A5006234665- Gastric Cancer Management and Outcomes
- Microbial Inactivation Methods
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Surgical Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Helicobacter pylori-related gastroenterology studies
- Surgical Simulation and Training
- Radiomics and Machine Learning in Medical Imaging
- Anesthesia and Sedative Agents
- Diverticular Disease and Complications
- Metastasis and carcinoma case studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Ultrasound and Cavitation Phenomena
- Toxin Mechanisms and Immunotoxins
- Biliary and Gastrointestinal Fistulas
- Nausea and vomiting management
- Magnetic and Electromagnetic Effects
- Anorectal Disease Treatments and Outcomes
- Tracheal and airway disorders
- Freezing and Crystallization Processes
Korea University
2016-2025
Korea University Medical Center
2020-2022
Seoul National University
2020
National University College
2020
New Generation University College
2020
Korea Research Institute of Standards and Science
2020
Seoul Medical Center
2019
Objectives: The accurate prediction of lymph node metastasis (LNM) and lymphovascular invasion (LVI) is crucial for determining treatment strategies early gastric cancer (EGC). This study aimed to develop validate a deep learning-based clinical decision support system (CDSS) predict LNM including LVI in EGC using real-world data. Methods: A CDSS was developed by integrating endoscopic images, demographic data, biopsy pathology, CT findings from the data 2927 patients with across five...
: Appropriate tissue tension and clear visibility of the dissection area using traction are essential for effective safe endoscopic submucosal (ESD). In this study, we developed a retractable robot-assisted device evaluated its performance in colorectal ESD.
Patient compliance during bowel preparation is important for successful colonoscopy. Bowel with polyethylene glycol (PEG), the most commonly used solution cleansing, involves unpleasant ingestion of a large amount liquid. Sodium picosulfate magnesium citrate (SP-MC) an alternative option better palatability than PEG. Therefore, in this study, we compared efficacy and patient tolerability among following three protocols: 2 L PEG-ascorbic acid (ASc), 1 PEG-ASc plus bisacodyl, SP-MC 340 mL...
Endoscopic submucosal dissection (ESD) is a surgical procedure to remove early neoplastic lesions in the gastrointestinal tract with critical issue of perforation. A fluid cushion, such as normal saline, used cushioning agent prevent perforation; however, its maintenance insufficient for surgery. In this study, we introduce an injectable thermosensitive chitosan solution (CS) β-glycerophosphate (β-GP) injection ESD. The CS/β-GP system optimal β-GP concentration showed drastic viscosity...
Irreversible electroporation (IRE) is a local non-thermal ablative technique currently used to treat solid tumors. Here, we investigated the clinical potency and safety of IRE with an endoscope in upper gastrointestinal tract. Pigs were electroporated recently designed endoscopic catheters esophagus, stomach, duodenum. Two successive strategies introduced optimize electrical energy for digestive First, each organ was upscaled confirm limit inducing improper tissue results, including bleeding...
Nonthermal irreversible electroporation (NTIRE) is emerging as a promising tissue ablation technique. However, maintaining (IRE) electrodes against displacement during strong esophageal spasms remains an obstacle. The present study aimed to evaluate the efficacy and safety of newly designed balloon-type endoscopic IRE catheters. Six pigs were randomly allocated each catheter group, pig was subjected four ablations at alternating voltages 1500 V 2000 V. Esophagogastroscopy performed IRE....
Injectable thermo-sensitive chitosan hydrogels have recently been developed for the use of submucosal fluids in endoscopic dissections (ESD). This study aimed to investigate efficacy and safety during ESD. Submucosal were administered as follows: 0.9% normal saline (NS), 0.4% hyaluronic acid (HA) chitosan/β-glycerophosphate (CS/GP) hydrogel. Each solution was twice into stomach colon a pig, with total 72 ESD procedures performed on 12 pigs. The injected volume procedure-related parameters...
Chitosan, a natural polymer widely used in the biomaterials field, has been proposed as potential submucosal injection solution. The purpose of this study was to compare performance and efficacy aqueous chitosan solution commercialized fluids using three-dimensional sensor evaluate measured parameters.Normal saline (0.9% NaCl), control, Eleview® (Poloxamer 188), Blue EyeTM (0.4% hyaluronic acid), (2.0%) were injected into submucosa porcine stomachs ex vivo. mucosal elevation height, elevated...
INTRODUCTION: Polyethylene glycol with ascorbic acid (PEG/Asc) is a well-established bowel preparation solution guaranteed effectiveness and safety. A new low-volume agent, 1 L-PEG/Asc, has recently been released. This study aimed to compare the cleansing efficacy safety of L-PEG/Asc 2 administered adult outpatients in split-dose manner. METHODS: Outpatients undergoing colonoscopy enrolled single-blinded, single-center, noninferiority conducted between July October 2021 were randomized 1:1...
Iatrogenic stomach perforation is a detrimental, irreversible, and fatal condition. Traditional surgery endoscopic suturing clips devices have been introduced to seal holes prevent sepsis disease progression. However, the development of for perforations remains challenging, with no standard device available. This study investigates superficial layer approximation strengths newly designed ENDOCRAB system gastric wall defects. Thirty porcine stomachs were prepared ex vivo model distributed...
The regulation of apoptosis is the primary goal ablation therapy. Irreversible electroporation (IRE) a promising non-thermal tissue ablation-based therapy that induces by manipulating electrical conditions. This study aimed to investigate IRE-induced gastric in response changes electric field intensity, followed repair process. Among 52 rats used this study, 24 were explore apoptosis, and 28 regeneration. apoptosis-to-necrosis ratio strength was evaluated using terminal deoxynucleotidyl...
<i>Helicobacter pylori</i> (<i>H. pylori</i>) is a bacterium that colonizes the human stomach, leading to various gastrointestinal diseases including gastritis, peptic ulcers, and gastric cancer. There no gold standard test relies entirely on one method in <i>H. diagnosis. We must be aware of pros cons testing methods perform an appropriate according situation. Accurate diagnosis eradication therapy are essential for disease management. Diagnostic include...