A5028841219- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Colorectal Cancer Screening and Detection
- Anesthesia and Sedative Agents
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Anesthesia and Pain Management
- Hepatitis B Virus Studies
- Microbial Inactivation Methods
- Pulsed Power Technology Applications
- Coastal and Marine Dynamics
- Hepatitis C virus research
- Electromagnetic Launch and Propulsion Technology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metastasis and carcinoma case studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastroesophageal reflux and treatments
Korea University
2016-2025
UCLA Medical Center
2023
Harbor–UCLA Medical Center
2023
Weatherford College
2022
Korea University Medical Center
2010-2022
Creative Commons
2022
New Generation University College
2005-2022
Seoul National University
2005-2022
University of the Pacific
2020
Seoul Medical Center
2019
Substance P, acting via the neurokinin 1 receptor (NK1R), plays an important role in mediating a variety of inflammatory processes. However, its acute pancreatitis has not been previously described. We have found that, normal mice, substance P levels pancreas and pancreatic acinar cell expression NK1R are both increased during secretagogue-induced experimental pancreatitis. To evaluate was induced mice that genetically lack by administration 12 hourly injections supramaximally stimulating...
Supramaximal stimulation of the pancreas with CCK analog caerulein causes acute edematous pancreatitis. In this model, active trypsin can be detected in shortly after start supramaximal stimulation. Incubation pancreatic acini vitro a supramaximally stimulating concentration also results rapid activation trypsinogen. current study, we have used techniques subcellular fractionation and both light electron microscopy immunolocalization to identify site trypsinogen subsequent fate during...
A color filter incorporating a subwavelength patterned grating in metal film perforated with square array of circular apertures on quartz substrate was accomplished. Its performance enhanced by applying dielectric overlay to the layer so as match refractive indices media either side it. The device designed utilizing finite-difference time-domain method and implemented adopting electron-beam direct-writing technique. Two different devices were fabricated structural parameters: height 50 nm...
The mechanisms responsible for intrapancreatic digestive enzyme activation as well the relationship between that and cell injury during pancreatitis are not understood. We have employed an in vitro system which freshly prepared pancreatic acini exposed to a supramaximally stimulating concentration of CCK analog caerulein explore these issues. find trypsinogen depends on continued presence Ca 2+ suspending medium it is half-maximal 0.3 mM . Caerulein-induced can be halted by removal from or...
Clevudine is a pyrimidine analogue with potent and sustained antiviral activity against HBV. The present study evaluated the safety efficacy of 30 mg clevudine once daily for 24 weeks assessed durable response after cessation dosing. A total 243 hepatitis B e antigen (HBeAg)-positive chronic patients were randomized (3:1) to receive (n = 182) or placebo 61) weeks. Patients followed further off therapy. Median serum HBV DNA reductions from baseline at week 5.10 0.27 log10 copies/mL in groups,...
Introduction: Because of the increasing use magnetic resonance imaging (MRI), thoracic soft disc herniations are being easily detected in early stages. To avoid a high morbidity rate and other complications that associated with conventional approach, authors have applied percutaneous endoscopic technique.
A completely noninvasive animal model of acute pancreatitis-associated lung injury was used to show that neutrophils, activated by pancreatitis, play a key role in mediating injury. Significant pulmonary complications have been known occur over 50% patients with severe pancreatitis. Recent studies using variety models pancreatitis suggested neutrophil activation may an important However, these models, the interpretation results is complicated because surgical manipulations alone could...
Objectives: The ideal diagnostic criteria of autoimmune pancreatitis (AIP) are still challenging. Therefore, we investigated the clinical features AIP in Korea and assessed use new Korean criteria. Methods: We reviewed 67 patients with enrolled 16 hospitals via a multicenter study. diagnosis was confirmed according to that included pancreatic imaging, laboratory findings, histopathology, response steroid. Results: Mean age 56 years, 73% were men. Obstructive jaundice (52%) most common...
The clinical features and genetics of Rett syndrome (RTT) have been well studied, but examination quality life (QOL) is limited. This study describes the impact severity on QOL among female children adolescents with classic RTT.Cross-sectional longitudinal analyses were conducted data collected from an NIH-sponsored RTT natural history study. More than 200 participants 5 to 18 years age finished their 2-year follow-up at time analysis. Regression models after adjustment for MECP2 mutation...
AIM:To compare the effectiveness of sequential therapy for Helicobacter pylori (H.pylori ) infection with that triple varying durations. METHODS:The 460 patients enrolled in this study had H. -associated gastritis or a gastric duodenal ulcer.After screening, -infected were randomly assigned to receive either conventional 7, 10 14 d, new 10-d therapy.Each 4 treatment groups included 115 patients.The outcomes eradication assessed wk after by urea breath test and histology. RESULTS:The overall...
It remains unclear whether the currently-used normal range for serum alanine aminotransferase (ALT) levels really reflects a healthy liver. The present study was conducted to evaluate of ALT in Korean adult population and determine clinical significance unhealthy levels.We reviewed medical records, including questionnaires results laboratory radiological tests at Health Promotion Center Korea University Anam Hospital between March 2005 February 2007. written questionnaire form, included...
Abstract Background The TeloVac study indicated GV1001 did not improve the survival of advanced pancreatic ductal adenocarcinoma (PDAC). However, cytokine examinations suggested that high serum eotaxin levels may predict responses to GV1001. This Phase III trial assessed efficacy with gemcitabine/capecitabine for eotaxin-high patients untreated PDAC. Methods Patients recruited from 16 hospitals received gemcitabine (1000 mg/m 2 , D 1, 8, and 15)/capecitabine (830 BID 21 days) per month...
Anticancer treatment for acute lymphocytic leukemia is based on drugs such as methotrexate, 6-mercaptopurine, vincristine, and asparaginase. Asparaginase-related pancreatitis known to have an incidence of up 18%, a major cause discontinuation anticancer due onset chronic complications. There were various cases peripancreatic fluid retention caused by in patients. Use lumen-apposing metal stents (LAMS) walled-off necrosis (WON) drainage has recently increased. The electrocautery-enhanced...