A5102951113- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- Mesenchymal stem cell research
- Parkinson's Disease Mechanisms and Treatments
- Radiopharmaceutical Chemistry and Applications
- Gastrointestinal disorders and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Gastrointestinal Tumor Research and Treatment
- Brain Metastases and Treatment
- Bone health and treatments
- Multiple Sclerosis Research Studies
- Anesthesia and Pain Management
- Spinal Hematomas and Complications
- Psoriasis: Treatment and Pathogenesis
- Endometrial and Cervical Cancer Treatments
- Neurogenesis and neuroplasticity mechanisms
- Hepatocellular Carcinoma Treatment and Prognosis
- Nerve injury and regeneration
- Gastrointestinal Bleeding Diagnosis and Treatment
- Viral-associated cancers and disorders
- Genomics, phytochemicals, and oxidative stress
- Cervical and Thoracic Myelopathy
- Ophthalmology and Eye Disorders
- MicroRNA in disease regulation
The First Affiliated Hospital, Sun Yat-sen University
2006-2021
Sun Yat-sen University
2006-2021
Wenzhou Medical University
2015-2020
First Affiliated Hospital of Wenzhou Medical University
2015-2020
Abstract As the most common neurodegenerative disease, Alzheimer's disease (AD) is characterized by memory, perception, and behavioral damage, which may ultimately lead to emotional fluctuation even lethal delirium. Increasing studies indicate that microRNAs (miRNAs) are associated with pathological features of AD. However, role miR‐219‐5p in AD progression still unclear. In this study, functions were analyzed vitro vivo. was notably overexpressed brain tissues patients The overexpression...
Background: Parkinson’s disease (PD) is a neurodegenerative disorder displaying typical neuroinflammation pathology that may result from an imbalance between regulatory T cells (Treg) and helper 17 (Th17) cells. Human adipose tissue-derived mesenchymal stem (Ad-MSCs) exert immunomodulatory effects by inhibiting effector cell responses have been used to treat diverse immune disorders. We aimed investigate the modulating effect of human Ad-MSCs on peripheral blood mononuclear (PBMCs) patients...
Abstract Background Rosai–Dorfman disease (RDD) is a rare, benign, idiopathic non-Langerhans cell histiocytosis. Cases of RDD in the CNS are extremely rare but lethal. thought to represent reactive process. Recent studies proposed subset cases that had clonal nature. However, its clone origin poorly understood. Case presentation We present case with two isolated lesions. These lesions were removed successively after operations. No seizure nor recurrence appears date (2 years follow-up)....
Objective To compare the efficiency of 18F-FDG PET/CT and contrast enhanced ultrasound (CEUS) in detection HCC recurrence after surgery or radiofrequency ablation (RFA).Methods Twenty-seven patients (22 males,5 females; average age:47 years) were included this study,of which 15 underwent 12 RFA therapy.18F-FDG CEUS performed within 2 weeks all to detect recurrence.Final diagnosis was made by pathology clinical follow-up (＞6 months),and sensitivity,specificity accuracy calculated...
Objective To observe the effect of etomidate combined with dezocine used in elderly women painless curettage and safety. Methods All postmenopausal uterine bleeding patients meet to following conditions:American Society Anesthesiologists score I-II,age 50-74 years,weight 41-72kg.60 were randomly divided into two groups,propofol group(group P)and E),30 cases each group;slowly injection dezocine(0.04g/kg)in groups,5min after intravenous propofol group P(0.8-1mg/kg);intravenous...
Objective To investigate the usefulness of 13N-NH3 PET in detecting brain lesions which show hypometabolism on 18F-FDG PET.Methods imaging was performed for a prospective study 18 patients with that showed compared normal tissue scans.Fourteen underwent F-FDG initial diagnosis and 4 detection astrocytoma recurrence (13 males,5 females,age 20-68 (42.4 ± 12.6) years).Ten gliomas,1 metastatic tumor,1 dysembryoplastic neuroepithelial tumor (DNT) 6 non-neoplastic (including 3 cases radiation...
Objective To approach the clinic value of whole body nuclide bone imaging to diagnose earlier period osseous metastasis breast cancer.Methods We made 99mTc-MDP for 208 patients who had diagnosed cancer.Results There were 98 in cancer,the incidence rate was 47.1%.The thoracic part most incident (48.9%),then vertebral (28.5%),pelvis (19.4%),limbs bone(13.3%),skull and other parts(8.2%).Conclusions The is very high cancer patients,and has definite rules features.It worth diagnosing with...
Abstract Parkinson's disease (PD), known as a neurodegenerative disorder, shows typical pathology of neuroinflammation, which might be the result imbalance between regulatory T cells (Treg) and helper 17 (Th17) cells. The present study aimed to investigate modulating effect Ad-MSCs on peripheral blood mononuclear (PBMCs) derived from PD patients. CD4 + were isolated co-cultured with at ratio 4:1 under Th17 or Treg polarizing conditions, respectively, for 4 days. Our results showed that...