A5056633426- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Education during COVID-19 pandemic
- Vaccine Coverage and Hesitancy
- Palliative Care and End-of-Life Issues
- Palliative and Oncologic Care
- Systemic Lupus Erythematosus Research
- Healthcare Regulation
- Peripheral Neuropathies and Disorders
- Public Health in Brazil
- Salivary Gland Disorders and Functions
- Patient Dignity and Privacy
- Systemic Sclerosis and Related Diseases
- Rheumatoid Arthritis Research and Therapies
- Healthcare during COVID-19 Pandemic
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- Ocular Surface and Contact Lens
- Heparin-Induced Thrombocytopenia and Thrombosis
- Health, Nursing, Elderly Care
- Dermatological and COVID-19 studies
- Sarcoidosis and Beryllium Toxicity Research
Universidade Federal do Espírito Santo
2019-2025
Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória
2022
Objective: To evaluate the humoral response to and impact of SARS-CoV-2 vaccination in patients with systemic lupus erythematosus a multicenter cohort design. Methods: Data for this analysis were obtained from Study Safety, Effectiveness Duration Immunity after Vaccination against Patients Immune-Mediated Inflammatory Diseases (SAFER), prospective, multicenter, phase IV, real-world study conducted across different regions Brazil June/2021 March/2024. aged >18 years (SLE) who received any...
The present study aimed at investigating whether the hydroxychloroquine (HCQ) treatment would impact neutralizing antibody production, viremia levels and kinetics of serum soluble mediators upon planned 17DD-Yellow Fever (YF) primovaccination (Bio-Manguinhos-FIOCRUZ) primary Sjögren's syndrome (pSS). A total 34 pSS patients 23 healthy controls (HC) were enrolled. group was further categorized according to use HCQ (HCQ Non-HCQ). YF-plaque reduction neutralization test (PRNT ≥1:50), YF...
Abstract Objective: To perform a situational diagnosis of population hospitalized with chronic non-communicable diseases (NCD) who are potentially entitled to palliative care in university hospital. Method: A quantitative study document analysis was carried out. The analyzes were categorized by the following variables: baseline diagnosis, age, sex, readmission and PPS (Palliative Performance Scale) score. Results: Over two months research among 631 patients, 198 patients identified; 113...
Introduction: coronavirus disease 2019 (COVID-19) is a complex multisystem disorder. It not yet well known whether symptoms in the acute phase correlate with duration of immune response and persistence chronic symptoms.
 Objective: this study aimed to assess monitor clinical COVID-19 them production neutralizing antibodies.
 Methods: cohort 69 health workers at University Hospital Federal Espírito Santo (HUCAM-UFES/EBSERH) diagnosed SARS-CoV-2 infection confirmed via RT-PCR...
Dentre as vacinas contra a COVID-19 aprovadas pela ANVISA e incorporadas ao Programa Nacional de Imunização (PNI) destacam-se vacina vírus inativado CoronaVac (Sinovac/Butantan), ChAdOx1 (AstraZeneca/Fiocruz) em plataforma com vetor viral. Diferentes mecanismos ação resultam diferentes reações adversas imunizante. O objetivo deste trabalho é avaliar frequência gravidade dos eventos adversos relacionados às (VAC) AstraZeneca (AZV) uma coorte trabalhadores da saúde. Estudo longitudinal...
Objective: To evaluate the humoral response to and effectiveness of SARS-CoV-2 vaccination in patients with systemic lupus erythematosus a multicenter cohort design. Methods: Data for this analysis were obtained from Study Safety, Effectiveness Duration Immunity after Vaccination against Patients Immune-Mediated Inflammatory Diseases (SAFER), prospective, multicenter, phase IV, real-world study conducted across different regions Brazil. aged >18 years (SLE) who received any one...
A pandemia de COVID-19 iniciou a corrida do desenvolvimento vacinas globalmente. Os trabalhadores da saúde foram o primeiro grupo receber imunizantes, e no Brasil os mais utilizados CoronaVac AstraZeneca. O presente estudo teve como objetivo avaliar imunogenicidade duração resposta às Coronavac Astrazeneca. Este coorte foi realizado Hospital Universitário Universidade Federal Espírito Santo (HUCAM-UFES/EBSERH). No total, 476 recrutados, 261 215 completamente imunizados com duas doses vacina...
Previously, we presented the effectiveness of ChAdOx1 nCoV-19 half-dose (HD) immunization for preventing new COVID-19 cases. Here, evaluated administration an HD in primary protocol (up to two doses) reducing moderate and severe cases, hospitalizations, deaths when compared full doses (FD) after a long-term follow-up.We data from 29,469 participants between January 2021 November 2022 who received or FD vaccine crossed this information with their medical records identify those developed All...
A vacina de vírus inativado CoronaVac (Sinovac/Butantan), e a ChAdOx1 (AstraZeneca/Fiocruz) em plataforma vetor viral foram os principais imunizantes incorporados ao Programa Nacional Imunização (PNI) no Brasil para prevenção da hospitalização infecção pelo SARS-CoV-2. Além ocorrer após as duas primeiras doses, presença eventos adversos ocorre também terceira dose anti-COVID-19, especialmente nos esquemas híbridos. O objetivo deste trabalho é descrever frequência gravidade dos relacionados à...
A escassez de insumos tem limitado o avanço da vacinação contra a Covid-19, no mundo. com meia dose ChAdOx1 nCOv-19 foi comparada à padrão Estudo Viana. O objetivo deste estudo avaliar e monitorar os eventos adversos comparar padrão. Ensaio clínico fase III que testou nCoV-19 (AZD1222) em adultos 18 49 anos cidade Viana - Espírito Santo. Os foram avaliados por meio registros sistema e-SUS notifica, busca ativa estudos casos pós-vacina (EAVP) interesse especial (EAIE), telefone celular 0800...
Ainda não é completamente conhecido como a gravidade do quadro clínico da doença por coronavírus 2019 (COVID-19) se correlaciona com resposta imune. O objetivo deste estudo foi monitorar os sintomas, produção de anticorpos e função pulmonar em uma coorte profissionais saúde seis meses. Estudo longitudinal observacional 69 trabalhadores Hospital Universitário Universidade Federal Espírito Santo (HUCAM-UFES/EBSERH) diagnóstico infecção SARS-CoV-2 confirmado RT-PCR. Análises sorologia IgG IgM,...
CONCLUSIONAlmost half SLE patients presented with flu-like symptoms, but majority had mild despite being an immunosuppressed population comorbidities.Minority promptly access to diagnostic tests for COVID-19, the history exposure suspicious cases, these facts reflect difficulty in certain Brazil locations, which may have contributed spread of disease.Among those tested, was negative, be due non-infection, low sensitivity and possible errors sample collection time window.In addition,...
This study aimed to evaluate IgG and IgM levels in COVID-19 recurrence.The serum antibody clinical data from 73 healthcare workers with SARS-CoV-2 divided into seroconverted (n=51) non-seroconverted (n=22) groups were assessed. The presence of specific anti-nucleocapsid (anti-N) for was evaluated. antibodies the spike receptor-binding domain used confirm non-seroconversion all negative anti-N.Four recurrent cases displayed mild symptoms until recurrence symptoms.Undetectable may be...