A5100351703- Cancer-related molecular mechanisms research
- Pituitary Gland Disorders and Treatments
- Meningioma and schwannoma management
- RNA modifications and cancer
- RNA Research and Splicing
- Cerebral Venous Sinus Thrombosis
- Renal Diseases and Glomerulopathies
- Cytokine Signaling Pathways and Interactions
- MicroRNA in disease regulation
- Carcinogens and Genotoxicity Assessment
- Chronic Kidney Disease and Diabetes
- Epigenetics and DNA Methylation
- Neuroscience of respiration and sleep
- Toxic Organic Pollutants Impact
- Neonatal and fetal brain pathology
- Circular RNAs in diseases
- DNA Repair Mechanisms
- Obstructive Sleep Apnea Research
- Platelet Disorders and Treatments
Capital Medical University
2024-2025
First Affiliated Hospital of Fujian Medical University
2024
Fujian Medical University
2024
Beijing Institute of Neurosurgery
2024
Tianjin Medical University General Hospital
2023
Tianjin Medical University
2019-2022
China Medical University
2022
First Affiliated Hospital of Jiamusi University
2021
Cangzhou Central Hospital
2018
Tulane University
2016
Acute lymphoblastic leukemia (ALL) is characterized by abnormal lymphoblasts accumulation in the bone marrow and blood. Despite great efforts have been made exploring novel therapeutic method, prognosis of children with ALL still unsatisfied. Glucocorticoid (GC) resistance a obstacle for clinical treatment ALL. Therefore, it essential to investigate molecular mechanism underlying GC resistance. According previous reports, long noncoding RNAs (lncRNAs) are involved drug various human cancers....
Gliomas, particularly the advanced grade glioblastomas, have poor 5-year survival rates and worse outcomes. lncRNAs EMT been extensively studied in gliomas but disease progression remains poorly understood. SNHG6 has shown to affect glioma cell proliferation its effect on of cells along with is not known. We screened four lines; H4, A172, U87MG, SW088 grouped them based high vs. low expression. Transfections specific siRNA resulted induction apoptosis expressing A172 U87MG cells. This was...
CCEPR (cervical carcinoma expressed PCNA regulatory lncRNA) has been found to be upregulated and enhance cell proliferation in human cancers. However, the role of osteosarcoma remains discovered. In this study, we expression was elevated tissue specimens lines compared with adjacent normal osteoblast line, respectively. Meanwhile, patients advanced stage or tumor size greater than 8 cm had higher early less equal cm, Survival analysis suggested that high a worse overall survival rate those...
<title>Abstract</title> <bold>Objective: </bold>Preoperative prediction of visual recovery after pituitary adenoma resection surgery remains challenging. This study aimed to investigate the value clinical and radiological features in preoperatively predicting outcomes surgery. <bold>Methods:</bold>Patients undergoing endoscopic transsphenoidal (ETS) for were included this retrospective prospective study. Preoperative MRI, acuity, field, postoperative data collected. Logistic regression...
Objective Preoperative prediction of visual recovery after pituitary adenoma resection surgery remains challenging. This study aimed to investigate the value clinical and radiological features in preoperatively predicting outcomes surgery. Methods Patients undergoing endoscopic transsphenoidal (ETS) for were included this retrospective prospective study. MRI, acuity, field, postoperative data collected. Logistic regression analysis was used assess importance MRI features, a model developed....
Objective Obstructive sleep apnea (OSA) is a sleep-related breathing disorder with high prevalence and associated cognitive impairment. Previous neuroimaging studies have reported abnormal brain functional connectivity (FC) in patients OSA that might contribute to their neurocognitive impairments. However, it unclear whether characteristic pattern of FC changes can serve as biomarker for identifying OSA. Methods A total 21 healthy controls (HCs) were included this study scanned using...
Abstract Background To explore the clinicopathologic features and outcomes of IgAN patients who presented with fibrinoid necrosis (FN) lesions or not effect immunosuppressive (IS) treatment in FN as well. Methods This was a retrospective cohort study 665 diagnosed primary from January 2010 to December 2020 Tianjin Medical University General Hospital having detailed baseline follow-up characteristics. Patients were divided into two groups depending on appearance lesions. recruited Group FN1,...