- Genetics and Neurodevelopmental Disorders
- Ubiquitin and proteasome pathways
- Epigenetics and DNA Methylation
- 14-3-3 protein interactions
- Wnt/β-catenin signaling in development and cancer
- Bioinformatics and Genomic Networks
- Computational Drug Discovery Methods
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
Tianjin Medical University Cancer Institute and Hospital
2024
Fujian Medical University
2024
North Sichuan Medical University
2022
Abstract Background Studies have shown that long noncoding RNAs and N6-methyladenosine play important roles in gastric cancer. The purpose of this study was to determine the correlation prognostic value m6A-related lncRNAs immune infiltration Methods We downloaded clinically related information RNA-Seq transcriptome data cancer patients from TCGA database. Univariate Cox regression analysis Pearson were used screen out lncRNAs. Consensus cluster divide sample into two clusters, LASSO...
<title>Abstract</title> Breast cancer is one of the most prevalent and diverse malignancies, and, with global cases increasing, need for biomarkers to inform individual sensitivity chemotherapeutics has never been greater. Our retrospective clinical analysis predicted that expression fragile site-associated tumor suppressor (FATS) gene was associated breast neoadjuvant chemotherapy paclitaxel. <italic>In vitro</italic> experiments subsequently demonstrated FATS significantly increased...
Abstract Breast cancer is one of the most prevalent and diverse malignancies, and, with global cases increasing, need for biomarkers to inform individual sensitivity chemotherapeutics has never been greater. Our retrospective clinical analysis predicted that expression fragile site-associated tumor suppressor (FATS) gene was associated breast neoadjuvant chemotherapy paclitaxel. In vitro experiments subsequently demonstrated FATS significantly increased inhibitory effects paclitaxel on...