- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Medical Imaging Techniques and Applications
- Atomic and Subatomic Physics Research
- NMR spectroscopy and applications
- MRI in cancer diagnosis
- Advanced X-ray Imaging Techniques
- Orthopedic Surgery and Rehabilitation
- Advanced Optical Sensing Technologies
- Hepatocellular Carcinoma Treatment and Prognosis
- Osteoarthritis Treatment and Mechanisms
- Advanced NMR Techniques and Applications
- Geological Formations and Processes Exploration
- Liver Disease Diagnosis and Treatment
- Geology and Paleoclimatology Research
- Geological Modeling and Analysis
- Knee injuries and reconstruction techniques
- Shoulder Injury and Treatment
- Laser-Matter Interactions and Applications
- Optical Imaging and Spectroscopy Techniques
- Neurological disorders and treatments
- Muscle activation and electromyography studies
- Photoacoustic and Ultrasonic Imaging
- Electron Spin Resonance Studies
Siemens Healthcare (United States)
2025
Siemens (United States)
2024
Heidelberg University
2018
Resonance Research (United States)
2006-2017
University of Minnesota
2006-2017
University of Minnesota Medical Center
2012
Max Planck Institute for Human Cognitive and Brain Sciences
2007
Chemnitz University of Technology
2007
Ghent University Hospital
2007
Max Planck Society
2002-2005
T1 relaxation time is a tissue-specific parameter that correlates with liver fibrosis, and can be valuable tool for detecting staging of disease. However, affected by histological factors such as fat, so it necessary to study the effects hepatic steatosis when assessing function fibrosis. The purpose this investigate fat separation effect mapping using Dixon watermap Look-Locker inversion recovery (LLIR) in assessment on gadoxetic acid (GA)-enhanced magnetic resonance imaging (MRI). A total...
Heating induced near deep brain stimulation (DBS) lead electrodes during magnetic resonance imaging with a 3 T transceive head coil was measured, modeled, and imaged in three cadaveric porcine heads (mean body weight = 85.47 ± 3.19 kg, mean 5.78 0.32 kg). The effect of the placement extra-cranial portion DBS on heating investigated by looping top, side, back head, placing it parallel to coil's longitudinal axial direction. using 641 s long turbo spin echo sequence whole average specific...
This study evaluates the impact of liver steatosis on discriminative ability for fibrosis and inflammation using a novel Dixon water-only fat-corrected Look-Locker T1 mapping sequence, compared with standard shortened Modified Inversion Recovery (shMOLLI) aim overcoming limitation steatosis-related confounding in mapping.
The objective of this study was to demonstrate the feasibility simultaneous bilateral hip imaging at 7 Tesla. Hip joint MRI becomes clinically critical since recent advances have made arthroscopy an efficacious approach treat a variety early diseases. success these treatments requires reliable and accurate diagnosis intraarticular abnormalities stage. Articular cartilage assessment is especially important guide surgical decisions but difficult achieve with current MR methods. Because gains...
A major allochthon of the Scandinavian Caledonides, Seve belt has traditionally been considered to be derived from rifted margin and continent-ocean transition (COT) Baltica. However, geochronological results obtained its inferred northern equivalent, Kalak Nappe Complex (KNC), have taken indicate an exotic affinity this complex also terranes, interpretation adopted in recent palaeogeographic models. In Kebnekaise Mts., COT is represented by terrane composed amphibolitized dykes gabbro...
Continuous arterial spin labeling (ASL) using a locally induced magnetic field gradient for adiabatic inversion of spins in the common carotid artery human volunteers is demonstrated. The experimental setup consisted helmet resonator imaging, circular RF surface coil labeling, and loops to produce gradient. A spin-echo (SE) echo-planar imaging (EPI) sequence was used imaging. approach independent gradients MR scanner. This technology may be if system does not an appropriate at location...
Abstract Gradient‐echo EPI, blood oxygenation level‐dependent (BOLD) functional MRI (fMRI) using parallel imaging (PI) is demonstrated at 7 Tesla with 16 channels, a fourfold 1D reduction factor ( R ), and maximal aliasing. The resultant activation detection in finger‐tapping fMRI studies was robust, full agreement expected patterns based on prior knowledge, maps generated from field of view (FOV) coverage k ‐space segmented acquisition. In all aspects the acquired PI outperformed ‐space....
Image blurring due to off-resonance and fast T 2* signal decay is a common issue in radial ultrashort echo time MRI sequences. One solution use higher readout bandwidth, but this may be impractical for some techniques like pointwise encoding reduction with acquisition (PETRA), which hybrid method of zero single point imaging techniques. Specifically, PETRA has severe specific absorption rate (SAR) radiofrequency (RF) pulse peak power limitations when using bandwidths human measurements. In...
Spatiotemporally structured noise, such as physiological is a potential source of artifacts in functional magnetic resonance imaging (fMRI) and the main limiting factor for detection small blood oxygen level-dependent (BOLD) signal variations. fMRI was employed to detect low-frequency BOLD fluctuations, which are thought be related spontaneous neuronal activity resting human brain. The sensitivity that is, variations non-BOLD origin, investigated two- (2D) three-dimensional (3D) techniques....
There has recently been increased interest in the use of 7.0-T magnetic resonance imaging for evaluating articular cartilage degeneration and quantifying progression osteoarthritis.The purpose this study was to evaluate cross-sectional area maximum thickness medial compartment intact destabilized canine knees using images compare these results with those obtained from corresponding histologic sections.Controlled laboratory study.Five canines had a surgically created unilateral grade III...
Abstract Ultrashort echo‐time imaging and sweep with Fourier transformation are powerful techniques developed for ultrashort T 2 species. However, it can be challenging to implement them on standard clinical MRI systems due demanding hardware requirements. In this article, the limits of what is possible in terms minimum repetition time 3D radial gradient‐echo sequences, which readily implemented a scanner, investigated. Additionally, new sequence introduced, called COncurrent Dephasing...
Abstract The origin of the stimulus/task‐induced signal changes in spin echo (SE) functional MRI (fMRI) at high magnetic fields is dynamic averaging due to diffusion presence field gradients surrounding deoxyhemoglobin‐containing microvasculature. same mechanism expected be operative stimulated echoes (STE). Compared SE‐fMRI, however, STE‐fMRI has potential for larger weighting and consequently as a result an additional delay, mixing time, T M . In present study, were quantified both primary...
Abstract Purpose To develop a sensitive method for detecting minute transient signal changes that can arise due to variations in the extravascular apparent self‐diffusion coefficient, D , during neuronal activation. Materials and Methods A three‐pulse sequence reads out moderately diffusion‐weighted (DW) primary echo (PRE) heavily DW stimulated (STE) was employed investigate whether small occur response visual stimulus. Contributions caused by subtle differences of transverse relaxation...
The interest in developing quantitative metrics abdominal imaging has grown recent years. In particular, T1 mapping plays a role the characterization of pathologies. However, current abdomen is limited by poor anatomical coverage, long acquisitions related to sufficient sampling recovery curve and times, reduced accuracy secondary respiratory motion. Here we present novel approach for free-breathing abdomen, which leverages undersampling robustness radial MRI combines fast data acquisition...
Comprehensive liver evaluation with T1 mapping requires full abdominal coverage sufficiently high spatial resolution for detection of pathology. Existing methods are only able to achieve partial coverage, primarily limited by the breath hold and time required sample recovery curve (T1RC) accurate estimation. We present a radial Look-Locker framework which utilizes short T1RC sampling combined deep learning based estimation within single 20s period.
Conventional CPMG-based T2 quantitative approaches are often based on prolonged scan and complicated signal modeling, with multiple confounders that affects the accuracy. In this work, we explore an alternative strategy utilizing Single-Shot EPI (SS-EPI) sequence. Phantom in-vivo abdominal imaging results shows despite inferior spatial resolution, SS-EPI could provide descent image quality reliable maps from a faster scan. Common in CPMG approach seems not affecting values SS-EPI. The is...
Abstract Efficient abdominal coverage with T1‐mapping methods currently available in the clinic is limited by breath hold period (BHP) and time needed for T1 recovery. This work develops a framework efficient based on rapid recovery curve (T1RC) sampling, slice‐selective inversion, optimized slice interleaving, convolutional neural network (CNN)‐based estimation. The effect of reducing T1RC sampling was evaluated comparing estimates from ranging 0.63 to 2.0 s reference values obtained =...