Abstract Background Posttraumatic stress disorder (PTSD) and stress/trauma exposure are cross-sectionally associated with advanced DNA methylation age relative to chronological age. However, longitudinal inquiry examination of associations between a broader range psychiatric disorders is lacking. The aim this study was examine if PTSD, depression, generalized anxiety, alcohol-use predicted acceleration over time (i.e. an increasing pace, or rate advancement, the epigenetic clock). Methods...

Rapid advances in human microbiome research point to an increasing range of health outcomes related the composition individual's microbiome. To date, much has focused on individual health, with a paucity attention public implications. This is critical oversight owing potentially shared nature across communities and vertical horizontal mechanisms for transferring microbiomes among humans. We explored some key ethical social implications health. (1) insights from about damage prevalent...

Access to family planning health services in Canada has been historically inadequate and inequitable. A potential solution appeared when Health approved mifepristone, the gold standard for medical abortion, July 2015. We sought investigate factors that influence successful initiation ongoing provision of abortion among Canadian professionals how these relate policies, systems, service access throughout Canada.We conducted 1-on-1 semistructured interviews with a national sample...

United States-based biorepositories are on the cusp of substantial change in regulatory oversight at same time that they increasingly including samples and data from large populations, e.g. all patients healthcare system. It is appropriate to engage stakeholders these populations new governance arrangements. We sought describe community recommendations for biorepository using deliberative engagement (DCE), a qualitative research method designed elicit lay perspectives complex technical...

Abstract Let G be a finite group and let H ≤ . We refer to | || C ( )| as the Chermak–Delgado measure of with respect Originally described by Chermak Delgado, collection all subgroups maximal measure, denoted 𝒞𝒟( ), is sublattice lattice In this paper we note that if ∈𝒞𝒟( ) then subnormal in prove K second × )=𝒞𝒟( )×𝒞𝒟( additionally describe ≀ p where has nontrivial centre an odd prime determine conditions for wreath product member its own lattice. also examine behaviour centrally large...

Abstract Background Repeat cesarean delivery is the single largest contributor to escalating rate worldwide. Approximately 80 percent of women with a past are candidates for vaginal birth after ( VBAC ), but in Canada less than one‐third plan . Emerging evidence suggests that these trends may be due part nonclinical factors, including care provider practice patterns and delays access surgical anesthesia services. This study sought explore maternity providers’ decision makers’ attitudes...

Abstract Background Since Canadian drug regulatory approval of mifepristone for medical abortion in 2015 and its market availability January 2017, the role pharmacists provision has changed rapidly. We sought to identify factors that influenced initiation from perspectives pharmacists, bridging two frameworks — Diffusion Innovation Health Service Organizations integrated knowledge translation. Methods conducted one-on-one semi-structured interviews with residing Canada who intended stock...

Abstract. For a finite group G with subgroup H , the Chermak–Delgado measure of in refers to <m:math xmlns:m="http://www.w3.org/1998/Math/MathML"> <m:mrow> <m:mo>|</m:mo> <m:mi>H</m:mi> <m:mspace /> </m:mrow> <m:msub> <m:mi>C</m:mi> <m:mi>G</m:mi> </m:msub> <m:mo>(</m:mo> <m:mo>)</m:mo> </m:math> ${\vert \vert \,\vert C_G(H) }$ . The set all subgroups maximal form sublattice, <m:mi>𝒞𝒟</m:mi> $\mathcal {CD}(G)$ within lattice This paper examines conditions under which is chain <m:mn>0</m:mn>...

If G is a finite group with subgroup H, then the Chermak–Delgado measure of H (in G) defined as |H||C (H)|. The lattice G, denoted 𝒞𝒟(G), set all subgroups maximal measure; this moduar sublattice within G. In paper we provide an example p-group P, for any prime p, where 𝒞𝒟(P) isomorphic to 2 copies ℳ2 (a quasiantichain width 2) that are adjoined maximum-to-minimum. We introduce terminology describe structure, called 2-string 2-diamonds, and also give two constructions generalizing example....

Objectives: Mifepristone for first-trimester medical termination of pregnancy (MTOP) became available in Quebec 2018, one year after the rest Canada. Using theory Diffusion Innovation (DOI) and transtheoretical model change (TTM), we investigated factors influencing implementation mifepristone MTOP Quebec.Material Methods: Semi-structured interviews were conducted with 37 physicians early 2018. Deductive thematic analysis guided by DOI explored facilitators barriers to physicians' adoption...

Health workers, in short supply many low-and-middle-income countries, are at increased risk of SARS-CoV-2 infection. This study aimed to assess how South Africa, prepared protect its health workers from infection.This was a cross-sectional design applying participatory action research four provinces Africa. A semi-structured questionnaire and qualitative observational HealthWISE walkthrough assessment carried out collect data on occupational safety (OSH) systems 45 hospitals across identify...

Abstract Background During evolution from novice to expert, knowledge structure develops into an abridged network organized around pathophysiological concepts. The objectives of this study were examine the change in medical students one year and investigate association between use a conceptual framework (diagnostic scheme) long-term structure. Methods Medical students' metabolic alkalosis was studied after instruction later using concept-sorting. Knowledge labeled 'expert-type' if shared ≥ 2...

SummaryNeed a project to satisfy your craving for abstract algebra? Or do you have student nosing around office looking project? The Chermak–Delgado lattice is sublattice of the subgroup finite group. details its definition don′t require advanced group theory, though working with this can send one on journey through deeper, more techniques. This makes perfect starting point an undergraduate after algebra class. article guides curious reader series exercises about provide preparation and fuel...

Medication non-adherence is a substantial problem among patients with inflammatory arthritis (IA). Our aim was to explore IA patients' perspectives on strategies support medication adherence.We collaborated leading patient group and conducted qualitative study individuals who were taking at least one for their IA. An experienced facilitator led participants through focus exercise where asked design, then discuss, and/or tools supporting use. We applied thematic analysis using an iterative,...

Ways to address the increasing global health workforce shortage include improving occupational and safety of workers, particularly those in high-risk, low-resource settings. The World Health Organization International Labour designed HealthWISE, a quality improvement tool help workers identify workplace hazards find apply low-cost solutions. However, its implementation had never been systematically evaluated. We, therefore, studied HealthWISE seven hospitals three countries: Mozambique,...

<h3>Objective</h3> The aim of the study was to explore factors that contributed adoption opportunistic salpingectomies (removal fallopian at time hysterectomy or in lieu tubal ligation) by gynecologic surgeons British Columbia (where a knowledge translation initiative took place) and Ontario (a comparator where no place). We aimed understand why undertaken OVCARE resulted such dramatic uptake salpingectomy. <h3>Methods</h3> undertook qualitative evaluation clinicians9 decisions about whether...

Aim: Vascular leakage following cardiopulmonary bypass contributes to morbidity. Angiopoietin-1 and -2 are biomarkers of endothelial dysfunction. Our aim was characterize Ang-1 association with clinical characteristics outcomes. Methods: Observational cohort study measuring Ang-1/-2 a panel cytokines in adults undergoing bypass. Results: Ang-2 levels increased immediately postop whereas decreased over time. No significant correlation found other inflammatory mediators. High between the...