Abdelfattah El Feki

ORCID: 0000-0002-4661-912X
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Drug-Induced Hepatotoxicity and Protection
  • Natural Antidiabetic Agents Studies
  • Pesticide Exposure and Toxicity
  • Heavy Metal Exposure and Toxicity
  • Bone Tissue Engineering Materials
  • Essential Oils and Antimicrobial Activity
  • Vitamin C and Antioxidants Research
  • Diet, Metabolism, and Disease
  • Phytochemistry and Biological Activities
  • Antioxidant Activity and Oxidative Stress
  • Cholesterol and Lipid Metabolism
  • Environmental Toxicology and Ecotoxicology
  • Diet and metabolism studies
  • Microbial Metabolites in Food Biotechnology
  • Curcumin's Biomedical Applications
  • Phytochemistry and Bioactivity Studies
  • Dental Implant Techniques and Outcomes
  • Pharmacological Effects of Medicinal Plants
  • Botanical Research and Applications
  • Selenium in Biological Systems
  • Fatty Acid Research and Health
  • Medicinal plant effects and applications
  • Phytochemistry and Bioactive Compounds
  • Protein Hydrolysis and Bioactive Peptides

University of Sfax
2016-2025

Hopital Universitaire Habib Bourguiba
2024

Hopital Universitaire Hedi Chaker
2021-2024

University of Gafsa
2021-2022

ORCID
2020

Badji Moktar-Annaba University
2011

University of Tsukuba
2008

Institut National des Sciences et Technologies de la Mer
2008

École Normale Supérieure
1984

This study was designed to test the antidiabetic and antioxidative activities of olive leaf oleuropein hydroxytyrosol. Diabetes in Wistar rats induced by intraperitoneal injections alloxan. The serum glucose cholesterol, hepatic glycogen, thiobarbituric acid-reactive substances (TBARS), components antioxidant system were examined. Diabetic showed hyperglycemia, hypercholesterolemia, increased lipid peroxidation, depletion enzymes activities. administration, for 4 weeks, hydroxytyrosol rich...

10.1021/jf901280r article EN Journal of Agricultural and Food Chemistry 2009-09-02

Abstract Background Rose-scented geranium ( Pelargonium graveolens L’Hér.), which is used in traditional Tunisian folk medicine for the treatment of hyperglycaemia, widely known as one medicinal herbs with highest antioxidant activity. The present paper conducted to test hypoglycemic and antioxidative activities leaf essential oil P. . Methods was administered daily orally rats at two doses 75 mg/kg 150 body weight (b.w.) 30 days. chemical composition oil, weight, serum glucose, hepatic...

10.1186/1476-511x-11-81 article EN cc-by Lipids in Health and Disease 2012-06-26

This study was designed to test the lipid-lowering and antioxidative activities of triacetylated hydroxytyrosol compared with its native compound, hydroxytyrosol, purified from olive tree leaves. Wistar rats fed a standard laboratory diet or cholesterol-rich for 16 weeks were used. The serum lipid levels, thiobarbituric acid-reactive substances (TBARS) level, as an indicator peroxidation, activity superoxide dismutase (SOD) well that catalase (CAT) examined. induced hypercholesterolemia...

10.1021/jf072589s article EN Journal of Agricultural and Food Chemistry 2008-04-01

diabetes is a serious health problem and source of risk for numerous severe complications such as obesity hypertension. Treatment its related diseases can be achieved by inhibiting key digestives enzymes-related to starch digestion secreted pancreas. The formulation omega-3 with fenugreek terpenenes was administrated surviving diabetic rats. inhibitory effects this oil on rat pancreas α-amylase maltase plasma angiotensin-converting enzyme (ACE) were determined. the findings revealed that...

10.1186/1476-511x-10-226 article EN cc-by Lipids in Health and Disease 2011-01-01

To examine chemical composition and antioxidant activity as well the in vitro α-amylase pancreatic lipase inhibitory activities of essential oil various extracts Juniperus phoenicea (J. phoenicea). Essential obtained by steam distillation were analyzed gas chromatography-mass spectrometry technique. The J. determined DPPH β-carotene bleaching methods. Gas analysis resulted identification 37 compounds, representing 96.98% oil; α-Pinene (24.02%), limonene (7.94%), D-3-Carene (16.9%),...

10.12980/apjtb.4.201414b114 article EN Asian Pacific Journal of Tropical Biomedicine 2014-07-01

The aim of this study was to evaluate the protective effects vitamin E and/or curcumin against diazinon (DZN) (an organophosphorus insecticide)-induced toxicity blood, liver and erythrocyte markers male Wistar rats. exposure rats DZN for 21 days provoked significant changes in red blood cell counts hemoglobin. Results showed that lipid peroxidation increased significantly DZN-treated rats, as evidenced by high thiobarbituric acid reactive substance levels. Alteration antioxidant system...

10.1177/0748233712446726 article EN Toxicology and Industrial Health 2012-05-18

Despite some studies related to Juniperus phoenicea L. (Cupressaceae), phytochemical and biological investigations of this plant remain unexplored.This work is the first report dealing with identification characterization volatile components flavonoids in hexane methanol extracts from J. leaves Materials methods: Antioxidant activity hexane, were determined by DPPH-radical scavenging assay. α-Amylase inhibitory was evaluated enzyme inhibition using vitro assay (each extract dissolved DMSO...

10.1080/13880209.2016.1230139 article EN cc-by Pharmaceutical Biology 2016-09-22

To find bioactive medicinal herbs exerting anti-asthmatic activity, we investigated the effect of an aqueous extract Urtica dioica L. (Urticaceae) leaves (UD), closest to Algerian traditional use.In this study, in vivo and antioxidant activities nettle extract.Adult male Wistar rats were divided into four groups: Group I: negative control; group II: Ovalbumin sensitized/challenged (positive control); III: received UD (1.5 g/kg/day) orally along experimental protocol; IV: protocol with...

10.1080/13880209.2017.1310905 article EN cc-by Pharmaceutical Biology 2017-01-01

The purpose of this study was to investigate the relationship between lipid effects, phenolic content, and antioxidative effects an ethyl acetate extract fenugreek. Wistar rats fed a standard laboratory diet or cholesterol-rich diets for 16 weeks were used. plasma levels, total phenolics, flavonoïd contents measured, thiobarbituric acid reactive substances (TBARS) antioxidant activities examined. Administration fenugreek significantly lowered levels cholesterol (TC), triglycerides (TG),...

10.1021/jf903186w article EN Journal of Agricultural and Food Chemistry 2010-01-28

The protective effect of the common mallow (Malva sylvestris) decoction on renal damages in rats induced by ammonium metavanadate poisoning was evaluated. On one hand, vanadium toxicity is associated to production reactive oxygen species, causing a lipid peroxidation and an alteration enzymatic antioxidant defence. other many medicinal plants are known possess radical scavenging properties, thanks presence flavonoids. These properties were confirmed Malva sylvestris two separate methods;...

10.1186/1476-511x-10-65 article EN cc-by Lipids in Health and Disease 2011-04-23

Methomyl (MET) is used worldwide in agriculture and health programs. Besides its advantages the agriculture, it causes several toxic effects. The objective of this study was to examine potential ability vitamin C and/or selenium (Se), alleviate oxidative damage parameters, against MET-induced changes blood biochemical markers liver kidney male Wistar rats. animals were randomized into five groups eight each: group I served as control rats; II received MET (8 mg/kg body weight (BW)) drinking...

10.1177/0748233712468020 article EN Toxicology and Industrial Health 2012-12-06
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