- Silk-based biomaterials and applications
- Wound Healing and Treatments
- Biological Research and Disease Studies
- Venomous Animal Envenomation and Studies
- Virology and Viral Diseases
- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Viral Infections and Immunology Research
- Healthcare and Venom Research
- Plant-Derived Bioactive Compounds
- Natural Compounds in Disease Treatment
- Marine Bivalve and Aquaculture Studies
- Fatty Acid Research and Health
- Angiogenesis and VEGF in Cancer
- Protein Hydrolysis and Bioactive Peptides
- Aquaculture Nutrition and Growth
- Planarian Biology and Electrostimulation
- Food Chemistry and Fat Analysis
- Phytochemistry Medicinal Plant Applications
Instituto Adolfo Lutz
2024
Instituto Butantan
2007-2018
Institute of Parasitology
2007
Abstract Previously, mucus of some molluscs has been studied as a potential source new natural compounds capable inducing cell proliferation and remodelling tissue. Here, the focus study is possible use released by Phyllocaulis boraceiensis – compound enhancing collagen synthesis in dermal fibroblasts human endothelial cultures. Fibroblasts treated with P. at concentrations below 0.012 μg/μl developed high rates proliferation, evaluated using MTT assay; proliferative effect was...
Phyllocaulis boraceiensis mucus has been studied as a potential source of new natural compounds that are capable inducing proliferation and remodeling tissue. The aim this study was to evaluate the clinical aspects healing in wounded mouse skin, which treated with an ointment composed mucus, released by P boraceiensis.Mice were submitted 1-cm dorsal excision. control group (T1) papain; T2 papain associated 0.18 μg/μL mucus; T3 0.012 mucus.Accelerated observed after 3 days group, presenting...
Phyllocaulis boraceiensis mucus is known to be a compound capable of inducing cell proliferation and enhancing the wound healing process. The process angiogenesis chain mechanisms responsible for formation new vessels, which are involved in proliferation, factors that will act Our aim was demonstrate enhanced cultures endothelial cells fibroblasts treated with P. mucus. Experiments were carried out 10(5) cells·mL(-1) concentrations have significant effects assays, i.e. 0.012 μg·μL(-1) 0.18 ,...
Natterins, isolated toxins from Thalassophryne nattereri (niquim) fish venom, is a family of 5 which present homology amongst themselves and molecular mass around 30-45 kDa.The group majority Natterin 1, 2 3 was used for the evaluation inflammatory response in mice.The kinetic leukocyte recruitment, cytokine chemokine levels matrix metalloproteinases 9 activity after administration Natterins footpad Swiss mice determined.After 6, 24 48 hours or 7, 14 21 days animals injected with 10...