A5000559088- Vaccine Coverage and Hesitancy
- Advanced Breast Cancer Therapies
- Economic and Financial Impacts of Cancer
- Breast Cancer Treatment Studies
- Influenza Virus Research Studies
- Multiple and Secondary Primary Cancers
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Respiratory viral infections research
- Hepatitis B Virus Studies
- Lung Cancer Treatments and Mutations
- Hepatitis Viruses Studies and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- HER2/EGFR in Cancer Research
- Hair Growth and Disorders
- Cancer Treatment and Pharmacology
- Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Child and Adolescent Health
- Chronic Lymphocytic Leukemia Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal cell carcinoma treatment
Pfizer (United States)
2020-2025
Pfizer (United Kingdom)
2023
Impact Technology Development (United States)
2020-2022
RTI Health Solutions
2014-2020
Triangle
2018-2020
RTI International
2019
Kaiser Permanente Center for Health Research
2013-2017
Janssen (United States)
2017
Johnson & Johnson (United States)
2017
Research Triangle Park Foundation
2015
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection (LRTI)-related hospitalizations in older adults. Without RSV-specific treatment for adults, testing uncommon, to potential underestimation RSV incidence real-world data studies. This study aimed quantify the frequency during LRTI-related adults inform interpretation estimates.Administrative and billing aged ≥ 65 years with primary or secondary diagnosis LRTI 2016-2019 seasons (October-April) were...
Background. Although vaccination with trivalent inactivated influenza vaccine (TIV) is recommended for all pregnant women, no effectiveness (VE) studies of TIV in women have assessed laboratory-confirmed outcomes. Methods. We conducted a case-control study over 2 seasons (2010–2011 and 2011–2012) among Kaiser Permanente health plan members metropolitan areas California Oregon. compared the proportion vaccinated 100 cases (confirmed by reverse transcription polymerase chain reaction)...
Identification of risk factors for severe respiratory syncytial virus (RSV) disease in adults could facilitate their appropriate vaccine recommendations. We conducted a systematic literature review (last 10 years PubMed/Embase) to identify quantitative estimates RSV infection outcomes high-income countries. Severe from included hospitalization, excess mortality, lower tract infection, or composite measure: RSV, which these and others, such as mechanical ventilation extended hospital stay....
The Advisory Committee on Immunization Practices recommends routine childhood vaccination by age 2 years, yet evidence suggests that only 2% to 26% of children receive vaccine doses at age-appropriate times (compliance). objective this study was estimate completion and compliance rates between birth years using recent, nationally representative data. Using a sample aged 24 35 months from the 2012 National Survey (NIS), present examined recommended vaccines. A state-specific examination also...
Despite longstanding recommendations for routine vaccination against influenza; pneumococcal; tetanus, diphtheria, acellular pertussis (Tdap); and herpes zoster (HZ) among the United States general adult population, vaccine uptake remains low. Understanding factors that influence coverage variability beyond national level are important steps toward developing targeted strategies increasing coverage. A retrospective analysis was conducted using data from Behavioral Risk Factor Surveillance...
Vaccination at age-appropriate intervals increases protection against morbidity and mortality; however, compliance rates among children remain low partly due to a complicated vaccination schedule. Use of combination vaccines reduces the number injections per visit; there is limited evidence quantifying effect on rates. To examine how impact childhood completion (receipt recommended doses) vaccinations) rates, this study analyzed data from 2012 National Immunization Survey (NIS), nationally...
ABSTRACT Background Hair loss due to alopecia areata (AA) can negatively impact patients’ health‐related quality of life (HRQoL). Patient‐reported outcome measures (PROMs) like the EQ‐5D‐5L and Alopecia Areata Patient Priority Outcomes (AAPPO) represent treatment outcomes guide decision‐making. However, potentially underestimates AA‐specific impacts, while AAPPO may provide a more disease‐specific assessment. Objectives This study uses emotional symptom (ES) activity limitations (AL)...
Vitiligo may negatively impact quality of life (QOL). This study aimed to classify patients on the basis vitiligo emotional/psychological and social functioning describe patient characteristics patient-reported outcome (PRO) responses for each profile. Physician surveys from Disease Specific Programme in France, Germany, Italy, Spain, USA were analyzed. PROs assessed using Patient Priority Outcomes (ViPPO), Work Productivity Activity Index-Vitiligo, Vitiligo-Specific Quality-of-Life...
Individuals with chronic respiratory conditions may be at increased risk for pertussis. We conducted a retrospective administrative claims analysis to examine the incidence and economic burden of diagnosed pertussis among adolescents adults in USA obstructive pulmonary disease (COPD) or asthma. Patients aged ⩾11 years pre-existing COPD (n = 343) asthma 1041) were matched 1:1 patients but without Differences all-cause costs ('excess' costs) during 45-day 3-month 6-month periods before after...
Adult vaccination coverage rates in the US are well below national targets, leaving many adults at increased risk. Additionally, typical calculations do not adequately approximate population immunity as they consider whether multidose vaccines were administered within recommended schedules. As timely administration of each dose optimizes overall vaccine effectiveness, we sought to document adherence and completion hepatitis A (HepA), B (HepB), combined (HepA-HepB) schedule an insured adult...
The American Academy of Pediatrics recommends exclusive breastfeeding to age 6 months. Although rates in the United States have been increasing over time, further improvements are needed meet Healthy People 2020 targets. Research aim: This study examined predictors initiation and maintenance among a population insured pregnant women.Participants were 1,149 women enrolled Pregnancy Influenza Project two Kaiser Permanente regions 2010-2011. Data collected through interviews at enrollment 1...
Early provisions of the Affordable Care Act (ACA) reduced financial barriers to preventive care, including routinely recommended vaccines; however, vaccination coverage remains suboptimal. This study examined characteristics routine adult vaccinations and potential missed opportunities for through lens healthcare resource utilization among adults in ACA era.This was a retrospective analysis claims from Truven Health MarketScan Commercial Claims Encounters (CCAE), Medicare Supplemental (MS),...
The impact of coronavirus disease 2019 (COVID-19) on the wellbeing breast cancer (BC) patients is not well understood. This study described psychosocial problems among these in United States (US) during COVID-19 pandemic. Data were collected from BC via an online self-report survey between 30 March–6 July 2021 to assess prevalence diagnosis history and potential depression, health-related quality life, COVID-related stress, financial toxicity. Patients with early-stage (eBC) metastatic (mBC)...
A challenge facing immunization registries is developing measures of childhood coverage that contain more information for setting policy than present vaccine series up-to-date (UTD) rates. This study combined milestone analysis with provider encounter data to determine when children either do not receive indicated immunizations during medical encounters or fail visit providers. Milestone status at key times between birth and age 2, recommended first become late. The a large population in the...
PurposeDespite recommended routine vaccination with meningococcal conjugate vaccine (MenACWY) at ages 11–12 years a booster age 16 years, national estimates indicate MenACWY uptake is lower in older adolescents than younger adolescents. This study aimed to identify factors associated among adolescents.MethodsCommercial Claims and Encounters (CCAE) Medicaid MarketScan Databases from 2011 2016 were retrospectively analyzed (2017) determine receipt of ≥1 dose during early (10.5 through 13...
To assess adherence and persistence with palbociclib therapy in patients HR+/HER2- metastatic breast cancer (mBC) a US real-world setting.This retrospective study evaluated dosing, adherence, using commercial Medicare Advantage Part D claims data from the Optum Research Database. Adult mBC who had continuous enrollment 12 months prior to diagnosis initiated first-line aromatase inhibitor (AI) or fulvestrant between 02/03/2015 12/31/2019 were included. Demographic clinical characteristics,...