A5057893609- Chromosomal and Genetic Variations
- Epigenetics and DNA Methylation
- Genomics and Phylogenetic Studies
Universitat Pompeu Fabra
2022-2023
Institut de Biologia Evolutiva
2022-2023
Abstract Recent advances in long-read sequencing technologies have allowed the generation and curation of more complete genome assemblies, enabling analysis traditionally neglected chromosomes, such as human Y chromosome (chrY). Native DNA was sequenced on a MinION Oxford Nanopore Technologies device to generate assemblies for seven major chrY haplogroups. We analyzed compared enrichment data obtained using two different selective approaches: adaptive sampling flow cytometry sorting. show...
Abstract Recent advances in long-read sequencing technologies have allowed the generation and curation of more complete genome assemblies, enabling analysis traditionally neglected chromosomes, such as human Y chromosome (chrY). Native DNA was sequenced on a MinION Oxford Nanopore Technologies device to generate assemblies for 7 major chrY haplogroups. We analyzed compared enrichment data obtained using two different selective approaches: adaptive sampling flow cytometry sorting. show that...