A5037161801- Drug-Induced Hepatotoxicity and Protection
- Pesticide Exposure and Toxicity
- Phytochemistry and Biological Activities
- Pharmacological Effects of Natural Compounds
- Liver Disease Diagnosis and Treatment
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Free Radicals and Antioxidants
- Phytochemistry and Bioactive Compounds
- Animal Ecology and Behavior Studies
- Pesticide and Herbicide Environmental Studies
- Medicinal plant effects and applications
- Climate Change and Health Impacts
- Essential Oils and Antimicrobial Activity
- Toxic Organic Pollutants Impact
- Medicinal Plants and Bioactive Compounds
- Antifungal resistance and susceptibility
- Plant Toxicity and Pharmacological Properties
- Crystallography and molecular interactions
- Vitamin C and Antioxidants Research
- Aquaculture Nutrition and Growth
- Reproductive biology and impacts on aquatic species
- Environmental Toxicology and Ecotoxicology
- Heavy Metal Exposure and Toxicity
- Weed Control and Herbicide Applications
University of Sfax
2016-2025
The current study aimed to assess the antioxidant and antiproliferative effects of teucrium polium extract: computational in vivo rats. Three groups animals: Group (i) constitute control group; (ii) HeLa group received an intrafemoral inoculation cells (iii) constitue combination between + T. polium. plant was administered by gavage. Our results revealed that cell injection showed elevation aspartate aminotransferase (AST), alanine (ALT), alkaline phosphatase (ALP), total bilirubin (TB),...
This study is aimed to elucidate the possible antioxidant and protective effects of Artemisia campestris essential oil (ACEO) against deleterious chlorpyrifos (CPF) in rats. The vivo revealed increases aspartate aminotransferase (AST), alanine (ALT), lactate dehydrogenase (LDH), alkaline phosphatase (ALP) activities serum contents creatinine, urea, uric acid, cholesterol, triglycerides, low density lipoproteins (LDL), glucose rats treated with CPF as compared controls. Meanwhile, hepatic...
This study investigated the druggability, pharmacokinetics and ethyl acetate extract of Teucrium polium (EA T. polium) protective effect against carbon tetrachloride (CCl4) induced liver cirrhosis in rats. The total antioxidant capacity (TAC) scavenging activity were examined. vivo was based on use an animal model CCl4-induced cirrhosis. Four groups rats have been used: Group I: control rats; II: received CCl4 olive oil (0.5 mL/kg); III: EA (25 mg/kg) pretreatment for seven days by gavage...
Kalach 360 SL (KL), glyphosate (G) surfactant-based herbicides, is a systemic herbicide effective against weeds. It was applied in agriculture Tunisia and throughout the world, which can represent risk to non-target organisms. The aim of this study investigate morphological biochemical aspects ovary injury after exposure KL. Female Wistar rats were divided into three groups: group 1 used as control; 2 orally received 0.07 ml KL, (126 mg G/kg) 3 0.175 KL (315 each day for 60 days. subchronic...
This study aimed to investigate the protective effects of Teucrium polium (TP) on carbon tetrachloride (CCl4) induced spleen, erythrocyte’s oxidative stress, and genotoxicity in rats. TP was found contain large amounts polyphenols (150 mg GAE/G dry plant) flavonoids (60 QE/g quercetin plant). The CCl4 (0.5 ml/kg) treated rats exhibited significant reductions serum vitamin A (VA), E (VE) total antioxidant status (TAS). Thiobarbituric acid reactive substances (TBARS) conjugated dienes (CD)...
This work investigated the protective effects of Teucrium polium (T. polium) and vitamin C (Vit C) against carbon tetrachloride (CCl4) induced hepatotoxicity nephrotoxicity in rats. T. reduced Fer antioxidant power (FRAP) (IC50 = 0.89 mg/ml) 2, 2-diphenyl-1-picrylhydrazyl (DPPH) 0.049 µg/ml) than Vit C, FRAP 0.71 DPPH 0.029 µg/ml). Male albino Wistar rats were divided into six groups: Group I was used as controls, II received CCl4 olive oil (0.5 ml/kg) by gavage, III gavage after 3 d...
The aim of this study was to investigate the protective effects Teucrium polium (T. polium) on carbon tetrachloride (CCl4)-induced male reproductive system damage. T. and vitamin C (Vit C) sperm parameters, gonadotrophin testosterone levels, oxidative status testis tissue structure were assessed in CCl4-treated rats. CCl4 caused significant alteration parameters epididymal testicular tissues, a decrease hormone antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT)...
Yarrowia lipolytica is ubiquitous in the environment, opportunistic, and might be considered as one of causative agents catheter-related candidemia. Our work aimed to study some virulence factors Y. such hydrolases production biofilm formation with comparison most frequent Candida specie human disease. In sum, 58 clinical isolates lipolytica, 16 C. glabrata, 12 albicans were collected from Intensive care unit (ICU). All tested for enzymatic formation. glabrata able degrade casein, 98.2%...
The present study investigated the in vitro and vivo antioxidant capacities of Allium sativum (garlic) extract against deltamethrin-induced oxidative damage rat's brain kidney. result showed that highest extraction yield was achieved with methanol (20.08%). Among tested extracts, exhibited total phenolic, flavonoids contents activity. results deltamethrin treatment caused an increase acetylcholinesterase level (AChE) plasma, kidney conjugated dienes lipid peroxidation (LPO) levels as...
Urtica dioica (Urticaceae) has outstanding medicinal and pharmacological properties. This investigation was aimed to assess the chemical composition, total polyphenol flavonoid content, antioxidant, anti-proliferative, anti-inflammatory effects of essential oil (UDEO) GC/MS analysis performed standard antioxidative test, DPPH assay, reducing power as well anti-proliferative capacities UDEO against HeLa cell lines using MTT test. In addition, activities were evaluated paw thickness...
The aim of this study was to evaluate the anti-inflammatory activity Teucrium polium (TP). Rats were divided into four groups: group 1 controls received standard diet; 2 inflamed by carrageenan (Carr) (1% Carr); 3 as reference with Carr and treated Indometacine (Ind) (150 mg/kg bw) 4 pre0treated TP (5 g/L). Oedema volume measured h 5 after injection. Administration or Ind decreased levels hematology parameters relative reduced rats induced Carr. CRP, fibrinogen compared treated, a decrease...
Enzymatic thornback ray (Raja clavata) muscle hydrolysates have been shown to antioxidant and antihypertensive activities in vitro. The Neutrase hydrolysate exhibited the highest activities, so it was investigated along with undigested test their hypolipidemic, antioxidative fertility effects rats fed a high-cholesterol diet (HCD). Animals were allocated into four groups of 5 each: normal group (control), HCD group, two daily dose (Und) or (MH) at 0.7 g kg-1 body weight. All animals received...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)