A5000687527- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Drug-Induced Hepatotoxicity and Protection
- Pesticide Exposure and Toxicity
- Air Quality and Health Impacts
- Nigella sativa pharmacological applications
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Natural Antidiabetic Agents Studies
- Vitamin C and Antioxidants Research
- Smoking Behavior and Cessation
- Carcinogens and Genotoxicity Assessment
- Retinoids in leukemia and cellular processes
- Thyroid Disorders and Treatments
- Selenium in Biological Systems
- Heavy Metal Exposure and Toxicity
- Medicinal plant effects and applications
- Bee Products Chemical Analysis
- Moringa oleifera research and applications
- Arsenic contamination and mitigation
- Liver Disease Diagnosis and Treatment
- Nuts composition and effects
- Saffron Plant Research Studies
- Therapeutic Uses of Natural Elements
- Environmental Toxicology and Ecotoxicology
Badji Moktar-Annaba University
2015-2024
Bakhtar University
2022
Ministère du travail, de l'emploi et de l'insertion
2004-2006
Hôpital Arnaud de Villeneuve
2006
Inserm
2006
The aim of this study was to evaluate the protective effects vitamin E and/or curcumin against diazinon (DZN) (an organophosphorus insecticide)-induced toxicity blood, liver and erythrocyte markers male Wistar rats. exposure rats DZN for 21 days provoked significant changes in red blood cell counts hemoglobin. Results showed that lipid peroxidation increased significantly DZN-treated rats, as evidenced by high thiobarbituric acid reactive substance levels. Alteration antioxidant system...
To find bioactive medicinal herbs exerting anti-asthmatic activity, we investigated the effect of an aqueous extract Urtica dioica L. (Urticaceae) leaves (UD), closest to Algerian traditional use.In this study, in vivo and antioxidant activities nettle extract.Adult male Wistar rats were divided into four groups: Group I: negative control; group II: Ovalbumin sensitized/challenged (positive control); III: received UD (1.5 g/kg/day) orally along experimental protocol; IV: protocol with...
Methomyl (MET) is used worldwide in agriculture and health programs. Besides its advantages the agriculture, it causes several toxic effects. The objective of this study was to examine potential ability vitamin C and/or selenium (Se), alleviate oxidative damage parameters, against MET-induced changes blood biochemical markers liver kidney male Wistar rats. animals were randomized into five groups eight each: group I served as control rats; II received MET (8 mg/kg body weight (BW)) drinking...
Wahiba Amraoui, Nesrine Adjabi, Fatiha Bououza, Mahieddine Boumendjel, Faiza Taibi, Amel Cherif Abdennour, and Mahfoud Messarah. ToxicolRes 2018;34:231-9. https://doi.org/10.5487/TR.2018.34.3.231
The aqueous and hydroalcoholic extracts of borage (Borago officinalis) leaves from Annaba region (Algeria) were preliminary analyzed for their phenolic profile (total phenolics, total flavonoids, flavonols, tannins anthocyanins). These evaluated antioxidant properties by different methods such as DPPH radical scavenging, test NBT activity. two have exhibited a high antiradical capacity. Indeed, the ethanolic extract showed lower IC50 values highest amount phenolics (94.09 ± 1.72 mg gallic...
To investigate the antioxidant and hepatoprotective properties of Juniperus phoenicea (J. phoenicea) berries against CCl4-induced oxidative damage in rats. Hepatotoxicity was induced albino Wistar rats by single dose CCl4 dissolved olive oil (1 mL/kg BW, 1/1 oil, i.p.). Aqueous extract J. (AEJP) administered at 250 mg/kg/day gavage for 12 days. Obtained results revealed that administration caused a significant increase plasma ASAT, ALAT, ALP LDH activities total bilirubin concentration,...
In the present study, we investigate phytochemical composition and nephroprotective effects as well antioxidant properties of Artemisia herba alba aqueous extract in alloxan-induced experimental diabetes rats.Wistar rats were divided into four groups seven each: Group I: Normal control (NC) received saline solution at 9‰ given by intraperitoneal way; II: Diabetic (DC) alloxan (150 mg/kg b.w) intraperitoneally; III: (NC + AHA) treated orally AHA (400 mg/kg/b.w); IV: (DC intraperitoneally...
This study aimed to identify the phytochemical compounds of Matricaria pubescens by LC-MS/MS and evaluate potential protective effect its supplementation in high-fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) adult rats through modulation oxidative stress histopathological changes. Twenty-four male were randomly divided into four groups. The first group served as control received standard diet. second (HFD) a only (30 % sheep fat). third group's (control+MP) animals...
Introduction and aim. Lung adenocarcinoma (LADC) is the most diagnosed histological subtype of lung cancer lead ing cause death in men Algeria. Defining circumstances that preceded diagnosis improves manage ment options reduces its incidence. However, data for this critical period are lacking. We report case a patient whose onset severe COVID-19 incidental finding an undefined LADC overlapped delayed care malignancy. Case description. present 65-year-old man, with invasive discovered during...
The present work was undertaken to evaluate the protective effect of an aqueous extract green tea (GT, Camellia sinensis) leaves against arsenic (NaAsO₂)-induced biochemical toxicity and lipid peroxidation production in experimental rats. treatment with exhibited a significant increase some serum hepatic renal parameters (alanine aminotransferase, aspartate alkaline phosphatase, total protein, albumin, bilirubin, cholesterol, urea creatinine). But co-administration GT has increased level...
The current study was conducted to explore the phytochemical composition and in vitro antioxidant activities of Moringa oleifera (MO) leaf aqueous extract, as well its vivo modulatory effects on abamectin (ABM) induced oxidative stress rat erythrocytes brain. Animals were randomly divided into four groups. first group served a control received distilled water by gavage. second (1 mg/kg b.w. drinking water). third M. extract (200 gavage). fourth (ABM‐MO) combination ABM MO. inhibited...
Context: Pistacia lentiscus L. (Anacardiaceae) is an evergreen shrub widely distributed throughout the Mediterranean region. oil (PLo) was particularly known in North African traditional medicine. Thus, people of these regions have used it externally to treat sore throats, burns and wounds, as well they employed internally for respiratory allergies. PLo rich essential fatty acids, vitamin E polyphenols. As a very active site metabolism, liver reported be susceptible arsenic (As)...
Chronic hyperglycemia and excess reactive oxygen species overproduced in diabetes were associated with oxidative stress, led to continuous injury functions damage different organs: eyes, kidneys, neural cardiovascular system. The present study was undertaken evaluate the protective effect of Artemisia herba alba (AHA) leaf powder against alloxane-induced diabetic rats. Rats randomly divided into four groups: Group I controls received saline solution 9%; II treated 150 mg alloxane/(kg body...
Background: Nitrate (NO3) is the most common chemical contaminant in world’s ground water aquifer. Oxidative stress has been proposed as a possible mechanism involved NO3 toxicity on non-target organism.
 Objectives: The current study aimed to elucidate potential protective effect of Telfairia occidentalis (pumpkin seed oil, PSO) against hepatotoxicity induced by sodium nitrate.
 Methods: Wistar rats were exposed either NaNO3 (200 mg/kg bw) drinking water, or 4ml PSO/kg bw gavage...
The objective of this study was to evaluate the potential protective effect Atriplex halimus aqueous leaves extract (AHAE) against acute carbon tetrachloride (CCl4)-induced oxidative stress in rats. Rats were randomly divided into four groups: group (C) served as a control treated with 1 ml/(kg bw) olive oil, and (CCl4) ml CCl4/(kg dissolved oil administered by intraperitoneal way. (CCl4+AHAE) have received CCl4 200 mg AHAE/(kg bw). Animals mg/(kg AHAE. A significant increase malondialdehyde...