A5080199119- Hearing Loss and Rehabilitation
- Noise Effects and Management
- Hearing, Cochlea, Tinnitus, Genetics
- Speech and Audio Processing
- Neuroscience and Music Perception
- Vestibular and auditory disorders
- Hearing Impairment and Communication
- Phonetics and Phonology Research
- Multisensory perception and integration
- Neural dynamics and brain function
- Delphi Technique in Research
- Structural Health Monitoring Techniques
- Neural and Behavioral Psychology Studies
- Ear Surgery and Otitis Media
- Olfactory and Sensory Function Studies
- RNA regulation and disease
- Advanced Chemical Sensor Technologies
- Neurobiology of Language and Bilingualism
- Infant Health and Development
- Neuroendocrine regulation and behavior
- EEG and Brain-Computer Interfaces
- Acoustic Wave Phenomena Research
- Biochemical Analysis and Sensing Techniques
- Child and Adolescent Psychosocial and Emotional Development
- Nasal Surgery and Airway Studies
Medical University of South Carolina
2016-2025
Collaborative Research Group
2025
Google (United States)
1981-2023
National Institute on Deafness and Other Communication Disorders
2013-2023
Textron Systems (United Kingdom)
2023
Cochlear (Australia)
2020
University of South Carolina
2017
Kansas City Kansas Community College
2013
Northwestern University
2013
University of South Florida
2013
Using an adaptive strategy, the effects of mild sensorineural hearing loss and adult listeners’ chronological age on speech recognition in babble were evaluated. The signal-to-babble ratio required to achieve 50% was measured for three materials presented at soft loud conversational levels. Four groups subjects tested: (1) normal-hearing listeners <44 years age, (2) old with excellent quiet, (3) >65 normal hearing, (4) performance quiet. Groups 1 3, 2 4 matched basis pure-tone...
Abstract The anterior insula has been hypothesized to provide a link between attention‐related problem solving and salience systems during the coordination evaluation of task performance. Here, we test hypothesis that insula/medial frontal operculum (aI/fO) provides linkage across supporting demands attention by examining patterns functional connectivity word recognition spatial imaging tasks. A shared set regions (right aI/fO, right dorsolateral prefrontal cortex, bilateral cingulate) were...
Importance Noise exposure is a major modifiable risk factor for hearing loss, yet it not known whether affects the rate of decline in aging. Objective To determine association noise history with pure-tone threshold change per year. Design, Setting, and Participants This longitudinal cohort study was conducted ongoing community-based Medical University South Carolina Longitudinal Cohort Study Age-Related Hearing Loss (1988 to present sample based Charleston, Carolina, surrounding area)....
In Brief Objective: Pure-tone thresholds for conventional and extended high frequencies were analyzed 188 older adult human subjects (91 females, 97 males). The objectives to study longitudinal changes in as well the effects of initial threshold levels, age, gender, noise history on these changes. Design: At time entry into study, subjects' ages ranged from 60 81 years, with a mean age 68 years. Subjects had between 2 21 visits (mean = 9.81 visits) over period 3 11.5 years 6.40 years)....
Abstract Listening to speech in noise can be exhausting, especially for older adults with impaired hearing. Pupil dilation is thought track the difficulty associated listening at various intelligibility levels young and middle‐aged adults. This study examined changes pupil response acoustic lexical manipulations of hearing loss. Participants identified words two signal‐to‐noise ratios ( SNR s) among options that could include a similar‐sounding competitor. Growth Curve Analyses revealed was...
Recognizing speech in difficult listening conditions requires considerable focus of attention that is often demonstrated by elevated activity putative systems, including the cingulo-opercular network. We tested prediction provides word-recognition benefit on a subsequent trial. Eighteen healthy, normal-hearing adults (10 females; aged 20–38 years) performed word recognition (120 trials) multi-talker babble at +3 and +10 dB signal-to-noise ratios during sparse sampling functional magnetic...
Although many individuals with hearing loss could benefit from intervention aids, do not seek or delay seeking timely treatment after the onset of loss. There is limited data-based evidence estimating in adoption aids anecdotal estimates ranging 5 to 20 years. The present longitudinal study first assess time aid candidacy a 28-year ongoing prospective cohort older adults, additional goal determining factors influencing delays adoption, and self-reported successful use aids.As part...
Speech recognition in noise can be challenging for older adults and elicits elevated activity throughout a cingulo-opercular network that is hypothesized to monitor modify behaviors optimize performance. A word experiment was used test the hypothesis engagement provides performance benefit adults. Healthy ( N = 31; 50–81 years of age; mean pure tone thresholds <32 dB HL from 0.25 8 kHz, best ear; species: human) performed multitalker babble at 2 signal-to-noise ratios (SNR +3 or +10 dB)...
Purpose Valid, reliable, and efficient patient-reported outcome measures are needed to quantify quality of life (QOL) outcomes after cochlear implantation supplement information obtained from performance-based outcomes. We previously developed the Cochlear Implant Quality Life (CIQOL) item bank serve as source items for subsequent instruments. This study reports development psychometric properties 2 these new instruments, CIQOL-35 Profile CIQOL-10 Global. Method implant (CI) users referred...
BACKGROUNDCisplatin is widely used to treat adult and pediatric cancers. It the most ototoxic drug in clinical use, resulting permanent hearing loss approximately 50% of treated patients. There a major need for therapies that prevent cisplatin-induced loss. Studies mice suggest concurrent use statins reduces loss.METHODSWe examined thresholds from 277 adults with cisplatin head neck cancer. Pretreatment posttreatment audiograms were collected within 90 days initiation completion therapy. The...
Age-related hearing loss, or presbyacusis, is a common degenerative disorder affecting communication and quality of life for millions older adults. Multiple pathophysiologic manifestations, along with many cellular molecular alterations, have been linked to presbyacusis; however, the initial events causal factors not clearly established. Comparisons transcriptome in lateral wall (LW) other cochlear regions mouse model (of both sexes) “normal” age-related loss revealed that early...
Current research lacks detail on sex and race differences in the prevalence of hearing loss, including degree loss across adult lifespan whether associated risk factors for may vary groups. To evaluate sex-specific race-specific This study was conducted ongoing community-based Medical University South Carolina Longitudinal Cohort Study Age-Related Hearing Loss Charleston, (1988 to present, with sample based Carolina, surrounding area). Data were analyzed between May October 2024. Demographic...
To assess age-related differences in benefit from masker modulation, younger and older adults with normal hearing but not identical audiograms listened to nonsense syllables each of two maskers: (1) a steady-state noise shaped match the long-term spectrum speech, (2) this same modulated by 10-Hz square wave, resulting an interrupted noise. An additional low-level broadband was always present which produce equivalent masked thresholds for all subjects. This minimized speech audibility due...
Word recognition in sentences with and without context was measured young aged subjects normal but not identical audiograms. Benefit derived from by older adults has been obscured, part, the confounding effect of even mildly elevated thresholds, especially as listening conditions vary difficulty. This problem addressed here precisely controlling signal-to-noise ratio across accounting for individual differences ratio. Pure-tone thresholds word were quiet threshold-shaped maskers that shifted...
A maximum-likelihood method was applied in measurements of frequency and intensity discrimination for aged young normal-hearing subjects with closely matched audiograms. This preferred over other psychophysical procedures because it is efficient controls experimental variance, features that are highly desirable testing subjects. In order to implement the method, psychometric functions each task were also measured from using a constant-stimuli procedure. For subjects, differential thresholds...