A5055250649- Diet and metabolism studies
- Gut microbiota and health
- Stress Responses and Cortisol
- Pancreatic function and diabetes
- Diet, Metabolism, and Disease
- Tryptophan and brain disorders
- Diabetes Treatment and Management
- Medicinal Plants and Neuroprotection
- Chronic Kidney Disease and Diabetes
- Neurological Disease Mechanisms and Treatments
- Salivary Gland Disorders and Functions
- Microbial Metabolites in Food Biotechnology
- Drug-Induced Hepatotoxicity and Protection
- Vitamin C and Antioxidants Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Biochemical effects in animals
- Neuroendocrine regulation and behavior
- Pancreatitis Pathology and Treatment
- Digestive system and related health
- Diabetes and associated disorders
- Complementary and Alternative Medicine Studies
- Gastrointestinal motility and disorders
- Pharmacological Effects of Natural Compounds
- Oral microbiology and periodontitis research
- Adipose Tissue and Metabolism
Mae Fah Luang University
2016-2023
Chiang Mai University
2016-2018
Siriraj Hospital
2017
Mahidol University
2017
Chronic high-fat diet (HFD) consumption caused not only obese-insulin resistance, but also cognitive decline and microglial hyperactivity. Modified gut microbiota by prebiotics probiotics improved resistance. However, the effects of prebiotics, probiotics, synbiotics on cognition activity in an resistant condition have yet been investigated. We aimed to evaluate effect prebiotic (Xyloolidosaccharide), probiotic (Lactobacillus paracasei HII01), or male rats induced a HFD.Male Wistar were fed...
Aim To evaluate the renoprotective roles of dapagliflozin in prediabetic rats order to elucidate effects this sodium‐glucose co‐transporter‐2 (SGLT2) inhibitor on renal complications associated with metabolic dysfunction diet‐induced obesity. Methods Obesity was induced by feeding a high‐fat diet (HFD) male Wistar for 16 weeks. HFD‐fed were treated (1 mg/kg/d) or metformin (30 oral gavage 4 weeks after insulin resistance had been established. The characteristics and function lipid...
Gentamicin is a commonly used aminoglycoside antibiotic. However, its therapeutic use limited by nephrotoxicity. The mechanisms of gentamicin-induced nephrotoxicity are principally from renal inflammation and oxidative stress. Since atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, exerts lipid-lowering effects, antioxidant, anti-inflammatory as well anti-apoptotic this study aimed to investigate the protective effects atorvastatin against Male Sprague Dawley rats...
The relationship between gut dysbiosis and obesity is currently acknowledged to be a health topic which causes low-grade systemic inflammation insulin resistance may damage the kidney. Organic anion transporter 3 (Oat3) has been shown as responsible for renal handling of microbiota products are involved in progression metabolic disorder. present study investigated effect probiotic supplementation on kidney function, Oat3 inflammation, endoplasmic reticulum (ER) stress, apoptosis obese,...
Obesity is health issue worldwide, which can lead to kidney dysfunction. Prebiotics are non-digestible foods that have beneficial effects on health. This study aimed investigate the of xylooligosaccharide (XOS) renal function, organic anion transporter 3 (Oat3) and mechanisms involved. High-fat diet was provided for 12 weeks in male Wistar rats. After that, rats were divided into normal (ND); treated with XOS (NDX); high-fat (HF) (HFX). given daily at a dose 1000 mg weeks. At week 24, HF...
The aim of this study was to evaluate whether an aqueous extract Azadirachta indica A. Juss. (A. indica) flower had anxiolytic and antidepressant-like effects in the stressed rats. Male Wistar rats were randomly allocated one two experimental groups: control or stress. stress groups received restraint for 3 h. administered a vehicle, diazepam, fluoxetine, at doses 250, 500, 1000 mg/kg BW 30 days. elevated plus-maze test (EPMT), forced swimming (FST), open field (OFT) used assess behaviors....
Neuroprotective effects of Tacca chantrieri Andre against lipopolysaccharide-induced cognitive impairment and neuroinflammation
Chronic exposure of pancreatic β-cells to high glucose levels results in β-cell dysfunction and death. These effects can be protected by estrogen. The local renin-angiotensin system (RAS) has been shown as a novel pathological pathway high-glucose-induced cell effect estrogen on RAS is still unknown. This study examines whether protects against death caused glucotoxicity via decrease the pathway. When INS-1 cells were cultured medium, was significantly higher than when basal medium;...
Our previous studies demonstrated that chronic high-fat diet (HFD) consumption caused not only obese-insulin resistance, but also increased brain oxidative stress, mitochondrial dysfunction, synaptic dysplasticity, and the cognitive decline. Recent showed either prebiotics or probiotics therapy reduced gut inflammation improved glycemic control in obese mice. However, effects of prebiotics, synbiotics on function, hippocampal plasticity function resistant model have been investigated. The...
Azadirachta indica A. Juss flower extract attenuates memory deficit - induced by restraint stress in male rats