A5103071941- Central Venous Catheters and Hemodialysis
- Vascular Procedures and Complications
- Vascular anomalies and interventions
- Vascular Malformations Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
- Dialysis and Renal Disease Management
- Pelvic and Acetabular Injuries
- Venous Thromboembolism Diagnosis and Management
- Vascular Anomalies and Treatments
- Abdominal Trauma and Injuries
- Renal and Vascular Pathologies
- Liver Disease Diagnosis and Treatment
- Abdominal vascular conditions and treatments
- Peripheral Artery Disease Management
- Infectious Aortic and Vascular Conditions
- Esophageal and GI Pathology
- Clinical Reasoning and Diagnostic Skills
- Environmental Education and Sustainability
- Congenital gastrointestinal and neural anomalies
- Cardiac Arrhythmias and Treatments
- Innovations in Medical Education
- Analytical Chemistry and Chromatography
- Climate Change Communication and Perception
- Intestinal Malrotation and Obstruction Disorders
- Organ Transplantation Techniques and Outcomes
University of Birmingham
1967-2025
Queen Elizabeth Hospital Birmingham
2015-2025
NIHR Surgical Reconstruction and Microbiology Research Centre
2012-2024
National Health Service
2010-2024
Cwm Taf University Health Board
2023
University Hospitals Birmingham NHS Foundation Trust
2012-2021
Queen Elizabeth Hospital
2017-2020
Missouri State University
1995-2019
Edinburgh Royal Infirmary
2017
Transnational Press London
2015
Gadolinium based contrast agents (GBCA) have been linked to the occurrence of nephrogenic systemic fibrosis (NSF) in renal impaired patients. The exact interaction between various different available formulations and NSF is not completely understood, but has postulated. This association triggered public health advisory bodies issue guidelines best practice recommendations on its use. As a result, reported incidence NSF, as well published use GBCA-enhanced magnetic resonance imaging...
Dietary administration of probucol (0.5%, wt/wt) efficiently reduced total plasma cholesterol levels in apolipoprotein E-deficient mice (apoE-/-) by 40%, with decreases high density lipoprotein (HDL) and apoAI 70 50%, respectively. Paradoxically, however, aortic atherosclerotic plaques the probucol-treated apoE-/- formed more rapidly than untreated mice, lesions were two to four times larger mature regardless sex, age, genetic background (P < 10(-)6). Histologically, contained increased...
The effect of hepatic lipase (HL) deficiency on the susceptibility to atherosclerosis was tested using mice with combined deficiencies in HL and apoE. Mice lacking both apoE (hhee) have a plasma total cholesterol 917 +/- 252 mg/dl (n = 24), which is 184% that only (HHee; 497 161 mg/dl, n 20, p < 0. 001). increase mainly beta-migrating very low density lipoproteins, although high lipoprotein (HDLc) also increased (53 37 versus 20 13 0.01). Despite cholesterol, we found significantly decreased...
Conditional deletion of beta1 integrins in the intestinal epithelium, unlike epidermal and mammary epithelia, mice does not result decreased cell adhesion proliferation, but instead causes a profound increase epithelial proliferation with dysplasia polypoid structures. The increased inhibited differentiation that caused severe malnutrition early postnatal lethality. striking similarities between integrin-deleted neonatal defective Hedgehog signaling led to discovery expression was markedly...
This study addresses the question of whether developmental assessment centers are effective interventions. Career outcomes center participants ( n = 151) were evaluated with respect to ratings, activity, and acceptance feedback. Although comparison between a subgroup assessees 113) naturally occurring control group non‐assessees 167) showed no differences in terms career advancement, findings within assessee sample did show that activity related advancement. Findings also assessors' ratings...
Devices to permit percutaneous endovascular arteriovenous fistula formation have recently been introduced into clinical practice with promising initial evidence. As guidelines support a distal first policy, the question of whether an should be performed as option is introduced. The aims this study were compare matched cohort surgical radiocephalic fistulas.Using data from prospectively collected database over 3-year period, comparative analysis was performed.WavelinQ fistulas (group W, n =...
Pulmonary embolism (PE) is a potentially life-threatening complication of critical illness. In trauma and neurosurgical patients with contraindications to anticoagulation, inferior vena cava (IVC) filters have been used prevent PE, but their associated long-term rates difficulties filter removal limited use. The Angel catheter temporary device, which combined an IVC triple-lumen central venous (IVC filter-catheter) intended for bedside placement when no longer indicated.This study presents...
Purpose A palpable “thrill” is traditionally associated with success following arteriovenous fistula (AVF) surgery. thrill typically characterizes turbulent flow and this a paradox as turbulence driver of neointimal hyperplasia. Spiral laminar (SLF) has been described normal protective pattern in native arteries superior patency bypass grafts that generate it. The aim study was to define the within AVFs immediately post-operatively at follow-up assess maturation. Methods Doppler ultrasound...
The aim of this manuscript was to establish a consensus for the management acute and chronic venous obstruction among specialists in UK. Specialist physicians representing vascular surgery, interventional radiology hematology were invited 3 meetings discuss iliofemoral obstruction. outlined controversial areas, included topic-by-topic review; on completion reached when greater than 80% agreement each topic. Physicians from 19 UK hospitals agreed treatment protocols highlighted areas that...