A5007126780- Research on Leishmaniasis Studies
- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- Parasites and Host Interactions
- MicroRNA in disease regulation
- Advanced biosensing and bioanalysis techniques
- Insect Pest Control Strategies
- Insect Utilization and Effects
- Insect Resistance and Genetics
- Circular RNAs in diseases
- Reproductive System and Pregnancy
- Viral Infections and Vectors
- Transplantation: Methods and Outcomes
Ministério da Saúde
2025
Instituto Adolfo Lutz
2023-2025
Secretaria da Saúde
2023
Visceral leishmaniasis (VL) is a chronic systemic disease. In Brazil this infection caused by Leishmania (Leishmania) infantum. Extracellular vesicles (EVs) released species have different functions like the modulation of host immune systems and inflammatory responses, among others. This study evaluated participation EVs from L. (L.) infantum (Leish-EVs) in recognition humoral cellular response hosts with VL. Promastigotes were cultivated 199 medium and, log phase growth, they centrifuged,...
Visceral leishmaniasis (VL) is a zoonotic disease in which dogs are the main reservoirs. Until now, serological tests do not present satisfactory sensitivity for diagnosis of these hosts. One functions extracellular vesicles (EVs) related to immunological host response. Here, we evaluated ability EVs released by Leishmania (Leishmania) infantum promastigotes (Leish‐EVs) be source antigens use human visceral (HumVL) and canine (CanVL). A total 300 sera were tested. The 155 divided into 4...
Abstract This retrospective cohort study analysed extracellular vesicles (EVs) and microRNAs (miRNAs) excreted in canine sera from dogs with visceral leishmaniasis (CanVL). A total of 56 were divided into Group I (28, healthy dogs) II the same dogs, but already CanVL). CanVL was determined by clinical laboratory diagnoses. Canine ultra‐centrifuged to recover EVs (Can‐EVs). Analyses transmission electron microscopy, nanoparticle tracking analysis (NTA), sodium dodecyl sulfate‐poli‐acrylammide...
Visceral leishmaniasis (VL) is a chronic systemic disease. In Brazil this infection caused by Leishmania (Leishmania) infantum. Extracellular vesicles (EVs) released species have different functions like modulation of host immune system, inflammatory response, among others. This study evaluated the participation EVs from L. (L.) infantum (Leish-EVs) in stimulation humoral and cellular responses hosts with VL. Promastigotes were cultivated 199 medium and, log phase growth, they centrifuged,...
Toxoplasmosis causes serious harm to the fetus, as tachyzoite dissemination, during pregnancy in women developing primo-infection. microRNAs (miRNAs) are small non-coding RNAs, which have regulatory roles cells by silencing messenger RNA. Circulating miRNA promising biomarkers for diagnosis and prognosticating numerous diseases. miRNAs levels estimated quantitative real-time PCR (qPCR). Relative quantification of expression requires proper normalization methods using endogenous controls....
O aparelho digestivo dos insetos é formado basicamente por um longo tubo que percorre seu corpo no sentido longitudinal, desde a boca até o ânus, denominado canal ou alimentar. espaço entre alimentar e paredes do chamado hemocele cavidade geral, grandemente ocupado sangue (hemolinfa). Neste sentido, estudos apontam hemolinfa de alguns insetos, conta da presença substâncias com potencial farmacológico, apresenta antibacteriano, antiviral, antifúngico, outros. trabalho, avaliamos efeito...