A5011349033- Bacteriophages and microbial interactions
- Vibrio bacteria research studies
- Plant Virus Research Studies
- Bacillus and Francisella bacterial research
- Hemoglobinopathies and Related Disorders
- Reproductive System and Pregnancy
- Infections and bacterial resistance
- Iron Metabolism and Disorders
- Identification and Quantification in Food
- Neuropeptides and Animal Physiology
- Laser Applications in Dentistry and Medicine
- Evolution and Genetic Dynamics
- Oral microbiology and periodontitis research
- Salivary Gland Disorders and Functions
- Pregnancy-related medical research
- Infant Health and Development
- Reproductive tract infections research
- Immunotoxicology and immune responses
- Microbial infections and disease research
- Pain Mechanisms and Treatments
- Hepatitis C virus research
- Multiple Sclerosis Research Studies
- Trace Elements in Health
- Infant Nutrition and Health
- Antibiotic Resistance in Bacteria
Mazandaran University of Medical Sciences
2022-2024
Tehran University of Medical Sciences
2015-2022
Hamedan University of Medical Sciences
2017-2021
University of Mazandaran
2021
Antibiotic resistance causes around 700,000 deaths a year worldwide. Without immediate action, we are fast approaching post-antibiotic era in which common infections can result death. Pseudomonas aeruginosa is the leading cause of nosocomial infection and also one three bacterial pathogens WHO list priority bacteria for developing new antibiotics against. A viable alternative to use phages, viruses. Yet, isolation phages that efficiently kill their target has proven difficult. Using...
Abstract Background P. aeruginosa is the primary source of hospital-acquired infections. Unfortunately, antibiotic resistance growing to precariously high levels, making infections by this pathogen life-threatening and hard cure. One possible alternative antibiotics use phages. However, isolation phages suitable for phage therapy— be lytic, efficient, have a broad host range —against some target bacteria has proven difficult. To identify best places look these against we screened hospital...
Morphine, a potent opioid analgesic, plays critical role in pain management but elicits complex effects on the central nervous system (CNS), demonstrating both beneficial and detrimental outcomes. This paper reviews preclinical studies to examine morphine's interactions with CNS, notably via binding receptors, leading analgesia as well series of adverse effects, including addiction, tolerance, neurological impairments. Acute exposure morphine alters neurotransmitter activity, gene...
SUMMARY Background Hepatitis B is a significant health problem and more than 350 million individuals are infected with hepatitis virus ( HBV ) globally. About 5% of these coinfected D HDV ). HBV–HDV coinfection increases the rate fulminant hepatitis, chronic cirrhosis. This study aimed to evaluate epidemiology in positive for surface antigen HBsAg who were referred Tehran Blood Transfusion Clinic from 2011 2012. Materials Methods ‐positive attending this clinic tested anti‐HDAg antibodies...
Wound infections are the primary cause of sepsis in burn wound patients and increase burn-related morbidity mortality.Gram-negative Gram-positive bacteria induce wounds.Conventional antimicrobial therapy is recognized as most successful therapeutic intervention to combat wounds.Unfortunately, resistance could be catastrophic lead treatment failure.Burn need topical treatment.Phages an alternative for antibiotics can used a monotherapy with antibiotic-resistant pathogens or applied...
Assessment of the Stability Pseudomonas aeruginosa-specific Myoviridae Bacteriophages in Mupirocin and Abukhalsa Burnt Ointments
Antimicrobial resistance (AMR) is a global health threat because of the emergence infections with multidrug-resistant (MDR) bacterial strains. Combination therapy, involving both phages and antibiotics, being explored to approach this burden. This combination therapy offers promising solution by overcoming resistance, enhancing treatment efficacy, serving as an alternative combat infections. However, challenges like phage need for extensive clinical trials must be addressed. Nevertheless,...
Background: Chlamydia pneumonia has currently been proposed to be involved in multiple sclerosis (MS) pathogenesis. The aim of this study was evaluate the serum level anti-C. pneumoniae immunoglobulin G (IgG) patients with MS compared control group, which may helpful further understanding etiology. Methods: obtained from 66 people and 20 healthy as patient groups, respectively. Serums were matched patient's age, gender, place residence. Finally, IgG measured by a sandwich enzyme-linked...
Beta-thalassemia major patients typically require chronic transfusion and iron-chelating agents to reduce serum iron overload. Osveral® is an available Iranian brand name of deferasirox used by majority thalassemic patients. The aim this study was compare the efficacy vs. Exjade® in beta- thalassemia patients.In randomized clinical trial, all received a single daily dose 30 mg/kg either or for 6 months. Primary outcome mean bimonthly changes ferritin concentration secondary outcomes included...
Background: One of the most common food allergies in infants is cow’s milk allergy (CMA). There no available effective therapeutic strategy for this issue. It's important to develop approaches reduce risk allergy. The purpose study was investigate effect probiotics with protein intolerance. Materials and methods: This a randomized clinical trial full-term CMA diagnosis. These patients were divided into case control groups (receiving placebo probiotic). Clinical symptoms such as diarrhea,...