A5016761656- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Immunodeficiency and Autoimmune Disorders
- Sepsis Diagnosis and Treatment
- Privacy-Preserving Technologies in Data
- RNA modifications and cancer
- Blood disorders and treatments
- Reproductive Biology and Fertility
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Cytomegalovirus and herpesvirus research
- Stochastic Gradient Optimization Techniques
- Vitamin C and Antioxidants Research
- Seismic Performance and Analysis
- Blood groups and transfusion
- Electrolyte and hormonal disorders
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Human Mobility and Location-Based Analysis
- Coffee research and impacts
- Liver Diseases and Immunity
- S100 Proteins and Annexins
- Intensive Care Unit Cognitive Disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Vitamin D Research Studies
University of Naples Federico II
2006-2024
Ceinge Biotecnologie Avanzate (Italy)
2022-2024
Federico II University Hospital
2022
Objective A beneficial role of antioxidants in hepatopathic obese individuals has hitherto been inferred only from uncontrolled pilot studies. The authors compared the effect vitamin E and weight loss on transaminase values ultrasonographic bright liver a controlled group children with obesity-related dysfunction. Methods Twenty-eight hypertransaminasemia were randomly allocated to two single-blind groups: 1 (n = 14) treated low-calorie diet associated oral placebo for 5 months, 2 (400 mg/d...
A chimeric protein, in which a cationic antimicrobial peptide was fused to the adhesive self-assembling moiety of fungal class I hydrophobin, produced and used easily functionalize gold nanoparticles (f-AuNPs). f-AuNPs are able bind Escherichia coli Staphylococcus epidermidis bacteria, tested as model organisms. reverse colorimetric assay then set up based on induced aggregation free f-AuNPs. This leads changes optical properties solution, visible even by naked eyes. approach allows...
Coffee consumption is inversely associated with the risk of non-alcoholic fatty liver disease (NAFLD). A gap in literature still exists concerning intestinal mechanisms that are involved protective effect coffee towards NAFLD. In this study, twenty-four C57BL/6J mice were divided into three groups each receiving a standard diet, high-fat diet (HFD) or an HFD plus decaffeinated (HFD+COFFEE) for 12 weeks. supplementation reduced HFD-induced macrovesicular steatosis (P < 0·01) and serum...
The optimal strategy for identification of hemodynamically stable patients with acute pulmonary embolism (PE) at risk death and clinical deterioration remains undefined.
<h3>Objective</h3> Achieving glycaemic control is essential to avoid disease progression and diabetes-related complications. Non-adherence discontinuity in diabetic therapy are major barriers optimal control. The aim of this study was evaluate adherence, persistence switching over 1 year real-life conditions patients with type 2 diabetes within an Italian region. <h3>Methods</h3> A retrospective, observational, non-interventional conducted, analysing treated Anatomical Therapeutic Chemical...
The aim of this study was to evaluate the impact pre- mature progesterone rise on day human chorionic gonadotropin (hCG) administration outcome in vitro fertilization (IVF) frozen embryo transfer (FET) cycles using cleavage-stage embryos.This a retrospective, cohort 131 ovarian stimulation followed by transfers. first group consisted women undergoing FET due premature luteinization during controlled (n = 56, P ≥1.2 ng/ml). controls were represented not complicated high levels at induction...
Morbidity and mortality of primary secondary antibody deficiencies (AD) are frequently associated with diagnostic delays. These could be avoided by a combination factors including widespread effective development in screening tests.Calculated globulin (CG), derived from the difference between serum total protein albumin levels, reflects immunoglobulin levels has shown to have predictive value early diagnosis deficiencies. This study investigated possibility use low CG detect deficiency an...
Inflammation plays a crucial role in worsening coronavirus disease (COVID-19). Calprotectin is pro-inflammatory molecule produced by monocytes and neutrophilic granulocytes. The aim of the study was to evaluate both prognostic circulating calprotectin levels neutrophil count toward fatal outcome COVID-19 patients. We retrospectively collected analyzed data on 195 adult patients, 156 hospitalized infectious unit 39 intensive care (ICU). counts measured at first hospitalization day were higher...
Abstract Background Calcium (Ca 2+ ) and vitamin D (VitD) play an important role in child health. We evaluated the daily intake of Ca VitD healthy children. Moreover, we demonstrate efficacy supplementation. Methods Daily 2 + was consecutive children through a validated questionnaire. Subjects with <70% dietary reference intakes (DRIs) were invited to participate prospective randomized trial groups nutritional intervention: Group 1, counseling aiming optimize plus administration...
Increased concentrations of B-type natriuretic peptide (BNP), N-terminal pro-B-type (NT-proBNP) and high-sensitivity troponin I (HsTnI) in COVID-19 patients have already been reported. The aim this study is to evaluate which these common markers cardiac disease the most useful predictor fatal outcome patients. One hundred seventy-four affected with were recruited, clinical history collected at admission infectious unit or intensive care unit. NT-proBNP, BNP HsTnI values higher in-hospital...
Background and objectives: ischemic stroke (IS) is among the most frequent causes of death worldwide; thus, it paramount relevance to know predisposing factors that may help identify treat high-risk subjects. Materials Methods:we tested nine variants in genes involved thrombotic pathway 282 patients experienced IS 87 had transient attacks (TIA) comparison 430 subjects from general population (GP) same geographic area (southern Italy). We included cases young child evaluate eventual...
This paper investigates the symbiosis of Federated Learning (FL) and High-Performance Computing (HPC) architectures, unraveling challenges introduced by intricate interplay heterogeneity non-Independently Identically Distributed (non-lID) data. By leveraging Flower framework, our research delves into nuanced implications FL in diverse HPC environments. We provide a comprehensive exploration within contemporary spanning node organizations, memory hierarchies, special-ized accelerators,...
In the realm of edge cloud computing (ECC), Federated Learning (FL) revolutionizes decentralization machine learning (ML) models by enabling their training across multiple devices. this way, FL preserves privacy and minimizes need for centralized data processing near source. From a communication standpoint, only model weights are exchanged between By avoiding to send location processing, reduces energy required transfer supports more efficient use resources at edge. is particularly...
Annexin VII was present in reticulocytes but then lost as the cells matured. A different pattern found band 3‐deficient samples: annexin fact both mature and immature red cell membranes. Cytoskeletal anomalies may influence turn‐over of during erythrocyte maturation.
Abstract Aims Testosterone deficiency (TD) is associated with increased morbidity and mortality in heart failure reduced ejection fraction (HFrEF). However, data women are scanty. The aim of this study was to investigate the prognostic impact TD on HFrEF. Methods Among 480 patients prospectively enrolled T.O.S.CA. (Terapia Ormonale Scompenso CArdiaco) registry, a prospective, multicentre, nationwide, observational study, 94 were included current analysis. defined as serum testosterone levels...
ABSTRACT Objective A beneficial role of antioxidants in hepatopathic obese individuals has hitherto been inferred only from uncontrolled pilot studies. The authors compared the effect vitamin E and weight loss on transaminase values ultrasonographic bright liver a controlled group children with obesity‐related dysfunction. Methods Twenty‐eight hypertransaminasemia were randomly allocated to two single‐blind groups: 1 (n = 14) treated low‐calorie diet associated oral placebo for 5 months, 2...
The "Intelligent BIOsensors based on CHImeric Proteins" (BIOCHIP) project aims to design Machine Learning (ML) models detect the presence of mercury (Hg <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2+</sup> ) in water. Indeed is dangerous for humans, even at low levels. If breathed, it can be lethal, and if absorbed through skin, toxic. Nowadays, such detection performed by using expensive machines instruments also requiring specialized...
Federated Learning (FL) diverges from traditional Machine (ML) models decentralizing data utilization, addressing privacy concerns. This approach involves iterative model updates, where individual devices compute gradients based on local data, share updates with a central server, and receive an improved global model. High-Performance Computing (HPC) systems enhance FL efficiency by leveraging parallel processing. In this study, we aim to explore using four aggregation methods three datasets...