase receptor B (TrkB), has associated with depression. However, no further data yet reported association between PSD polymorphisms in TrkB. This study aims to investigate whether a relationship exists TrkB PSD. Methods A total 312 patients (PSD patients) 472 non-depression patient controls (NPSD were recruited. All...
In this study, we aimed to explore the relationship among miR-22, deep cerebral microbleeds (CMBs), and post-stroke depression (PSD) 1 month after ischemic stroke. We consecutively recruited 257 patients with first-ever recurrent acute infarction performed PSD diagnosis in accordance Diagnostic Statistical Manual IV criteria for depression. Clinical information, assessments of stroke severity, imaging data were recorded on admission. further detected plasma miR-22 using quantitative PCR...
To investigate the association of venous blood neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) levels interleukin-17 (IL-17) IL-6 at 2 weeks after admission with occurrence post-stroke depression (PSD) in patients first-ever acute ischemic stroke.The hospitalized stroke were recruited consecutively from Department Neurology Yijishan Hospital March, 2015 to September, 2017. The demographic baseline clinical data on imaging collected. diagnosis PSD was established line...
To investigate the differential expression of miR-30a-5p in patients with poststroke depression and explore possible mechanism.We obtained target microRNAs through searching PubMed using online software VENNY2.1. We collected baseline demographic, clinical radiographic data from consecutive first-ever acute ischemic stroke on admission our department October, 2018 to March, 2019. From each patient, 5 mL peripheral venous blood was upon admission. Hamilton Depression Scale (HAMD-17) used...
Background: Myasthenia gravis is an autoimmune disease, and 30% of patients with thymoma often have myasthenia gravis. Patients thymoma-associated MG (TAMG) many different clinical presentations compared to non-MG (NMG), yet their gene expression differences remain unclear. Objective: In this study, we analyzed the Differentially Expressed Genes (DEGs) regulatory microRNAs (miRNAs) in TAMG, which will further clarify possible pathogenesis TAMG. Methods: DEGs were calculated using...
The objective of this study is to evaluate the accuracy wrist blood pressure (BP) monitor (TMB-2285-BT) in general population according international standard ISO 81060-2:2018+Amd.1:2020. TMB-2285-BT BP an oscillometric device measuring from wrist. A single cuff for sizes 13.5–21.5 cm was used test device. performed ‘International Standard (ISO 81060-2:2018 + Amd.1:2020) protocol’ using same-arm sequential measurement method. Subjects ( n ≥ 85) fulfilling age, gender, BP, and distribution...
This study aimed to validate the accuracy of test device (TMB-2296-BT) blood pressure (BP) monitor in adults according International Standard Organization (ISO) 81060-2:2018 + Amd.1:2020 universal standard protocol, which is a digital monitor. Three trained observers used same arm sequential method compare SBPs and DBPs measured by with those reference (mercury sphygmomanometer). For cuff ranging from 22 32 cm, there are 88 adults, male-to-female ratio 35 : 53. The mean difference SD between...
Objective To investigate the relationship between lesion sites and post-stroke depression (PSD) in patients with acute ischemic stroke. Methods From January 2015 to June 2016, first-ever stroke admitted Department of Neurology, Wuhu Yijishan Hospital were enrolled prospectively. The demographic baseline clinical data recorded. lesions localized by imaging symptoms within 24 h after admission. divided into PSD group (≥8) non-PSD (<8) according Hamilton Depression Rating Scale score at...
Objective To investigate the association of post-stroke depression (PSD) with tryptophan hydroxylase 2 (TPH2) gene polymorphism and related clinical risk factors PSD. Methods Three hundred seventy-six patients diagnosed as having acute ischemic stroke for first time, admitted to our hospital from March 2015 September 2017, were chosen in study. According Hamilton scale scores Diagnostic statisistical Manual Mental Disorders, fourth edition (DSM-IV), these divided into PSD group...