A5044047825- Human Health and Disease
- Healthcare Systems and Public Health
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Nanoparticles: synthesis and applications
- Technology and Human Factors in Education and Health
- Biomarkers in Disease Mechanisms
- Medical and Agricultural Research Studies
- Advanced Chemical Sensor Technologies
- Food Industry and Aquatic Biology
- Occupational Health and Safety Research
- Health, Environment, Cognitive Aging
- Air Quality Monitoring and Forecasting
- Food Safety and Hygiene
- Analytical Chemistry and Chromatography
- Aluminum toxicity and tolerance in plants and animals
- Chemical Reactions and Isotopes
- Carcinogens and Genotoxicity Assessment
- Anesthesia and Neurotoxicity Research
- Immunotoxicology and immune responses
- Curcumin's Biomedical Applications
- COVID-19 epidemiological studies
- Neurological Disorders and Treatments
- Economic and Technological Systems Analysis
- Stress Responses and Cortisol
Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
2016-2025
Russian Academy of Sciences
2014-2024
Department of Medical Sciences
2023-2024
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2017-2023
Perm State University
2015-2023
Quality Research
2023
Perm National Research Polytechnic University
2023
Perm State Medical Academy
2016-2022
Institute of Mathematics and Mathematical Modeling
2014-2021
The Russian Presidential Academy of National Economy and Public Administration
2021
We took several cities (Bratsk, Krasnoyarsk, Norilsk, and Chita) included as priority ones into the "Pure air" federal project an example showed that it was not sufficient to only aim at reducing gross emissions of pollutants apply a criterion assess efficiency air-protecting activities performed in city.Health risk calculations, comparative analysis assessment medical statistical data on population applying for aid, combined with results profound targeted examinations, revealed demographic...
A group of authors has developed a multilevel mathematical model that focuses on functional disorders in human body associated with various chemical, physical, social, and other factors. At this point, the researchers have come up structure, basic definitions concepts at “macrolevel” allow describing processes as whole. Currently we are working “mesolevel” organs systems. Due to complexity tasks, paper deals only one meso-fragment digestive system model. It describes some aspects related...
When industrial objects emitting substantial masses of dust and gas mixtures are located within a settlement or close to its borders, it often results in poorer quality the environment damages population health.Such situation is typical for many cities country; primarily, those that included into "Pure air" Federal project, part "Ecology" National project.Negative effects produced by set various substances emitted from industries.And quite great numbers people exposed such emissions as...
Introduction. Non-ferrous metallurgy holds a specific place among various productions that create potential health risks due to environmental pollution. Total emissions from the branch enterprises into ambient air reach three million tons (aluminum, fluorine, nickel, manganese, benzo(a)pyrene, sulfur dioxide and trioxide, hydrocarbon, etc.) per year, which accounts for 18% of total all stationary sources. Implementation etiopathogenetic prevention programs is promising trend in preventing...
Introduction. A pressing issue is the possible impact of exposure to heavy metals on occurrence and progression cardiovascular diseases (CVD) among pediatric population. Purpose. To evaluate immune genetic profile in CVD children under environment contamination with nickel copper. Materials methods. Ninety seven living industrial center Perm region were examined. Observation group (45 patients), comparison (52 cases) without CVD. Annexin V CD16+CD56+ receptors determined by cytofluorometry....
Evaluation of the role Ile105Val polymorphism GSTP1 gene (rs1695) in processes cell death regulation child population under conditions bioexposure to aluminum was carried out. The level contamination urine children observation group exceeded similar indicators comparison by 1.53 times (p=0.004). A change ratio immune populations observed (a decrease CD3+- and CD4+-lymphocytes, p=0.000-0.010) against background a violation overall oxidant-antioxidant balance (p=0.004-0.042). We identified...
Introduction. In this study, we estimated features of modifying effects produced by benzo(a)pyrene well as vaccine antigens the SARS-CoV-2 and Influenzavirus viruses on cytokine profile indicators under experimental conditions in vitro. Materials methods. To assess cytokine-producing function, there was studied a mixed population immunocytes, which cultured for 72 hours, followed analyzing enzyme immunoassay. Benzo(a)pyrene viral S protein hemagglutinins Influenzaviruses types A B were used...
The study of combined effects chemicals and their assessment is one among urgent issues hygiene preventive medicine. Chemicals with variable chemical composition that persist in environmental objects produce simultaneous on human health; given that, it a challenge for researchers to assess combinations composition. To identify key areas development improve the methodology addressing it, necessary systematize knowledge as regards studying patterns features toxicity. This review presents most...
Introduction. Diseases of the nervous system (NS) occupy a leading place in structure child prevalence. The environmental conditions create growing number stress-inducing factors able affecting body. Aluminum and its compounds are good example here, it, turn, is most common element on Earth. increase volume pollution objects with these chemical pollutants, aspects toxic properties relation to immune systems, attracting more attention. However, despite problem being obvious urgent be solved,...
The Pan-Eurasian Experiment (PEEX) is a new multidisciplinary, global change research initiative focusing on understanding biosphere-ocean-cryosphere-climate interactions and feedbacks in Arctic boreal regions the Northern Eurasian geographical domain. PEEX operates an integrative way it aims at solving major scientific society relevant questions many scales using tools from natural social sciences economics. agenda identifies most urgent large scale topics of...
The article presents an overview and summarizes the accumulated international national experience, highlighting formation main stages of development theoretical foundations practical significance use biomarkers in medico-ecological studies evaluations terms influence harmful chemical factors on human organism. It is shown that order to increase effectiveness evidentiary causal relationships developing negative effects modifying mechanism their with adverse environmental factors, need expand...
The changes in socio-economic conditions of the modern world require public authorities to improve methods management. index effectiveness this management is achievement objectives interest. Based on historical data, taking into account recommendations international organizations for assessment performance and efficiency Federal Service Surveillance Consumer Rights Protection Human Wellbeing it proposed use infectious morbidity rate indices population controlled by means vaccination; level...
It is shown in the article that since establishment 1992 and until now social health monitoring (SHM) operates as a complex open system of extended collection processing heterogeneous data about parameters environment, socio-economic indicators living population country's regions, medical demographic characteristics society whole individual groups.As part SHM Rospotrebnadzor annually performs hundreds thousands instrumental measurements objects environment Russian Federation.These federal...
Introduction. There is actual development of scientific and methodological support for the formation evidence base negative impact environmental factors on public health. Material methods. The hygienic assessment air quality territory with placement aluminum production without similar sources emissions was carried out, carcinogenic non-carcinogenic health risk estimated, chemical-analytical clinical-laboratory examination 235 children out to study effects influence studied critical organs...
The ongoing climate change makes its contribution to public health risks. These risks can be caused both due direct impacts of the process and modifying influence exerted by climatic factors on chemical levels in ambient air. Given that, it is advisable develop methodical approaches that give an opportunity quantify under combined air pollution them. In this study, we suggest eligible for calculating, assigning a category assessing acceptability exposures considering their pollution. We...
The paper dwells on issues related to quality of drinking water from centralized supply systems; spotting out priority health risk factors; and assessing efficiency control surveillance activities performed by Rospotrebnadzor in the sphere RF population.It was detected that most regions within social-hygienic monitoring mainly covered contents substances belonging 3 rd 4 th hazard categories while 1 st category were controlled only several regions.The highest shares samples exceeding...
Increasing the predictive potential of early diagnostics and correction negative outcomes is becoming especially relevant for preventing reducing personalized population health risks, including those caused by environmental exposures. The purpose study was to develop scientific methodological grounds iterative numerical prediction risk harm human under chemical design based on consistent implementation an algorithm system analysis development effects a exposure, from protein targets systemic...
Increasing the predictive potential of early diagnostics and correction negative outcomes is becoming especially relevant for preventing reducing personalized population health risks, including those caused by environmental exposures. The purpose study was to develop scientific methodological grounds iterative numerical prediction risk harm human under chemical design based on consistent implementation an algorithm system analysis development effects a exposure, from protein targets systemic...
Aim: scientific forecasting toxicity and evaluation potential hazard of the biological action aluminum oxide nanoparticles for human health. Methods: assessment hazards was carried out according to results forecasting-analytical modeling complexes indicators characterizing physico-chemical, molecular biological, biochemical, cytological ecological properties with calculation coefficients (D) incompleteness data (U) nanoscale aluminum. Own research on establishment size shape nanomaterial...
We performed comparative sanitary-hygienic assessment of regime, stress and intensity educational process in different establishments, a comprehensive secondary school an innovative establishment -lyceum.We detected that studying regime tended to be tight, classes were longer more intense than ordinary school, involved considerable intellectual, sensory emotional loads for children; such reached "1st category intense" level.Schoolchildren attending lyceums are also busy with additional...
Introduction. Search solutions to strategic tasks aimed at preservation of population health in the Russian Federation requires an increase productivity and efficiency public administration, including that performed by control surveillance organizations. Material methods. The article focuses on algorithm for assessing activities Federal Service Surveillance over Consumer Rights Protection Human Well-being organizations authorities. authors calculated morbidity mortality rate associated with...
On the basis of mathematical modeling links in system "environment – human health - control and supervisory actions Rospotrebnadzor", were obtained data on reliable dependences mortality morbidity rates population Russian regions frequency violations hygienic standards for content harmful chemical biological substances air, drinking water soils urban rural settlements. It is shown that Russia 2017 influence environment factors probabilistically associated with almost 64.9 thousand deaths...