A5052198580- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Bacterial Infections and Vaccines
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Orthopedic Infections and Treatments
- Sepsis Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Electrolyte and hormonal disorders
- Venous Thromboembolism Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 detection and testing
- Viral gastroenteritis research and epidemiology
- Cancer-related gene regulation
- Cardiovascular Health and Disease Prevention
- Neuroendocrine Tumor Research Advances
- Alzheimer's disease research and treatments
- Neonatal Respiratory Health Research
- IgG4-Related and Inflammatory Diseases
- Immunotherapy and Immune Responses
- Infant Health and Development
- Neurological diseases and metabolism
- Coronary Interventions and Diagnostics
- Transplantation: Methods and Outcomes
- COVID-19 Clinical Research Studies
Hanyang University
2021-2024
First Affiliated Hospital of Jiangxi Medical College
2022-2024
Jiangxi Provincial People's Hospital
2018-2024
Nanchang University
2020-2024
Xiangya Hospital Central South University
2023-2024
Central South University
2023-2024
Shanghai University of Traditional Chinese Medicine
2023
First Hospital of China Medical University
2022
China Medical University
2022
Beijing Friendship Hospital
2021
Background Early detection and treatment of CIN or early-stage cervical cancer lead to better clinical outcomes compared treating advanced-stage patients. Thus, specific biomarkers for the diagnosis prognosis should be urgently explored. Methods We analyzed tumor based on genes closely related OS in database with GSE63514, GSE7803, GSE9750 TCGA data sets, top 20 core were screened out. Notably, transferrin receptor (TFRC) emerged as a prioritized candidate due its dual role cellular iron...
Objective: Tuberculous meningitis (TBM) is a common form of central nervous system (CNS) tuberculosis (TB). Cranial nerve palsy serious complication TBM. Literature regarding this subject still limited in China. This study evaluated the incidence cranial patients with TBM South China, its association clinical forms TB, and other patient characteristics. Methods: A retrospective chart review diagnosis between January 2004 December 2019 was conducted, demographic characteristics, laboratory...
Background: The discrimination of tuberculous meningitis and bacterial remains difficult at present, even with the introduction advanced diagnostic tools. This study aims to differentiate these two kinds by using rule clinical laboratory features. Methods: A prospective observational was conducted collect parameters patients or meningitis. Logistic regression used define formula for receiver operator characteristic curve established determine best cutoff point formula. Results: Five...
To assess the clinical and safety outcomes of endovascular treatment (EVT) administered more than 24 h after onset symptoms in patients with acute ischemic stroke resulting from anterior circulation large-vessel occlusion or stenosis (AIS-ACLVO/S).We enrolled consecutive AIS-ACLVO/S who received EVT our hospital between January 2019 February 2022 divided them into two groups based on time AIS to EVT: < group >24 group. The successful reperfusion (modified thrombolysis cerebral infarction,...
Copeptin, reflecting vasopressin release, as well the National Early Warning Score (NEWS), severity of critical illness, might qualify for survival prediction in elderly patients with illness. This prospective observational study aims at assessing predictive value copeptin combined NEWS on prognosis ill emergency department (ED).We analyzed serum levels and admission to ED a prospective, single-center, comprising 205 Death within 30 days after was primary end point.The non-survivor group...
Although chimeric antigen receptor T cell (CAR-T) is a promising immunotherapy in hematological malignancies, there remain many obstacles to CAR-T therapy for solid tumors. Identifying appropriate tumor-associated antigens (TAAs) especially critical success. Using bioinformatics approach, we identified common potential TAAs We used the GEO database as training dataset find differentially expressed genes (DEGs) and verified candidates using TCGA database, obtaining seven DEGs (HM13, SDC1,...
Tuberculous meningitis (TBM) is the most serious form of extrapulmonary tuberculosis caused by Mycobacterium tuberculosis, and characterized high morbidity mortality. Unfortunately, it difficult to distinguish TBM from bacterial (BM) based on clinical features alone. The latest diagnostic tests neuroimaging methods are still not available in many developing countries. This study aimed develop a simple algorithm laboratory test results as an early predictor South China.A retrospective was...
Central nervous system (CNS) infection has a high incidence and mortality worldwide. Tuberculous meningitis (TBM) accounts for approximately 5-6% of all extrapulmonary tuberculosis (TB), is considered an extremely lethal form CNS TB, which become important threat to human health. Anemia common symptom its prevalence generally higher in patients with TBM than other healthy individuals. can increase person's susceptibility infectious diseases, including by compromising the immune system....
<title>Abstract</title> Patients with symptomatic intracranial arterial stenosis (sICAS) will likely face perioperative risks stent placement and recurrence medication. Simple balloon angioplasty (SBA), as a less invasive safer alternative to placement, may offer an effective treatment option for sICAS. This study aimed assess the safety of SBA compared medication A retrospective analysis was conducted on sICAS patients admitted Department Neurology, Jiangxi Provincial People's Hospital,...
Background and Objectives: This study aimed to develop an embolic agent with short-term effects using cilastatin as the basic material. Materials Methods: The particle size distribution of 25 mg cilastatin-based agents was evaluated microscopically under three different mixing conditions. A total thirty-six healthy male Sprague Dawley rats were divided into four groups. Each group six injected once tail artery 0.4 mL each (A) Cilastatin + D-Mannitol Mixture, (B) Iohexol, (C) Prepenem, (D)...
To observe the efficacy and safety of self-made covered coronary stent in treatment artery perforation.Covered was prepared by wrapping 3 M film on surface stents. The beagle dogs were divided into control group experimental group. A drug-eluting (DES) implanted applied to block branches dogs. CaIMR value after placement calculated FlashAngio software. effect blocking blood flow observed angiography (CAG). condition optical coherence tomography (OCT), histopathologic examination vessel...
Abstract Background Most human genes have diverse transcript isoforms, which mainly arise from alternative cleavage and polyadenylation (APA) at 3′ ends. N7‐methylguanosine (m 7 G) is also an essential epigenetic modification the 5′ end. However, contribution of these two RNA modifications to development, prognosis, regulation mechanisms, drug sensitivity gastric cancer (GC) unclear. Methods The expression data 2412 patients were extracted 12 cohorts patterns 20 marker systematically...
Abstract The pathogenesis of amyotrophic lateral sclerosis (ALS) remains unclear. recent studies have suggested that the protein abnormalities could play some important roles in ALS because several mutations were found individuals with this disease. However, proteins are currently known to be associated only explain disease a minority cases, thus, further screening is needed identify other ALS‐related proteins. In study, we systematically analyzed and compared brain proteomic alterations...
Abstract Purpose Copeptin, reflecting vasopressin release, as well the National Early Warning Score (NEWS), severity of critical illness, might qualify for survival prediction in elderly patients with acute and illness. This prospective observational study aimed at assessing predictive value copeptin combined NEWS on prognosis Methods We analyzed serum levels admission to emergency department (ED) a prospective, single-center comprising 205 Death within 30 days after ED was primary end...
Abstract Background & Aims: Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition. The aim of the present study was to characterize clinical features and therapeutic response patients with IgG4-RD identify risk factors for relapse. Methods: We collected baseline data eligible analyzed feature by interview review medical records. who received therapy at least 3 months follow-up were used Result: Totally 127 patients, including 92 males 35 females,...