- Animal Nutrition and Physiology
- Regulation of Appetite and Obesity
- Biochemical Analysis and Sensing Techniques
- Neuropeptides and Animal Physiology
- Genetic and phenotypic traits in livestock
- Livestock and Poultry Management
- Adipose Tissue and Metabolism
- Hypothalamic control of reproductive hormones
- Biochemical effects in animals
- Animal Genetics and Reproduction
- Receptor Mechanisms and Signaling
- Animal Behavior and Welfare Studies
- Chromosomal and Genetic Variations
- Meat and Animal Product Quality
- Pharmacological Effects and Assays
- Diet and metabolism studies
- Vitamin D Research Studies
- Acute Lymphoblastic Leukemia research
- Agriculture, Soil, Plant Science
- Genetic Mapping and Diversity in Plants and Animals
- DNA Repair Mechanisms
- Carcinogens and Genotoxicity Assessment
- Diet, Metabolism, and Disease
- Effects of Environmental Stressors on Livestock
- Biocrusts and Microbial Ecology
Nippon Veterinary and Life Science University
2013-2025
Hiroshima University
2007-2014
RIKEN BioResource Research Center
2010
National Cancer Center
1994-1995
Abstract The release of Nτ-methylhistidine from muscle cells into the culture medium is considered an index protein breakdown. aim this study was to establish a quantitative method for measuring intercellular concentrations and its isomer Nπ-methylhistidine in C2C12 myotubes via liquid chromatography–tandem mass spectrometry with stable-isotope dilution analysis. acceptable linear ranges detection were both 0.5 250 pmol/mL; r2 = 1.000 (Nτ-methylhistidine), 0.999 (Nπ-methylhistidine). Culture...
The relationship between taste sensitivity and the number of buds using a bitter tastant, quinine hydrochloride, was investigated in White Leghorn, Rhode Island Red, broiler chickens. Leghorn Red strains were able to perceive 2.0 mmol/L but chickens higher than that Broiler perceived 0.5 hydrochloride. strain lowest, then strain, with highest well correlated sensitivity. Therefore, we suggest is vital factor perception may be useful selecting appropriate feeds for
It is known that thermal conditioning at an early age results in improved heat tolerance, and reduces mortality when re-exposed to later life chickens. However, the mechanism of not fully understood. The objective this study was investigate effect on physiological behavioral responses acute heat-exposed chicks. Six-day-old chicks (White Plymouth Rock) were exposed high temperature 40°C for 3 h while control kept 30°C. Four days after treatment, both groups challenged 15 min. We found...
It is important to quantify and estimate stressful stimulation because stress appears limit productivity welfare in poultry. The purpose of this study investigate the effect acute isolation (5, 10 or 30min) on levels blood parameters (glucose, free fatty acid (FFA) corticosterone (CORT)) diencephalic related peptide gene expressions (corticotrophin-releasing hormone (CRH) arginine vasotocin (AVT)) neonatal chicks. Although treatment did not affect concentration plasma glucose (P>0.05), FFA...
The Tosa-no-Onagadori (briefly Onagadori) is one of the native Japanese chickens that characterized by extremely long tail feathers in males, and thus designated as a "Special National Natural Treasure" Japan. We investigated timing sexual maturity Onagadori White Leghorn hens quality first 10 eggs laid these young to obtain basic information for reproducing efficiently also assess their usefulness research material quantitative trait loci (QTL) analysis egg-related traits. reached at around...
The effects of intracerebroventricular injection L-tryptophan on feeding behavior and the levels brain neurotransmitters (amino acids or monoamines) were investigated in ad libitum chicks. tryptophan treatment (3 6μmol) significantly inhibited food intake chicks at 30min postinjection. serotonin (5-HT) its metabolite, 5-dihydroxyindolacetic acid, treated with higher than those saline 15min However, there no differences catecholamines (adrenaline, noradrenaline dopamine) amino acid (e.g.,...
The aim of the present study was to determine if some naturally-occurring substitutions amino acid residues insulin could act differentially within central nervous system (CNS) neonatal chicks control ingestive behavior. Intracerebroventricular (ICV) administration chicken (20ng) inhibited food intake in ad libitum over 120-min experiment period. A lower dose (2ng) also shows a suppressive effect at 60min post-injection, but not 30 and 120min. Similar insulin, higher porcine significantly 60...
To explore metabolic characteristics during the post-hatch developmental period, metabolomic analyses of breast muscle and plasma were performed in chickens. The most significant growth-related changes metabolite levels observed between seven 28 days age. Some these metabolites are essential nutrients or reported as growth-promoting metabolites. In muscle, two imidazole dipeptides-carnosine its methylated metabolite, anserine-increased with development. These dipeptide may be, part,...
Abstract We examined the effects of oral administration L‐citrulline (L‐Cit) on plasma metabolic hormones and biochemical profile in broilers. Food intake, water body temperature were also analyzed. After dual (20 mmol/head/administration) L‐Cit, broilers exposed to a high ambient (HT; 30 ± 1°C) chamber for 120 min. Oral L‐Cit reduced ( p < .001) rectal intake was increased .05) by heat stress, but it L‐Cit. Plasma levels 3,5,3′‐triiodothyronine, which initially .0001) due .01) insulin...
In this study, we aimed to develop a population pharmacokinetic model for CPT‐11 and use the Bayesian method estimate parameters in each of 43 patients who received combined therapy consisting etoposide. The group was divided into first second data sets 30 13 patients, respectively. We developed based on set. individual [area under concentration curve (AUC) clearance (CD] were subsequently estimated by using Plasma concentrations measured high‐performance liquid chromatography, compartmental...
Two experiments were conducted to evaluate the usefulness of urinary creatinine levels as a criterion for estimation protein and amino acid requirements in poultry. Here we studied effects dietary precursor creatinine, methionine arginine, on excretion experiments. Both used 15 Chunky broilers chicks that 8 days old. The assigned three groups, with five each, fed an experimental diet 7 days. diets mainly consisted corn soybean meal, contained deficient, adequate, or excessive arginine 1 2,...
β-Endorphin is an endogenous ligand for both mu- and delta-opioid receptors (MOR DOR), has important role in feeding behavior the central nervous system mammals. The present study was done to elucidate whether injection of β-endorphin enhances neonatal chicks investigate interaction with MOR DOR. We found that intracerebroventricular (ICV) (50pmol) significantly stimulated food intake during 60-min period postinjection. In addition, orexigenic effect attenuated by MOR, but not DOR...
This study was conducted to investigate the influence of in ovo vitamin D3 (Vit D3) administration on growth broiler chickens when Vit dissolved soybean oil. Sixty Ross eggs were incubated at 37.8°C and >60% relative humidity. Distilled water, oil, or (60 IU / 0.5 mL) administered Day 18 incubation. Seven days after hatching, chicks sexed, 12 birds (six female six male) close average body weight (BW) each treatment selected their BW continuously recorded until 28 age, then sacrificed. Liver...