A5007015777- Liver Disease and Transplantation
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Venous Thromboembolism Diagnosis and Management
- Hemodynamic Monitoring and Therapy
- Esophageal and GI Pathology
- Diagnosis and Treatment of Venous Diseases
- Gastric Cancer Management and Outcomes
- Palliative Care and End-of-Life Issues
- Immunodeficiency and Autoimmune Disorders
- Platelet Disorders and Treatments
- Respiratory Support and Mechanisms
- Pancreatitis Pathology and Treatment
- Mycobacterium research and diagnosis
- Heparin-Induced Thrombocytopenia and Thrombosis
- Potassium and Related Disorders
- Advanced X-ray and CT Imaging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Gastrointestinal Tumor Research and Treatment
- Global Health Workforce Issues
- Tracheal and airway disorders
- Eosinophilic Disorders and Syndromes
- Biosimilars and Bioanalytical Methods
- Ultrasound in Clinical Applications
University Hospitals Plymouth NHS Trust
2019-2024
King's College London
2023
Cork University Hospital
2023
University College Cork
2023
SGS Germany GmbH (Germany)
2023
Royal Cornwall Hospital Trust
2021-2022
Royal Cornwall Hospital
2022
Summary Background Anti‐drug antibodies are associated with treatment failure to anti‐TNF agents in patients inflammatory bowel disease (IBD). Aim To assess whether immunogenicity a patient's first agent would be the second, irrespective of drug sequence Methods We conducted UK‐wide, multicentre, retrospective cohort study report rates and second therapies 1058 IBD who underwent therapeutic monitoring for both infliximab adalimumab. The primary outcome was agent, defined at any timepoint as...
BACKGROUND Spontaneous bacterial peritonitis (SBP) is one of the most important complications patients with liver cirrhosis entailing high morbidity and mortality. Making an accurate early diagnosis this infection key in outcome these patients. The current definition SBP based on studies performed more than 40 years ago using a manual technique to count number polymorphs ascitic fluid (AF). There lack data comparing traditional cell method automated counter. Moreover, international...
Background The Joint Advisory Group on Gastrointestinal Endoscopy (JAG) conducts a biennial census of UK endoscopy services. 2023 aimed to assess the current status services and compare them with pre-pandemic benchmark data. Methods An electronic survey was sent all JAG participating in April 2023. Key domains included activity, waiting times, workforce safety. Whole service level paired comparison made 2019 Results There were 334 responses representing 443 JAG-participating (86.7% response...
<h3></h3> SBP is a major decompensation of cirrhosis. It related to development HRS, ACLF and high mortality. Therefore, it important make quick reliable diagnosis start specific treatment promptly. The definition SBP, manual cell count ≥250 PMN/mm3 on ascitic fluid (AF), was adopted in 2000 based small studies performed the 70–80's. current precision counters have not been compared with classic method. In this retrospective study, we method two different automated machines: Sysmex XE Abbott...
<h3>Introduction</h3> Training a future endoscopy workforce is vital to support increasing demand for services, but can be limited by current acute unit capacity. Involvement of the independent sector may offer an alternative option training. After collaborative discussion between NHS trusts, integrated care board, regional training academy and provider, pilot program was initiated. This study aims assess practical involvement with endoscopist <h3>Methods</h3> A JAG accredited provided 'cold...
<h3>Introduction</h3> Malnutrition is a significant problem for patients with motor neurone disease (MND). NICE recommend gastrostomy insertion nutritional support discussed at an early stage before respiratory impairment and weight loss increase the risks beyond acceptable limits. The ProGAS study found no mortality difference between percutaneous endoscopic (PEG) or radiologically inserted (RIG) tube placement, nor did it provide definitive guidance concerning timing route of insertion....
<h3>Introduction</h3> End of life care (EOLC) refers to given patients who are likely be within their last year life. Death related advanced chronic liver disease (ACLD) is often heralded by a prolonged decline. Clinical encounters therefore represent key opportunities for planning (ACP) and optimised EOLC in this cohort, supported specialist palliative services (SPCS). However, the limitations current provision increasingly recognised. We reviewed practice across South West England identify...